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PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

Instrumentation and Detectors · Physics 2025-04-24 Stephan Naunheim , Luis Lopes de Paiva , Vanessa Nadig , Yannick Kuhl , Stefan Gundacker , Florian Mueller , Volkmar Schulz

The best measurement of the cosmic ray positron flux available today was performed by the HEAT balloon experiment more than 10 years ago. Given the limitations in weight and power consumption for balloon experiments, a novel approach was…

Astrophysics · Physics 2008-11-26 P. von Doetinchem , H. Gast , T. Kirn , G. Roper Yearwood , S. Schael

In recent years, demand for scintillation detectors with high time resolution (better than 100 ps) has emerged in high-energy physics and medical imaging applications. In particular, time of flight positron emission tomography (TOF-PET) can…

Instrumentation and Detectors · Physics 2022-09-14 V. S. Shevelev , A. V. Ishchenko , A. S. Vanetsev , V. Nagirnyi , S. I. Omelkov

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

Imaging with multiple modalities or multiple channels is becoming increasingly important for our modern society. A key tool for understanding and early diagnosis of cancer and dementia is PET-MR, a combined positron emission tomography and…

Image and Video Processing · Electrical Eng. & Systems 2020-07-24 Matthias J. Ehrhardt

Currently inorganic scintillator detectors are used in all commercial Time of Flight Positron Emission Tomograph (TOF-PET) devices. The J-PET collaboration investigates a possibility of construction of a PET scanner from plastic…

Positron emission tomography (PET) is an important modality for diagnosing diseases such as cancer and Alzheimer's disease, capable of revealing the uptake of radiolabeled molecules that target specific pathological markers of the diseases.…

Medical Physics · Physics 2025-01-17 Hsin-Hsiung Huang , Zheyuan Zhu , Slun Booppasiri , Zhuo Chen , Shuo Pang , Chien-Min Kao

We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the…

Medical Physics · Physics 2018-01-11 Zheng-Qian Ye , Ying-Guo Li , Tian-Quan Wang , Ya-Ming Fan , Yong-Zhi Yin , Xi-Meng Chen

There has been an increasing interest in the monitoring of nuclear fuel for power reactors by detecting the anti-neutrinos produced during operation. Small liquid scintillator detectors have already demonstrated sensitivity to operational…

Instrumentation and Detectors · Physics 2007-05-23 R. W. McKeown , D. E. Reyna

A new Digital Pulse Processing (DPP) module has been developed, based on a domino ring sampler version 4 chip (DRS4), with good time resolution for LaBr3 detectors, and different digital timing analysis methods for processing the raw…

Instrumentation and Detectors · Physics 2016-02-26 Cheng-Ming Du , Jin-Da Chen , Xiu-Ling Zhang , Hai-Bo Yang , Ke Cheng , Jie Kong , Zheng-Guo Hu , Zhi-Yu Sun , Hong Su , Hu-Shan Xu

The characteristics of the Solid-state Neutron Detector, under development for neutron-scattering measurements at the European Spallation Source, have been simulated with a Geant4-based computer code. The code models the interations of…

Spent nuclear fuel imaging before disposal is of utmost importance before long term disposal in dedicated storage facilities. Passive Gamma Emission Tomography (PGET) is an approved method by the International Atomic Energy Agency. The…

Tumor segmentation in medical imaging is crucial and relies on precise delineation. Fluorodeoxyglucose Positron-Emission Tomography (FDG-PET) is widely used in clinical practice to detect metabolically active tumors. However, FDG-PET scans…

Image and Video Processing · Electrical Eng. & Systems 2023-10-05 Matthias Hadlich , Zdravko Marinov , Rainer Stiefelhagen

In positron emission tomography acquisition (PET), sensitivity along a line of response can vary due to crystal geometrical arrangements in the scanner and/or detector inefficiencies, leading to severe artefacts in the reconstructed image.…

Depth-of-interaction (DOI) encoding is an effective strategy for reducing parallax error and preserving spatial resolution in positron emission tomography (PET), particularly in compact small-animal scanners. To enable efficient…

Medical Physics · Physics 2026-03-10 Satzhan Sitmukhambetov , Junwei Du , Mingwu Jin , Yujie Chi

Hyperion-IID is a positron emission tomography (PET) insert which allows simultaneous operation in a clinical magnetic resonance imaging (MRI) scanner. To read out the scintillation light of the employed LYSO crystal arrays with a pitch of…

Generating positron emission tomography (PET) images from computed tomography (CT) scans via deep learning offers a promising pathway to reduce radiation exposure and costs associated with PET imaging, improving patient care and…

Image and Video Processing · Electrical Eng. & Systems 2026-02-16 Valerio Guarrasi , Francesco Di Feola , Rebecca Restivo , Lorenzo Tronchin , Paolo Soda

In the present work we describe the design, construction, and testing of the optical prototype developed for the BOLDPET project, with the objective of creating a PET detection module with high spatial and time resolution. The BOLDPET…

PET provides in vivo molecular and functional imaging capability that is crucial to studying the interaction of plant with changing environment at the whole-plant level. We have developed a dedicated plant PET imager that features high…

Instrumentation and Detectors · Physics 2014-09-22 Qiang Wang , Aswin J. Mathews , Ke Li , Jie Wen , Sergey Komarov , Joseph A. O'Sullivan , Yuan-Chuan Tai