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Positron emission tomography (PET) is the most sensitive molecular imaging modality routinely applied in our modern healthcare. High radioactivity caused by the injected tracer dose is a major concern in PET imaging and limits its clinical…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Yuxin Xue , Yige Peng , Lei Bi , Dagan Feng , Jinman Kim

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET device built from plastic scintillators. It is a multi-purpose detector designed for medical imaging and for studies of properties of positronium atoms in porous matter…

A PET scanner based on silicon photomultipliers (SiPMs) has been widely used as an advanced nuclear medicine imaging technique that yields quantitative images of regional in vivo biology and biochemistry. The compact size of the SiPM allows…

Instrumentation and Detectors · Physics 2022-02-02 Cong Ma , Xiaokun Zhao , Size Gao , Fengping Zhang , Guocheng Wu , Xing Li , Lei Lu , Hongwei Ye , Hua Qian

Positron emission tomography (PET) imaging is widely used in a number of clinical applications, including cancer and Alzheimer's disease (AD) diagnosis, monitoring of disease development, and treatment effect evaluation. Statistical…

Tissues and Organs · Quantitative Biology 2025-11-07 Akhil Ambekar , Robert Zielinski , Ani Eloyan

The combination of plastic scintillators with Silicon Photo-Multipliers (SiPMs) is widely used for detecting radiation in high-energy astrophysics, particle physics, neutrino physics, or medical physics. An example of application for this…

Instrumentation and Methods for Astrophysics · Physics 2025-02-14 Nicolas De Angelis , Franck Cadoux , Coralie Husi , Merlin Kole , Sławomir Mianowski

J-PET is a photon detector built of plastic scintillators, which already has been commissioned for CPT studies in the decays of positronium. In the first experiment, J-PET has achieved a sensitivity to CPT violation at a level of 10^{-4},…

High Energy Physics - Phenomenology · Physics 2023-02-28 Neha Chug , Aleksander Gajos

The Jagiellonian Positron Emission Tomograph (J-PET) is the first PET built from plastic scintillators. J-PET prototype consists of 192 detection modules arranged axially in three layers forming a cylindrical diagnostic chamber with the…

We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…

Medical Physics · Physics 2009-11-11 Krzysztof Kacperski , Nicholas M. Spyrou

Positronium imaging was recently proposed to image the properties of positronium atoms in the patient body. Positronium properties depend on the size of intramolecular voids and oxygen concentration; therefore, they deliver information…

The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of…

Instrumentation and Detectors · Physics 2021-01-11 S. Enoch , A. Gola , P. Lecoq , A. Rivetti

In Particle and Nuclear Physics research and related applications, organic scintillators provide a cost-effective technology for the detection of ionising radiation. The next generation of experiments in this field is driving fundamental…

Instrumentation and Detectors · Physics 2024-07-31 P. Conde Muíño , J. A. Covas , A. Gomes , L. Gurriana , R. Machado , T. Martins , P. Mendes , R. Pedro , B. Pereira , A. J. Pontes , H. Wilkens

Time-Of-Flight (TOF) is a noble technique that is used in Positron Emission Tomography (PET) imaging worldwide. The scintillator based imaging system that is being used around the world for TOF-PET is very expensive. Multi-gap Resistive…

Instrumentation and Detectors · Physics 2018-07-02 Rajesh Ganai , Shaifali Mehta , Mehulkumar Shiroya , Mitali Mondal , Zubayer Ahammed , Subhasis Chattopadhyay

Positron emission tomography (PET) with 18F-Fluorodeoxyglucose (FDG) is an established tool in the diagnostic workup of patients with suspected dementing disorders. However, compared to the routinely available magnetic resonance imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Yitong Li , Ralph Buchert , Benita Schmitz-Koep , Timo Grimmer , Björn Ommer , Dennis M. Hedderich , Igor Yakushev , Christian Wachinger

Jagiellonian Positron Emission Tomograph (J-PET) is a multi-purpose detector which will be used for search for discrete symmetries violations in the decays of positronium atoms and for investigations with positronium atoms in life-sciences…

We proposed a new approach, which is inspired by the method of super-resolution (SR) structured illumination microscopy (SIM) for overcoming the resolution limit in microscopy due to diffraction of light, for increasing the resolution of…

Medical Physics · Physics 2026-02-04 Youdong Lang , Qingguo Xie , Chien-Min Kao

Over the last decade one of the most significant technological advances made in the field of radiation detectors for nuclear medicine was the development of Silicon Photomultipler (SiPM) sensors. At present a only small number of SiPM based…

Instrumentation and Detectors · Physics 2020-08-03 Jeremy M. C. Brown

Positron Emission Tomography (PET) is an important molecular imaging tool widely used in medicine. Traditional PET systems rely on complete detector rings for full angular coverage and reliable data collection. However, incomplete-ring PET…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Yeqi Fang , Rong Zhou

The J-PET detector, which consists of inexpensive plastic scintillators, has demonstrated its potential in the study of fundamental physics. In recent years, a prototype with 192 plastic scintillators arranged in 3 layers has been optimized…

The J-PET tomograph is constructed from plastic scintillator strips arranged axially in concentric cylindrical layers. It enables investigations of positronium decays by measurement of the time, position, polarization and energy deposited…

One of the most challenges in medical imaging is the lack of data. It is proven that classical data augmentation methods are useful but still limited due to the huge variation in images. Using generative adversarial networks (GAN) is a…

Image and Video Processing · Electrical Eng. & Systems 2021-04-16 Amine Amyar , Su Ruan , Pierre Vera , Pierre Decazes , Romain Modzelewski
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