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We study the problem of estimating the origin of an epidemic outbreak -- given a contact network and a snapshot of epidemic spread at a certain time, determine the infection source. Finding the source is important in different contexts of…

Physics and Society · Physics 2014-11-20 Andrey Y. Lokhov , Marc Mézard , Hiroki Ohta , Lenka Zdeborová

When controlling an emerging outbreak of an infectious disease it is essential to know the key epidemiological parameters, such as the basic reproduction number $R_0$ and the control effort required to prevent a large outbreak. These…

Populations and Evolution · Quantitative Biology 2016-04-18 Pieter Trapman , Frank Ball , Jean-Stéphane Dhersin , Viet Chi Tran , Jacco Wallinga , Tom Britton

Case studies are a popular and noteworthy type of research study in software engineering, offering significant potential to impact industry practices by investigating phenomena in their natural contexts. This potential to reach a broad…

Software Engineering · Computer Science 2024-02-14 Sergio Rico

Infectious disease modeling is used to forecast epidemics and assess the effectiveness of intervention strategies. Although the core assumption of mass-action models of homogeneously mixed population is often implausible, they are…

Physics and Society · Physics 2024-08-29 Thien-Minh Le , Jukka-Pekka Onnela

Epidemic models study the spread of an undesired agent through a population, be it infectious diseases through a country, misinformation in online social media, or pests infesting a region. In combating these epidemics, we rely neither on…

This article reviews recent advances in addressing empirical identification issues in cross-country and country-level studies and their implications for the identification of the effectiveness and consequences of economic sanctions. I argue…

General Economics · Economics 2023-05-25 Francisco Rodríguez

The emergence of novel infectious agents presents challenges to statistical models of disease transmission. These challenges arise from limited, poor-quality data and an incomplete understanding of the agent. Moreover, outbreaks manifest…

Methodology · Statistics 2024-03-20 Jiasheng Shi , Jeffrey S. Morris , David M. Rubin , Jing Huang

As an emergent infectious disease outbreak unfolds, public health response is reliant on information on key epidemiological quantities, such as transmission potential and serial interval. Increasingly, transmission models fit to incidence…

Populations and Evolution · Quantitative Biology 2015-06-29 Aaron A. King , Matthieu Domenech de Cellès , Felicia M. G. Magpantay , Pejman Rohani

There has been much recent interest in modelling epidemics on networks, particularly in the presence of substantial clustering. Here, we develop pairwise methods to answer questions that are often addressed using epidemic models, in…

Populations and Evolution · Quantitative Biology 2010-12-10 Thomas House , Matt J Keeling

Evidence-based knowledge of infectious disease burden, including prevalence, incidence, severity and transmission, in different population strata and locations, and possibly in real time, is crucial to the planning and evaluation of public…

Methodology · Statistics 2018-08-14 Daniela De Angelis , Anne M. Presanis

Some epidemics have been empirically observed to exhibit outbreaks of all possible sizes, i.e., to be scalefree or scale-invariant. Different explanations for this finding have been put forward; among them there is a model for "accidental…

Biological Physics · Physics 2011-09-06 Oscar A. Pinto , Miguel A. Muñoz

Causal effects are commonly defined as comparisons of the potential outcomes under treatment and control, but this definition is threatened by the possibility that the treatment or control condition is not well-defined, existing instead in…

Methodology · Statistics 2019-04-26 Raiden B. Hasegawa , Sameer K. Deshpande , Dylan S. Small , Paul R. Rosenbaum

This review presents and reviews various solved and open problems in developing, analyzing, and mitigating epidemic spreading processes under human decision-making. We provide a review of a range of epidemic models and explain the pros and…

Systems and Control · Electrical Eng. & Systems 2021-12-10 Yunhan Huang , Quanyan Zhu

Advances in mathematical epidemiology have led to a better understanding of the risks posed by epidemic spreading and informed strategies to contain disease spread. However, a challenge that has been overlooked is that, as a disease becomes…

Physics and Society · Physics 2016-02-17 Lucas Böttcher , Olivia Woolley-Meza , Nuno A. M. Araújo , Hans J. Herrmann , Dirk Helbing

For obtaining causal inferences that are objective, and therefore have the best chance of revealing scientific truths, carefully designed and executed randomized experiments are generally considered to be the gold standard. Observational…

Applications · Statistics 2008-11-12 Donald B. Rubin

Diseases spread over temporal networks of interaction events between individuals. Structures of these temporal networks hold the keys to understanding epidemic propagation. One early concept of the literature to aid in discussing these…

Physics and Society · Physics 2021-06-07 Naoki Masuda , Joel C. Miller , Petter Holme

The Richards family models comprise a well-known set of models with useful parameters to describe several aspects of disease outbreaks. Some of these models have been used to study the current Covid-19 pandemic. However, there seems to be…

Populations and Evolution · Quantitative Biology 2020-07-09 Emiro A. Molina-Cuevas

Most traditional models of uncertainty have focused on the associational relationship among variables as captured by conditional dependence. In order to successfully manage intelligent systems for decision making, however, we must be able…

Artificial Intelligence · Computer Science 2015-05-19 David Heckerman , Ross D. Shachter

What is the difference of a prediction that is made with a causal model and a non-causal model? Suppose we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as…

Methodology · Statistics 2024-04-27 Jonas Peters , Peter Bühlmann , Nicolai Meinshausen

The paper presents an algorithm for syndromic surveillance of an epidemic outbreak formulated in the context of stochastic nonlinear filtering. The dynamics of the epidemic is modeled using a generalized compartmental epidemiological model…

Quantitative Methods · Quantitative Biology 2011-10-24 Alex Skvortsov , Branko Ristic
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