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Related papers: Diffusion-based Radiotherapy Dose Prediction Guide…

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Radiation therapy is the primary method used to treat cancer in the clinic. Its goal is to deliver a precise dose to the planning target volume (PTV) while protecting the surrounding organs at risk (OARs). However, the traditional workflow…

Image and Video Processing · Electrical Eng. & Systems 2024-04-10 Tara Gheshlaghi , Shahabedin Nabavi , Samire Shirzadikia , Mohsen Ebrahimi Moghaddam , Nima Rostampour

Early detection through imaging and accurate diagnosis is crucial in mitigating the high mortality rate associated with breast cancer. However, locating tumors from low-resolution and high-noise medical images is extremely challenging.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Feiyan Feng , Tianyu Liu , Hong Wang , Jun Zhao , Wei Li , Yanshen Sun

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Qi Gao , Zhihao Chen , Dong Zeng , Junping Zhang , Jianhua Ma , Hongming Shan

Purpose: Radiation therapy treatment planning is a trial-and-error, often time-consuming process. An optimal dose distribution based on a specific anatomy can be predicted by pre-trained deep learning (DL) models. However, dose…

Medical Physics · Physics 2021-09-15 Jianhui Ma , Dan Nguyen , Ti Bai , Michael Folkerts , Xun Jia , Weiguo Lu , Linghong Zhou , Steve Jiang

Diffusion models generate data by learning to reverse a forward process, where samples are progressively perturbed with Gaussian noise according to a predefined noise schedule. From a geometric perspective, each noise schedule corresponds…

Image and Video Processing · Electrical Eng. & Systems 2025-10-21 Teng Zhang , Hongxu Jiang , Kuang Gong , Wei Shao

Recovering high-dimensional statistical structure from limited measurements is a fundamental challenge in hyperspectral imaging, where capturing full-resolution data is often infeasible due to sensor, bandwidth, or acquisition constraints.…

Image and Video Processing · Electrical Eng. & Systems 2025-08-01 Jonathan Monsalve , Kumar Vijay Mishra

In this study we performed a feasibility investigation on implementing a fast and accurate dose calculation based on a deep learning technique. A two dimensional (2D) fluence map was first converted into a three dimensional (3D) volume…

Medical Physics · Physics 2021-02-03 Jiawei Fan , Lei Xing , Peng Dong , Jiazhou Wang , Weigang Hu , Yong Yang

Recently, research on denoising diffusion models has expanded its application to the field of image restoration. Traditional diffusion-based image restoration methods utilize degraded images as conditional input to effectively guide the…

Computer Vision and Pattern Recognition · Computer Science 2024-10-25 Zhenning Shi , Haoshuai Zheng , Chen Xu , Changsheng Dong , Bin Pan , Xueshuo Xie , Along He , Tao Li , Huazhu Fu

Fast dose calculation is critical for online and real time adaptive therapy workflows. While modern physics-based dose algorithms must compromise accuracy to achieve low computation times, deep learning models can potentially perform dose…

Medical Physics · Physics 2023-07-19 Oscar Pastor-Serrano , Peng Dong , Charles Huang , Lei Xing , Zoltán Perkó

The distribution of absorbed dose in radionuclide therapy with Lu$^{177}$ can be approximated by convolving an image of the time-integrated activity distribution with a dose voxel kernel representing different tissue types. This fast but…

Machine Learning · Statistics 2026-03-25 Luciano Melodia

Deep learning-based automated diagnosis of lung cancer has emerged as a crucial advancement that enables healthcare professionals to detect and initiate treatment earlier. However, these models require extensive training datasets with…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Ashish Mittal , Pranav Rao , Manoj Tadepalli , Preetham Putha

Radiation therapy outcomes are decided by two key parameters, dose and timing, whose best values vary substantially across patients. This variability is especially critical in the treatment of brain cancer, where fractionated or staged…

Medical Physics · Physics 2025-06-24 Hao Peng , Steve Jiang , Robert Timmerman

Diffusion models (DMs) have emerged as powerful tools for modeling complex data distributions and generating realistic new samples. Over the years, advanced architectures and sampling methods have been developed to make these models…

Machine Learning · Computer Science 2025-12-11 Roi Benita , Michael Elad , Joseph Keshet

Diffusion Probabilistic Models (DPMs) are powerful generative models that have achieved unparalleled success in a number of generative tasks. In this work, we aim to build inductive biases into the training and sampling of diffusion models…

Machine Learning · Computer Science 2025-03-14 Thomas Jiralerspong , Berton Earnshaw , Jason Hartford , Yoshua Bengio , Luca Scimeca

Leveraging the visual priors of pre-trained text-to-image diffusion models offers a promising solution to enhance zero-shot generalization in dense prediction tasks. However, existing methods often uncritically use the original diffusion…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Jing He , Haodong Li , Wei Yin , Yixun Liang , Leheng Li , Kaiqiang Zhou , Hongbo Zhang , Bingbing Liu , Ying-Cong Chen

Score-based diffusion models are a recently developed framework for posterior sampling in Bayesian inverse problems with a state-of-the-art performance for severely ill-posed problems by leveraging a powerful prior distribution learned from…

While diffusion models can successfully generate data and make predictions, they are predominantly designed for static images. We propose an approach for efficiently training diffusion models for probabilistic spatiotemporal forecasting,…

Machine Learning · Computer Science 2023-10-12 Salva Rühling Cachay , Bo Zhao , Hailey Joren , Rose Yu

Previous raw image-based low-light image enhancement methods predominantly relied on feed-forward neural networks to learn deterministic mappings from low-light to normally-exposed images. However, they failed to capture critical…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Yufei Wang , Yi Yu , Wenhan Yang , Lanqing Guo , Lap-Pui Chau , Alex C. Kot , Bihan Wen

Predicting potential outcomes of interventions from observational data is crucial for decision-making in medicine, but the task is challenging due to the fundamental problem of causal inference. Existing methods are largely limited to point…

Machine Learning · Computer Science 2024-10-14 Yuchen Ma , Valentyn Melnychuk , Jonas Schweisthal , Stefan Feuerriegel

Diffusion models demonstrate remarkable capabilities in capturing complex data distributions and have achieved compelling results in many generative tasks. While they have recently been extended to dense prediction tasks such as depth…

Computer Vision and Pattern Recognition · Computer Science 2025-12-16 Haorui Ji , Taojun Lin , Hongdong Li