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Objective: To identify if whole-brain structural network alterations in patients with temporal lobe epilepsy (TLE) and focal to bilateral tonic-clonic seizures (FBTCS) differ from alterations in patients without FBTCS. Methods: We…

The hypothalamus plays an important role in the regulation of the bodys metabolic state and behaviors related to survival. Despite its importance however, many questions exist regarding the intrinsic and extrinsic connections of the…

Deep learning models perform best with abundant, high-quality labels, yet such conditions are rarely achievable in EEG-based emotion recognition. Electroencephalogram (EEG) signals are easily corrupted by artifacts and individual…

Machine Learning · Computer Science 2025-11-20 Hyo-Jeong Jang , Hye-Bin Shin , Kang Yin

Cortical visual impairment is amongst the key pathological causes of pediatric visual abnormalities predominantly resulting from hypoxic-ischemic brain injury. Such an injury results in profound visual impairments which severely impairs the…

Neurons and Cognition · Quantitative Biology 2019-04-12 Ali-Mohammad Kamali , Mohammad Javad Gholamzadeh , Seyedeh Zahra Mousavi , Maryam Vasaghi Gharamaleki , Mohammad Nami

Surface analysis of the cortex is ubiquitous in human neuroimaging with MRI, e.g., for cortical registration, parcellation, or thickness estimation. The convoluted cortical geometry requires isotropic scans (e.g., 1mm MPRAGEs) and good…

Image and Video Processing · Electrical Eng. & Systems 2023-05-04 Karthik Gopinath , Douglas N. Greve , Sudeshna Das , Steve Arnold , Colin Magdamo , Juan Eugenio Iglesias

Despite participants engaging in unimodal stimuli, such as watching images or silent videos, recent work has demonstrated that multi-modal Transformer models can predict visual brain activity impressively well, even with incongruent…

Neurons and Cognition · Quantitative Biology 2025-05-27 Subba Reddy Oota , Khushbu Pahwa , Mounika Marreddy , Maneesh Singh , Manish Gupta , Bapi S. Raju

This study aims to investigate topological organization of cortical thickness and functional networks by cortical lobes. First, I demonstrated modular organization of these networks by the cortical surface frontal, temporal, parietal and…

Neurons and Cognition · Quantitative Biology 2025-05-27 Vesna Vuksanović

Bipolar disorder is a mental disorder that causes periods of manic and depressive episodes. In this work, we classify recordings from Bipolar Disorder corpus that contain 7 different tasks, into hypomania, mania, and remission classes using…

Audio and Speech Processing · Electrical Eng. & Systems 2022-02-15 Pınar Baki , Heysem Kaya , Elvan Çiftçi , Hüseyin Güleç , Albert Ali Salah

Robust characterization of dynamic causal interactions in multivariate biomedical signals is essential for advancing computational and algorithmic methods in biomedical imaging. Conventional approaches, such as Dynamic Bayesian Networks…

Signal Processing · Electrical Eng. & Systems 2026-02-17 Farwa Abbas , Wei Dai , Zoran Cvetkovic , Verity McClelland

The neuroscience study has revealed the discrepancy of emotion expression between left and right hemispheres of human brain. Inspired by this study, in this paper, we propose a novel bi-hemispheric discrepancy model (BiHDM) to learn the…

Neurons and Cognition · Quantitative Biology 2019-06-06 Yang Li , Wenming Zheng , Lei Wang , Yuan Zong , Lei Qi , Zhen Cui , Tong Zhang , Tengfei Song

Alzheimer's disease (AD) is the most common type of dementia accompanied with brain atrophy. Structural measurements of brain atrophy in specific brain structures such as hippocampus using magnetic resonance imaging (MRI) have been reported…

Medical Physics · Physics 2016-05-10 Kenya Murase , Naohiko Gondo , Tsutomu Soma

Multivariate regression models for age estimation are a powerful tool for assessing abnormal brain morphology associated to neuropathology. Age prediction models are built on cohorts of healthy subjects and are built to reflect normal aging…

Computer Vision and Pattern Recognition · Computer Science 2018-04-05 Benjamin Gutierrez Becker , Tassilo Klein , Christian Wachinger

Recently there has been significant interest in measuring time-varying functional connectivity (TVC) between different brain regions using resting-state functional magnetic resonance imaging (rs-fMRI) data. One way to assess the…

Signal Processing · Electrical Eng. & Systems 2022-03-29 Hamed Honari , Martin A. Lindquist

Objectives: To examine sex differences in the associations between vascular risk factors and 6-year changes in the volume of white matter hyperintensities (WMH), and between changes in WMH volumes and changes in cognitive performance, in a…

Neurons and Cognition · Quantitative Biology 2023-07-19 Abdullah Alqarni , Wei Wen , Ben C. P. Lam , Nicole Kochan , Henry Brodaty , Perminder S. Sachdev , Jiyang Jiang

The early detection of Alzheimer's disease (AD) through widespread screening has emerged as a primary strategy to mitigate the significant global impact of AD. EEG measurements offer a promising solution for extensive AD detection. However,…

Signal Processing · Electrical Eng. & Systems 2025-05-22 Kevin Hung , Gary Man-Tat Man , Jincheng Wang

To minimize functional morbidity associated with brain surgery, new preventive approaches (also referred to as "prehabilitation") by using motor-imagery-based computer interfaces (MI-BCIs) can be utilized. To achieve successful MI-BCI…

Neurons and Cognition · Quantitative Biology 2017-08-03 Milena Korostenskaja , Christoph Kapeller , Ki H Lee , Christoph Guger , James Baumgartner , Eduardo M. Castillo

The assessment of consciousness and unconsciousness is a challenging issue in modern neuroscience. Consciousness is closely related to memory consolidation in that memory is a critical component of conscious experience. So far, many studies…

Signal Processing · Electrical Eng. & Systems 2020-05-19 Gi-Hwan Shin , Minji Lee , Seong-Whan Lee

Parkinsons disease (PD) alters cortical neural dynamics, yet reliable non-invasive electrophysiological biomarkers remain elusive. This study examined whether interpretable EEG features capturing complementary aspects of neural dynamics can…

Neurons and Cognition · Quantitative Biology 2026-04-14 Antonios G. Dougalis

Current neuroimaging studies on neurodegenerative diseases and psychological risk factors have been developed predominantly in non Hispanic White cohorts, with other populations markedly underrepresented. In this work, we construct directed…

Quantification of brain atrophy currently requires visual rating scales which are time consuming and automated brain image analysis is warranted. We validated our automated deep learning (DL) tool measuring the Global Cerebral Atrophy (GCA)…

Image and Video Processing · Electrical Eng. & Systems 2025-09-11 Sukhdeep Bal , Emma Colbourne , Jasmine Gan , Ludovica Griffanti , Taylor Hanayik , Nele Demeyere , Jim Davies , Sarah T Pendlebury , Mark Jenkinson