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This essay reviews some key concepts in mathematical epidemiology and examines the intersection of this field with related scientific disciplines, such as chemical reaction network theory and Lagrange-Hamilton geometry. Through a synthesis…

Dynamical Systems · Mathematics 2024-06-06 Florin Avram , Rim Adenane , Mircea Neagu

Compartmental equations are primary tools in disease spreading studies. Their predictions are accurate for large populations but disagree with empirical and simulated data for finite populations, where uncertainties become a relevant…

Populations and Evolution · Quantitative Biology 2018-07-18 GM Nakamura , ND Gomes , GC Cardoso , AS Martinez

The dynamics of ecological as well as chemical systems may depend on heterogeneous configurations. Heterogeneity in reaction-diffusion systems often increase modelling and simulating difficulties when non-linear effects are present. One…

Physics and Society · Physics 2019-08-27 Orlando Silva

This article focuses, in the context of epidemic models, on rare events that may possibly correspond to crisis situations from the perspective of Public Health. In general, no close analytic form for their occurrence probabilities is…

Applications · Statistics 2013-08-28 Stéphan Clémençon , Anthony Cousien , Miraine Dávila Felipe , Viet Chi Tran

This work aims to provide an approach to the macroscopic modeling and simulation of pedestrian flow, coupled with contagion spreading, towards numerical investigation of the effect of certain, macro-control measures on epidemics transport…

Populations and Evolution · Quantitative Biology 2024-11-26 A. I. Delis , N. Bekiaris-Liberis

Epidemic spreading often occurs in spatially heterogeneous environments, yet how quenched heterogeneity reshapes its onset and critical dynamics remains poorly understood. The diffusive epidemic process, a minimal reaction-diffusion model…

Statistical Mechanics · Physics 2026-03-24 Valentin Anfray , Hong-Yan Shih

The dynamics of pulse solutions in a bistable reaction-diffusion system are studied analytically by reducing partial differential equations (PDEs) to finite-dimensional ordinary differential equations (ODEs). For the reduction, we apply the…

Dynamical Systems · Mathematics 2019-07-24 Kei Nishi , Yasumasa Nishiura , Takashi Teramoto

Epidemic disease spreading is conventionally often modelled and analyzed by means of rate and diffusion equations, following the paradigms of well-controlled chemical reactions and diffusive dynamics in a test tube. Yet, serious worries…

Physics and Society · Physics 2023-01-03 Klaus Kroy

In this survey we report some recent results in the mathematical modeling of epidemic phenomena through the use of kinetic equations. We initially consider models of interaction between agents in which social characteristics play a key role…

Populations and Evolution · Quantitative Biology 2023-09-11 Giacomo Albi , Giulia Bertaglia , Walter Boscheri , Giacomo Dimarco , Lorenzo Pareschi , Giuseppe Toscani , Mattia Zanella

Predicting counterfactual distributions in complex dynamical systems is essential for scientific modeling and decision-making in domains such as public health and medicine. However, existing methods often rely on point estimates or purely…

Machine Learning · Computer Science 2025-09-15 Wenhao Mu , Zhi Cao , Mehmed Uludag , Alexander Rodríguez

Modeling the spread of COVID-19 is crucial for informing public health policy. All models for COVID-19 epidemiology rely on parameters describing the dynamics of the infection process. The meanings of epidemiological parameters like R_0,…

Other Quantitative Biology · Quantitative Biology 2020-07-13 Yinon M. Bar-On , Ron Sender , Avi I. Flamholz , Rob Phillips , Ron Milo

This paper gives direct derivations of the differential equations and likelihood formulas of diffusion models assuming only knowledge of Gaussian distributions. A VAE analysis derives both forward and backward stochastic differential…

Machine Learning · Computer Science 2023-03-07 David McAllester

Understanding the dynamics of wildfire is crucial for developing management and intervention strategies. Mathematical and computational models can be used to improve our understanding of wildfire processes and dynamics. This paper presents…

Dynamical Systems · Mathematics 2024-02-02 Cordula Reisch , Adrián Navas-Montilla , Ilhan Özgen-Xian

We have established a novel mathematical model that considers various aspects of the spreading of the virus, including, the transmission based on being in the latent period, environment to human transmission, governmental decisions, and…

Quantitative Methods · Quantitative Biology 2020-08-31 Kamran Soltani , Ghader Rezazadeh

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

This paper is concerned with the well-posedness of a diffusion-reaction system for a Susceptible-Exposed-Infected-Recovered (SEIR) mathematical model. This model is written in terms of four nonlinear partial differential equations with…

Analysis of PDEs · Mathematics 2023-07-26 Ferdinando Auricchio , Pierluigi Colli , Gianni Gilardi , Alessandro Reali , Elisabetta Rocca

The appearance of the coronavirus (COVID-19) in late 2019 has dominated the news in the last few months as it developed into a pandemic. In many mathematics and physics classrooms, instructors are using the time series of the number of…

Physics Education · Physics 2020-07-24 Paulo H. Acioli

The outbreak of COVID-19 in 2020 has led to a surge in interest in the mathematical modeling of infectious diseases. Such models are usually defined as compartmental models, in which the population under study is divided into compartments…

Populations and Evolution · Quantitative Biology 2021-02-16 Malú Grave , Alex Viguerie , Gabriel F. Barros , Alessandro Reali , Alvaro L. G. A. Coutinho

Pandemic outbreak creates a life threatening situation around the world and for a while it feels as if it slows down the world. A lot of effort is being taken to mitigate the spread of the pandemics. The main objective of this paper is to…

Populations and Evolution · Quantitative Biology 2020-10-06 Olivi Thykkoottathil James , Sinnu Susan Thomas

The interplay between disease spreading and personal risk perception is of key importance for modelling the spread of infectious diseases. We propose a planar system of ordinary differential equations (ODEs) to describe the co-evolution of…

Dynamical Systems · Mathematics 2023-05-09 Massimo A. Achterberg , Mattia Sensi
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