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Larmor frequency shifts in white matter (WM) vary with fiber orientation due to anisotropic microstructure. Since clinical voxels are significantly larger than these microscopic frequency variations, the measured signal represents a bulk…

Accurate estimation of microscopic magnetic field variations induced in biological tissue can be valuable for mapping tissue composition in health and disease. Here, we present an extension to Quantitative susceptibility mapping (QSM) to…

This study aims to validate if MRI can measure anisotropic mesoscopic Larmor frequency shifts from white matter axonal microstructure relative to the B0 direction and if dMRI can estimate this anisotropy. Recent models describe how…

Medical Physics · Physics 2024-12-19 Anders Dyhr Sandgaard , Sune Nørhøj Jespersen

Purpose: To investigate the effect of anisotropic magnetic microstructure on the measurable Larmor frequency offset in media with heterogeneous magnetic susceptibility. Specific objectives were (i) validation of recently developed theory…

Soft Condensed Matter · Physics 2019-10-23 Alexander Ruh , Valerij G. Kiselev

We present a theoretical framework for the NMR and MRI measured Larmor frequency in media with magnetized microstructure using the mesoscopic Lorentz sphere and the principle of coarse graining. We obtain an analytical expression for…

Diffusion magnetic resonance imaging offers unique in vivo sensitivity to tissue microstructure in brain white matter, which undergoes significant changes during development and is compromised in virtually every neurological disorder. Yet,…

The Larmor frequency shift is found in porous media consisting of NMR-reporting fluid filling a connected pore within an NMR-invisible matrix for the case of fast diffusion in the fluid. The matrix material has a distinct…

Soft Condensed Matter · Physics 2019-02-20 Valerij G. Kiselev

Magnetic resonance imaging (MRI) is the method of choice for noninvasive studies of micrometer-scale structures in biological tissues via their effects on the time/frequency-dependent ("restricted") and anisotropic self-diffusion of water.…

Soft Condensed Matter · Physics 2021-11-16 Omar Narvaez , Maxime Yon , Hong Jiang , Diana Bernin , Eva Forssell-Aronsson , Alejandra Sierra , Daniel Topgaard

Estimating magnetic susceptibility using MRI depends on inverting a forward relationship between the susceptibility and measured Larmor frequency. However, an often-overlooked constraint in susceptibility fitting is that the Larmor…

The dynamic magnetic susceptibility of magnetic materials near ferromagnetic resonance (FMR) is very important in interpreting dc-voltage in electrical detection of FMR. Based on the causality principle and the assumption that the usual…

Mesoscale and Nanoscale Physics · Physics 2015-12-08 Yin Zhang , X. S. Wang , H. Y. Yuan , S. S. Kang , H. W. Zhang , X. R. Wang

In biological tissue, MR transverse relaxation stems from mechanisms spanning multiple scales, from molecular dipole-dipole interactions to mesoscopic field variations driven by tissue microstructure. While mesoscopic relaxation reflects…

Magnetic order and microwave absorption in amorphous ferromagnets and materials sintered from nanoscale ferromagnetic grains are investigated analytically and numerically within the random-anisotropy model. We show that a scaling argument…

Disordered Systems and Neural Networks · Physics 2023-11-14 Eugene M. Chudnovsky , Dmitry A. Garanin

Estimating intra- and extra-axonal microstructure parameters, such as volume fractions and diffusivities, has been one of the major efforts in brain microstructure imaging with MRI. The Standard Model (SM) of diffusion in white matter has…

The Global Magnetorotational Instability (MRI) is investigated for a configuration in which the rotation frequency changes only in a narrow transition region. If the vertical wavelength of the unstable mode is of the same order or smaller…

Instrumentation and Methods for Astrophysics · Physics 2011-02-11 J. Pino , S. M. Mahajan

The magnetoresistance (MR) of a material is typically insensitive to reversing the applied field direction and varies quadratically with magnetic field in the low-field limit. Quantum effects [1], unusual topological band structures [2],…

Biophysical modeling of diffusion MRI (dMRI) offers the exciting potential of bridging the gap between the macroscopic MRI resolution and microscopic cellular features, effectively turning the MRI scanner into a noninvasive in vivo…

We consider the NMR signal from a permeable medium with a heterogeneous Larmor frequency component that varies on a scale comparable to the spin-carrier diffusion length. We focus on the mesoscopic part of the transverse relaxation, that…

Mesoscale and Nanoscale Physics · Physics 2008-10-23 D. S. Novikov , V. G. Kiselev

Tissue microstructure has significance as a biomarker, however its accurate inference with diffusion magnetic resonance (MR) is still an open problem. With few exceptions, diffusion weighted (DW) MR models either process diffusion MR data…

Medical Physics · Physics 2019-08-20 Alpay Özcan

Diffusion-weighted MRI is the forerunner of the rapidly developed microstructural MRI aimed at in vivo evaluation of the cellular tissue architecture. This brief review focuses on the spatiotemporal scales of the microstructure that are…

Medical Physics · Physics 2020-08-14 Valerij G. Kiselev

\hspace{2mm} Diffusion-weighted magnetic resonance imaging (dMRI) of the brain offers unique capabilities including noninvasive probing of tissue microstructure and structural connectivity. It is widely used for clinical assessment of…

Image and Video Processing · Electrical Eng. & Systems 2025-12-30 Davood Karimi , Simon K. Warfield
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