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Schizophrenia (SCZ), as a chronic and persistent disorder, exhibits working memory deficits across various stages of the disorder, yet the neural mechanisms underlying these deficits remain elusive with inconsistent neuroimaging findings.…

Neurons and Cognition · Quantitative Biology 2023-10-16 Yuhao Yao , Shufang Zhang , Boyao Wang , Gaofeng Zhao , Hong Deng , Ying Chen

Understanding the cortical organization of the human brain requires interpretable descriptors for distinct structural and functional imaging data. 3D polarized light imaging (3D-PLI) is an imaging modality for visualizing fiber architecture…

Computer Vision and Pattern Recognition · Computer Science 2024-09-04 Alexander Oberstrass , Jordan DeKraker , Nicola Palomero-Gallagher , Sascha E. A. Muenzing , Alan C. Evans , Markus Axer , Katrin Amunts , Timo Dickscheid

Numerous studies have established that estimated brain age, as derived from statistical models trained on healthy populations, constitutes a valuable biomarker that is predictive of cognitive decline and various neurological diseases. In…

Computer Vision and Pattern Recognition · Computer Science 2019-07-02 Xinyang Feng , Zachary C. Lipton , Jie Yang , Scott A. Small , Frank A. Provenzano

Bipolar disorder (BD) and borderline personality disorder (BPD) are two chronic mental health conditions that clinicians find challenging to distinguish based on clinical interviews, due to their overlapping symptoms. In this work, we…

Machine Learning · Computer Science 2022-01-02 Bo Wang , Yue Wu , Nemanja Vaci , Maria Liakata , Terry Lyons , Kate E A Saunders

Introduction: Identifying neurobiological differences between patients suffering from Major Depressive Disorder (MDD) and healthy individuals has been a mainstay of clinical neuroscience for decades. However, recent meta- and mega-analyses…

Cognitive diagnosis models have been widely used in different areas, especially intelligent education, to measure users' proficiency levels on knowledge concepts, based on which users can get personalized instructions. As the measurement is…

Computers and Society · Computer Science 2024-03-25 Fei Wang , Qi Liu , Enhong Chen , Chuanren Liu , Zhenya Huang , Jinze Wu , Shijin Wang

Normative models of brain structure estimate the effects of covariates such as age and sex using large samples of healthy controls. These models can then be applied to e.g. smaller clinical cohorts to distinguish disease effects from other…

There are reasons to suggest that a number of mental disorders may be related to alteration in the neural complexity (NC). Thus, quantitative analysis of NC could be helpful in classifying mental and understanding conditions. Here, focusing…

Neurons and Cognition · Quantitative Biology 2024-09-02 Dimitri Marques Abramov , Henrique Santos Lima , Vladimir Lazarev , Paulo Ricardo Galhanone , Constantino Tsallis

Resting-state brain functional connectivity quantifies the synchrony between activity patterns of different brain regions. In functional magnetic resonance imaging (fMRI), each region comprises a set of spatially contiguous voxels at which…

Methodology · Statistics 2025-11-07 Ruobin Liu , Chao Zhang , Chau Tran , Sophie Achard , Wendy Meiring , Alexander Petersen

Alzheimer's disease gradually affects several components including the cerebral dimension with brain atrophies, the cognitive dimension with a decline in various functions and the functional dimension with impairment in the daily living…

Functional MRI (fMRI) is widely used to examine brain functionality by detecting alteration in oxygenated blood flow that arises with brain activity. This work aims to investigate the neurological variation of human brain responses during…

Computer Vision and Pattern Recognition · Computer Science 2023-09-28 Naveen Kanigiri , Manohar Suggula , Debanjali Bhattacharya , Neelam Sinha

Recent studies proposed the use of Total Correlation to describe functional connectivity among brain regions as a multivariate alternative to conventional pair-wise measures such as correlation or mutual information. In this work we build…

Neurons and Cognition · Quantitative Biology 2022-11-28 Qiang Li , Greg Ver Steeg , Shujian Yu , Jesus Malo

This paper proposes a novel approach of integrating different neuroimaging techniques to characterize an autistic brain. Different techniques like EEG, fMRI and DTI have traditionally been used to find biomarkers for autism, but there have…

This study investigates the potential of multimodal data integration, which combines electroencephalogram (EEG) data with sociodemographic characteristics like age, sex, education, and intelligence quotient (IQ), to diagnose mental diseases…

Machine Learning · Computer Science 2025-02-07 Himanshi Singh , Sadhana Tiwari , Sonali Agarwal , Ritesh Chandra , Sanjay Kumar Sonbhadra , Vrijendra Singh

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

Neurons and Cognition · Quantitative Biology 2025-07-14 Sungwoo Ahn , Evie A. Malaia , Leonid L Rubchinsky

Bipolar disorder (BD) and schizophrenia (SZ) are severe mental disorders with profound societal impact. Identifying risk markers early is crucial for understanding disease progression and enabling preventive measures. The Danish High Risk…

Computer Vision and Pattern Recognition · Computer Science 2024-03-25 Vladyslav Zalevskyi , Kristoffer Hougaard Madsen

Previous research on the diagnosis of Bipolar disorder has mainly focused on resting-state functional magnetic resonance imaging. However, their accuracy can not meet the requirements of clinical diagnosis. Efficient multimodal fusion…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Guoxin Wang , Sheng Shi , Shan An , Fengmei Fan , Wenshu Ge , Qi Wang , Feng Yu , Zhiren Wang

Empirical studies over the past two decades have supported the hypothesis that schizophrenia is characterized by altered connectivity patterns in functional brain networks. These alterations have been proposed as genetically-mediated…

Neurons and Cognition · Quantitative Biology 2013-06-28 Felix Siebenhuhner , Shennan A. Weiss , Richard Coppola , Daniel R. Weinberger , Danielle S. Bassett

In recent years, there has been growing interest in studying cognitive distortions and emotional appraisals from both computational and psychological perspectives. Despite considerable similarities between emotional reappraisal and…

Computation and Language · Computer Science 2025-11-14 Navneet Agarwal , Kairit Sirts

Robust decoding and classification of brain patterns measured with electroencephalography (EEG) remains a major challenge for real-world (i.e. outside scientific lab and medical facilities) brain-computer interface (BCI) applications due to…

Neurons and Cognition · Quantitative Biology 2025-12-03 Paul Barbaste , Olivier Oullier , Xavier Vasques
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