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Related papers: Characterization in Geant4 of different PET config…

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Positron emission tomography (PET) scanners continue to increase sensitivity and axial coverage by adding an ever expanding array of block detectors. As they age, one or more block detectors may lose sensitivity due to a malfunction or…

Medical Physics · Physics 2019-10-17 William Whiteley , Jens Gregor

In recent years, SiPM photoelectric devices have drawn much attention in the domain of time-of-flight-based positron emission tomography (TOF-PET). Using them to construct PET detectors with excellent coincidence time resolution (CTR) is…

Instrumentation and Detectors · Physics 2018-06-08 Liwei Wang , Yonggang Wang , Qiang Cao , Yong Xiao , Chong Liu

The present paper proposes a novel computational method for parametric imaging of nuclear medicine data. The mathematical procedure is general enough to work for compartmental models of diverse complexity and is effective in the…

Tissues and Organs · Quantitative Biology 2017-05-15 Mara Scussolini , Sara Garbarino , Gianmario Sambuceti , Giacomo Caviglia , Michele Piana

Studies of the human brain during natural activities, such as locomotion, would benefit from the ability to image deep brain structures during these activities. While Positron Emission Tomography (PET) can image these structures, the bulk…

Robotics · Computer Science 2023-11-30 Junxiang Wang , Iulian I. Iordachita , Peter Kazanzides

Scintillating homogeneous detectors represent the state of the art in electromagnetic calorimetry. Moreover, the currently neglected crystalline nature of the most common inorganic scintillators can be exploited to achieve an outstanding…

Images from Positron Emission Tomography (PET) deliver functional data such as perfusion and metabolism. On the other hand, images from Magnetic Resonance Imaging (MRI) provide information describing anatomical structures. Fusing the…

Image and Video Processing · Electrical Eng. & Systems 2018-06-19 Hiliwi Leake Kidane , Stephanie Bricq , Alain Lalande

We characterize the performance of two pixelated neutron detectors: a PMT-based array that utilizes Anger logic for pixel identification and a SiPM-based array that employs individual pixel readout. The SiPM-based array offers improved…

Instrumentation and Detectors · Physics 2024-01-31 J. Balajthy , P. Marleau , M. Sweany

Recent tests of a single module of the Jagiellonian Positron Emission Tomography system (J-PET) consisting of 30 cm long plastic scintillator strips have proven its applicability for the detection of annihilation quanta (0.511 MeV) with a…

Geant4, the leading detector simulation toolkit used in high energy physics, employs a set of physics models to simulate interactions of particles with matter across a wide range of energies. These models, especially the hadronic ones, rely…

High Energy Physics - Experiment · Physics 2023-09-25 Krzysztof Genser , Soon Yung Jun , Alberto Ribon , Vladimir Uzhinsky , Julia Yarba

Purpose: To demonstrate a proton imaging system based on well-established fast scintillator technology to achieve high performance with low cost and complexity, with the potential of a straightforward translation into clinical use. Methods:…

In the context of particle therapy monitoring, we are developing a gamma-ray detector to determine the ion range in vivo from the measurement of particle time-of-flight. For this application, a beam monitor capable to tag in time the…

Positron Annihilation Lifetime Spectroscopy (PALS) is a non-destructive radiological technique widely used in material science studies. PALS typically relies on an analog coincidence measurement setup and allows the estimate of the positron…

Instrumentation and Detectors · Physics 2019-08-14 Ming Fang , Nathan Bartholomew , Angela Di Fulvio

Background and purpose: In-beam Positron Emission Tomography (PET) is one of the modalities that can be used for in-vivo non-invasive treatment monitoring in proton therapy. PET distributions obtained during various treatment sessions can…

Positron Emission Tomography (PET) using time-of-flight information, which can greatly improve the quality of the reconstructed image, has recently become an exciting topic. In this work, 3.2mm*3.2mm*25mm finger-like LYSO crystals were used…

Instrumentation and Detectors · Physics 2015-07-17 Liu Jun-Hui , Xu Jiong-Hui , Cheng Feng-Feng , Li Dao-Wu , Zhang Zhi-Ming , Wang Bao-Yi , Wei Long

This article presents a novel technique for precise measurement of time and charge based solely on FPGA (Field Programmable Gate Array) device and few satellite discrete electronic components used in Positron Emission Tomography (PET).…

Segmentation is an important analysis task for biomedical images, enabling the study of individual organelles, cells or organs. Deep learning has massively improved segmentation methods, but challenges remain in generalization to new…

Computer Vision and Pattern Recognition · Computer Science 2025-06-03 Carolin Teuber , Anwai Archit , Constantin Pape

The main challenges posed by the design of future Positron Emission Tomography machines are the improvement of the spatial and timing resolution and the combined operation with magnetic resonance. The Micro Pixel Photon Counter by Hamamatsu…

Medical Physics · Physics 2008-05-06 N. D'Ascenzo , E. Garutti , M. Goettlich , H. C. Schultz-Coulon , A. Tadday

In this paper we discuss a general approach to use SiPMs in different electrical configurations in combination with numerous scintillator materials for applications in nuclear instrumentation, such as calorimetry and timing. The "hybrid"…

Instrumentation and Detectors · Physics 2018-11-08 Lukas Nies , Hans-Georg Zaunick , Kai-Thomas Brinkmann

In positron emission tomography (PET), it is indispensable to perform attenuation correction in order to obtain the quantitatively accurate activity map (tracer distribution) in the body. Generally, this is carried out based on the…

Medical Physics · Physics 2025-10-16 Liyang Hu , Chong Chen

Geant4 simulations play a crucial role in the analysis and interpretation of experiments providing low energy precision tests of the Standard Model. This paper focuses on the accuracy of the description of the electron processes in the…

Instrumentation and Detectors · Physics 2013-08-23 G. Soti , F. Wauters , M. Breitenfeldt , P. Finlay , I. S. Kraev , A. Knecht , T. Porobic , D. Zákoucký , N. Severijns