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Liquid xenon offers several features, which make it suitable for applications in nuclear medicine, such as high scintillation yield and fast scintillation decay time. Moreover, being a continuous medium with a uniform response, liquid xenon…
Positron emission tomography (PET) is a well-established functional imaging technique for diagnosing brain disorders. However, PET's high costs and radiation exposure limit its widespread use. In contrast, magnetic resonance imaging (MRI)…
The fast scintillation decay time and the high scintillation yield of liquid xenon makes it an appropriate material for nuclear medicine. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of…
Liquid xenon time projection chambers offer a homogeneous detection medium with excellent intrinsic energy resolution, fast scintillation, and true three-dimensional position sensitivity, making them an attractive alternative to…
Radiation detection is vital for space, medical imaging, homeland security, and environmental monitoring applications. In the past, the Monte Carlo radiation transport toolkit, Geant4, has been employed to enable the effective development…
Time-of-Flight Positron Emission Tomography is a medical imaging technique, based on the detection of two back-to-back {\gamma}-photons generated from radiotracers injected in the body. Its limit is the ability of employed scintillation…
Positron emission tomography (PET) is widely used to assess metabolic activity, but its application is limited by the availability of radiotracers. 18F-labeled fluorodeoxyglucose (18F-FDG) is the most commonly used tracer but shows limited…
An explicit positronium (Ps) source model was implemented in Geant4 to provide direct event-level control over annihilation channel selection, decay timing, and photon emission topology. The implementation supports direct annihilation,…
An innovative particle detector that offers a compelling combination of cost-effectiveness and high accuracy is introduced. The detector features plastic scintillators paired with a sparse arrangement of SiPMs, strategically positioned…
Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…
This work aims at applying the theory of the component-based normalization for the Jagiellonian PET scanner, currently under development at the Jagiellonian University. In any Positron Emission Tomography acquisition, efficiency along a…
Carbon ion therapy have the ability to overcome the limitation of convertional radiotherapy due to its most energy deposition in selective depth, usually called Bragg peak, which results in increased biological effectiness. During carbon…
Positron Emission Tomography (PET) is a crucial tool in medical imaging, particularly for diagnosing diseases like cancer and Alzheimer's. The advent of Positronium Lifetime Imaging (PLI) has opened new avenues for assessing the tissue…
This paper presents a novel image reconstruction pipeline for three-gamma (3-{\gamma}) positron emission tomography (PET) aimed at improving spatial resolution and reducing noise in nuclear medicine; the proposed Direct3{\gamma} pipeline…
The influence of detector setup configuration and scintillator material choice on spectrum quality in Positron Annihilation Lifetime Spectroscopy (PALS) is fundamentally acknowledged primarily by empirical observation. However, this study…
Positron emission tomography/computed tomography (PET/CT) is essential in oncology, yet the rapid expansion of scanners has outpaced the availability of trained specialists, making automated PET/CT report generation (PETRG) increasingly…
A major strength of iterative algorithms used in positron emission tomography (PET) lies in their abilities to introduce precise models of the physics at play, which includes the statistical nature of the detection processes, and a detailed…
The purpose of the presented investigations is to design, construct and establish the characteristic performance of the Jagiellonian Positron Emission Mammography(J-PEM), being designed for the detection and diagnosis of breast cancer. Its…
Positron emission tomography (PET) is a cornerstone of modern radiology. The ability to detect cancer and metastases in whole body scans fundamentally changed cancer diagnosis and treatment. One of the main bottlenecks in the clinical…
The Jagiellonian Positron Emission Tomograph (J-PET) project carried out in the Institute of Physics of the Jagiellonian University is focused on construction and tests of the first prototype of PET scanner for medical diagnostic which…