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As the large amount of sequencing data accumulated in past decades and it is still accumulating, we need to handle the more and more sequencing data. As the fast development of the computing technologies, we now can handle a large amount of…

Other Quantitative Biology · Quantitative Biology 2021-01-05 Songting Shi

In this work, we propose a new particle-based variational inference (ParVI) method for accelerating the Energetic Variational Inference with Implicit scheme (EVI-Im) introduced in Ref. \cite{wang2021particle}. Inspired by energy…

Machine Learning · Statistics 2026-05-14 Xuelian Bao , Lulu Kang , Chun Liu , Yiwei Wang

Tackling pattern recognition problems in areas such as computer vision, bioinformatics, speech or text recognition is often done best by taking into account task-specific statistical relations between output variables. In structured…

Machine Learning · Statistics 2016-03-14 Rein Houthooft , Filip De Turck

Reasoning on large and complex real-world models is a computationally difficult task, yet one that is required for effective use of many AI applications. A plethora of inference algorithms have been developed that work well on specific…

Artificial Intelligence · Computer Science 2016-06-13 Avi Pfeffer , Brian Ruttenberg , William Kretschmer

Variational inference (VI) plays an essential role in approximate Bayesian inference due to its computational efficiency and broad applicability. Crucial to the performance of VI is the selection of the associated divergence measure, as VI…

Machine Learning · Computer Science 2021-06-24 Ruqi Zhang , Yingzhen Li , Christopher De Sa , Sam Devlin , Cheng Zhang

In this paper, we propose CI-VI an efficient and scalable solver for semi-implicit variational inference (SIVI). Our method, first, maps SIVI's evidence lower bound (ELBO) to a form involving a nonlinear functional nesting of expected…

Machine Learning · Computer Science 2021-01-18 Vincent Moens , Hang Ren , Alexandre Maraval , Rasul Tutunov , Jun Wang , Haitham Ammar

Stochastic natural gradient variational inference (NGVI) is a popular and efficient algorithm for Bayesian inference. Despite empirical success, the convergence of this method is still not fully understood. In this work, we define and study…

Methodology · Statistics 2026-04-02 Thomas Guilmeau , Hadrien Hendrikx , Florence Forbes

We propose stepwise variational inference (VI) with vine copulas: a universal VI procedure that combines vine copulas with a novel stepwise estimation procedure of the variational parameters. Vine copulas consist of a nested sequence of…

Machine Learning · Statistics 2026-03-25 Elisabeth Griesbauer , Leiv Rønneberg , Arnoldo Frigessi , Claudia Czado , Ingrid Hobæk Haff

Geoscientists use observed data to estimate properties of the Earth's interior. This often requires non-linear inverse problems to be solved and uncertainties to be estimated. Bayesian inference solves inverse problems under a probabilistic…

Geophysics · Physics 2024-01-01 Xuebin Zhao , Andrew Curtis

Semi-implicit variational inference (SIVI) enhances the expressiveness of variational families through hierarchical semi-implicit distributions, but the intractability of their densities makes standard ELBO-based optimization biased. Recent…

Machine Learning · Statistics 2026-01-21 Longlin Yu , Ziheng Cheng , Shiyue Zhang , Cheng Zhang

Variational inference (VI) is a popular approach in Bayesian inference, that looks for the best approximation of the posterior distribution within a parametric family, minimizing a loss that is typically the (reverse) Kullback-Leibler (KL)…

Machine Learning · Statistics 2025-11-18 Marguerite Petit-Talamon , Marc Lambert , Anna Korba

Inference networks of traditional Variational Autoencoders (VAEs) are typically amortized, resulting in relatively inaccurate posterior approximation compared to instance-wise variational optimization. Recent semi-amortized approaches were…

Machine Learning · Computer Science 2020-11-18 Minyoung Kim , Vladimir Pavlovic

This paper considers parameter estimation for nonlinear state-space models, which is an important but challenging problem. We address this challenge by employing a variational inference (VI) approach, which is a principled method that has…

Machine Learning · Statistics 2022-09-15 Jarrad Courts , Adrian Wills , Thomas Schön , Brett Ninness

Variational empirical Bayes (VEB) methods provide a practically attractive approach to fitting large, sparse, multiple regression models. These methods usually use coordinate ascent to optimize the variational objective function, an…

Methodology · Statistics 2024-11-25 Saikat Banerjee , Peter Carbonetto , Matthew Stephens

Variational inference approximates the posterior distribution of a probabilistic model with a parameterized density by maximizing a lower bound for the model evidence. Modern solutions fit a flexible approximation with stochastic gradient…

Machine Learning · Statistics 2017-07-13 Joseph Sakaya , Arto Klami

We provide the first convergence guarantee for full black-box variational inference (BBVI), also known as Monte Carlo variational inference. While preliminary investigations worked on simplified versions of BBVI (e.g., bounded domain,…

Machine Learning · Computer Science 2024-01-12 Kyurae Kim , Jisu Oh , Kaiwen Wu , Yi-An Ma , Jacob R. Gardner

Stochastic natural gradient variational inference (NGVI) is a popular posterior inference method with applications in various probabilistic models. Despite its wide usage, little is known about the non-asymptotic convergence rate in the…

Machine Learning · Computer Science 2024-06-05 Kaiwen Wu , Jacob R. Gardner

Several recent works have explored stochastic gradient methods for variational inference that exploit the geometry of the variational-parameter space. However, the theoretical properties of these methods are not well-understood and these…

Machine Learning · Statistics 2016-08-15 Mohammad Emtiyaz Khan , Reza Babanezhad , Wu Lin , Mark Schmidt , Masashi Sugiyama

Estimating a distribution given access to its unnormalized density is pivotal in Bayesian inference, where the posterior is generally known only up to an unknown normalizing constant. Variational inference and Markov chain Monte Carlo…

Machine Learning · Statistics 2025-05-06 Daniel Ward , Mark Beaumont , Matteo Fasiolo

Machine learning predictions are increasingly used to supplement incomplete or costly-to-measure outcomes in fields such as biomedical research, environmental science, and social science. However, treating predictions as ground truth…

Machine Learning · Statistics 2026-01-29 Yilin Song , Dan M. Kluger , Harsh Parikh , Tian Gu
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