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Randomized controlled trials (RCTs) have become powerful tools for assessing the impact of interventions and policies in many contexts. They are considered the gold standard for causal inference in the biomedical fields and many social…

Synaptic memory is considered to be the main element responsible for learning and cognition in humans. Although traditionally non-volatile long-term plasticity changes have been implemented in nanoelectronic synapses for neuromorphic…

Emerging Technologies · Computer Science 2017-12-20 Abhronil Sengupta , Kaushik Roy

Learning the dynamics of spatiotemporal events is a fundamental problem. Neural point processes enhance the expressivity of point process models with deep neural networks. However, most existing methods only consider temporal dynamics…

Machine Learning · Computer Science 2024-12-10 Zihao Zhou , Xingyi Yang , Ryan Rossi , Handong Zhao , Rose Yu

We explore the chaotic dynamics and complexity of a neuro-system with respect to variable synaptic weights in both noise free and noisy conditions. The chaotic dynamics of the system is investigated by bifurcation analysis and 0-1 test. A…

Chaotic Dynamics · Physics 2021-03-17 Sanjay K. Palit , Sayan Mukherjee

Synaptic plasticity, the dynamic tuning of signal transmission strength between neurons, serves as a fundamental basis for memory and learning in biological organisms. This adaptive nature of synapses is considered one of the key features…

Mesoscale and Nanoscale Physics · Physics 2024-11-11 Yechan Noh , Alex Smolyanitsky

Background: A therapeutic intervention in psychiatry can be viewed as an attempt to influence the brain's large-scale, dynamic network state transitions underlying cognition and behavior. Building on connectome-based graph analysis and…

The stochastic Hodgkin-Huxley neurons considered in this paper replace time-constant deterministic input $a dt$ of the classical deterministic model by increments $\vartheta dt + dX_t$ of a stochastic process: $X$ is Ornstein-Uhlenbeck with…

Probability · Mathematics 2023-06-22 Reinhard Höpfner

We report a detailed study of neuromorphic switching behaviour in inherently complex percolating networks of self-assembled metal nanoparticles. We show that variation of the strength and duration of the electric field applied to this…

Disordered Systems and Neural Networks · Physics 2019-03-06 S. K. Bose , S. Shirai , J. B. Mallinson , S. A. Brown

Serotonin (5-hydroxytryptamine) is a major neurotransmitter whose release from densely distributed serotonergic varicosities shapes plasticity and network integration throughout the brain, yet its extracellular dynamics remain poorly…

Tissues and Organs · Quantitative Biology 2026-05-21 Merlin Pelz , Skirmantas Janusonis , Gregory Handy

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

Health-related data is noisy and stochastic in implying the true physiological states of patients, limiting information contained in single-moment observations for sequential clinical decision making. We model patient-clinician interactions…

Artificial Intelligence · Computer Science 2019-05-21 Luchen Li , Matthieu Komorowski , Aldo A. Faisal

Decomposing multivariate time series with certain basic dynamics is crucial for understanding, predicting and controlling nonlinear spatiotemporally dynamic systems such as the brain. Dynamic mode decomposition (DMD) is a method for…

Signal Processing · Electrical Eng. & Systems 2025-07-15 Ryohei Fukuma , Yoshinobu Kawahara , Okito Yamashita , Kei Majima , Haruhiko Kishima , Takufumi Yanagisawa

Using computer simulations, we study a two-dimensional system of sterically interacting self-mobile run-and-tumble disk-shaped particles with an underlying periodic quasi-one-dimensional asymmetric substrate, and show that a rich variety of…

Soft Condensed Matter · Physics 2017-12-06 D. McDermott , C. J. Olson Reichhardt , C. Reichhardt

Nuclear quantum effects and non-Born--Oppenheimer effects play a vital role in many chemical and biological processes, motivating the incorporation of such effects into dynamical simulations. In real-time nuclear--electronic orbital…

Chemical Physics · Physics 2026-05-27 Nicholas J. Boyer , Sharon Hammes-Schiffer

Recurrent Neural Network models have elucidated the interplay between structure and dynamics in biological neural networks, particularly the emergence of irregular and rhythmic activities in cortex. However, most studies have focused on…

Neurons and Cognition · Quantitative Biology 2025-09-04 Nimrod Sherf , Xaq Pitkow , Krešimir Josić , Kevin E. Bassler

Digital health technologies (DHT), such as wearable devices, provide personalized, continuous, and real-time monitoring of patient. These technologies are contributing to the development of novel therapies and personalized medicine. Gaining…

Quantitative Methods · Quantitative Biology 2024-03-07 Samira Pakravan , Nikolaos Evangelou , Maxime Usdin , Logan Brooks , James Lu

The dynamical mechanism underlying the processes of anesthesia-induced loss of consciousness and recovery is key to gaining insights into the working of the nervous system. Previous experiments revealed an asymmetry between neural signals…

Neurons and Cognition · Quantitative Biology 2020-04-10 Chun-Wang Su , Liang Zheng , You-Jun Li , Hai-Jun Zhou , Jue Wang , Zi-Gang Huang , Ying-Cheng Lai

Attention-deficit/hyperactivity disorder (ADHD) is characterized by executive dysfunction and difficulties in processing emotional facial expressions, yet the large-scale neural dynamics underlying these impairments remain insufficiently…

Neurons and Cognition · Quantitative Biology 2025-12-16 Saghar Vosough , Gian Candrian , Johannes Kasper , Hossam Abdel Rehim , Dominique Eich , Andreas Mueller , Lutz Jäncke

We study external, electrical perturbations and their responses in the brain dynamic network of the \textit{Caenorhabditis elegans} soil worm, given by the connectome of its large somatic nervous system. Our analysis is inspired by a…

Neurons and Cognition · Quantitative Biology 2016-02-17 Chris G. Antonopoulos

We investigate memory effects and quantum transport in two-dimensional lattice systems within the framework of non-equilibrium Green's functions and Schwinger-Keldysh non-equilibrium quantum field theory. Starting from a 2D tight-binding…

Mesoscale and Nanoscale Physics · Physics 2026-05-29 Pragya Chaudhary