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We propose a machine learning based approach to accelerate quantum approximate optimization algorithm (QAOA) implementation which is a promising quantum-classical hybrid algorithm to prove the so-called quantum supremacy. In QAOA, a…

Emerging Technologies · Computer Science 2020-04-07 Mahabubul Alam , Abdullah Ash-Saki , Swaroop Ghosh

As edge applications using convolutional neural networks (CNN) models grow, it is becoming necessary to introduce dedicated hardware accelerators in which network parameters and feature-map data are represented with limited precision. In…

Neural and Evolutionary Computing · Computer Science 2018-11-01 Doyun Kim , Han Young Yim , Sanghyuck Ha , Changgwun Lee , Inyup Kang

We demonstrate the application of the Google Sycamore superconducting qubit quantum processor to combinatorial optimization problems with the quantum approximate optimization algorithm (QAOA). Like past QAOA experiments, we study…

This paper presents the Maximum Amplification Optimisation Algorithm (MAOA), a novel quantum algorithm designed for combinatorial optimisation in the restricted circuit depth context of near-term quantum computing. The MAOA first produces a…

Quantum Physics · Physics 2022-06-02 Tavis Bennett , Jingbo B. Wang

The quantum approximate optimisation ansatz (QAOA) is one of the flagship algorithms used to tackle combinatorial optimisation on graphs problems using a quantum computer, and is considered a strong candidate for early fault-tolerant…

Quantum Physics · Physics 2025-06-24 Yann Beaujeault-Taudière

Quantum computing has the potential to improve our ability to solve certain optimization problems that are computationally difficult for classical computers, by offering new algorithmic approaches that may provide speedups under specific…

Quantum Physics · Physics 2025-04-24 Ilya Tyagin , Marwa H. Farag , Kyle Sherbert , Karunya Shirali , Yuri Alexeev , Ilya Safro

In this work, we compare the performance of the Quantum Approximate Optimization Algorithm (QAOA) with state-of-the-art classical solvers such as Gurobi and MQLib to solve the combinatorial optimization problem MaxCut on 3-regular graphs.…

Quantum Physics · Physics 2024-05-01 Danylo Lykov , Jonathan Wurtz , Cody Poole , Mark Saffman , Tom Noel , Yuri Alexeev

The Genetic Algorithm is a heuristic that can be used to produce model independent solutions to an optimization problem, thus making it ideal for use in cosmology and more specifically in the analysis of type Ia supernovae data. In this…

Cosmology and Nongalactic Astrophysics · Physics 2011-03-18 Savvas Nesseris

This paper presents the implementation of a quantum sequence alignment (QSA) algorithm on biological data in environments simulating noisy intermediate-scale quantum (NISQ) computers. The approach to quantum bioinformatics adapts the…

Quantum Physics · Physics 2025-07-02 Floyd M. Creevey , Mingrui Jing , Lloyd C. L. Hollenberg

Quantum Support Vector Machines (QSVM) is one of the most promising frameworks in quantum machine learning, yet their performance depends on the design of the feature map. Conventional approaches rely on fixed quantum circuits, which often…

Quantum Physics · Physics 2025-11-25 Nguyen Minh Duc , Vu Tuan Hai , Le Bin Ho , Tran Nguyen Lan

Combinatorial optimization lies at the heart of numerous real-world applications. For a broad category of optimization problems, quantum computing is expected to exhibit quantum speed-up over classic computing. Among various quantum…

Quantum Physics · Physics 2025-09-23 Zixu Wang , Jack Mandell , Yangyang Xu , Jian Shi

Quantum annealing (QA) is a hardware-based heuristic optimization and sampling method applicable to discrete undirected graphical models. While similar to simulated annealing, QA relies on quantum, rather than thermal, effects to explore…

We consider a novel approach of measuring the homology of DNA sequences based of the variety of optimal alignments in the longest common subsequence sense. The proposed approach is compared with BLAST in measuring the homology of four…

Applications · Statistics 2012-10-16 Erik Hirmo , Jüri Lember , Heinrich Matzinger

A common approach to quantifying DNA involves repeated cycles of DNA amplification. This approach, employed by the polymerase chain reaction (PCR), produces outputs that are corrupted by amplification noise, making it challenging to…

Quantitative Methods · Quantitative Biology 2023-01-06 Abdoelnaser M Degoot , Wilfred Ndifon

Quantum approximate optimization algorithm (QAOA) aims to solve discrete optimization problems by sampling bitstrings using a parameterized quantum circuit. The circuit parameters (angles) are optimized in the way that minimizes the cost…

Quantum Physics · Physics 2023-11-29 A. Yu. Chernyavskiy , B. I. Bantysh , Yu. I. Bogdanov

Reconstructing DNA sequences without a reference, known as de novo assembly, is a complex computational task involving the alignment of overlapping fragments. To address this problem, a usual strategy is to map the assembly to a Quadratic…

De novo genome assembly is challenging in highly repetitive regions; however, reference-guided assemblers often suffer from bias. We propose a framework for pangenome-guided sequence assembly, which can resolve short-read data in complex…

Quantum Physics · Physics 2026-02-11 Josh Cudby , James Bonfield , Chenxi Zhou , Richard Durbin , Sergii Strelchuk

We use a genetic algorithm (GA) as a design aid for determining the optimal provisioning of entangled photon spectrum in flex-grid quantum networks with arbitrary numbers of channels and users. After introducing a general model for…

Quantum Physics · Physics 2022-06-24 J. Alnas , M. Alshowkan , N. S. V. Rao , N. A. Peters , J. M. Lukens

Channel estimation is of crucial importance for tomorrow's wireless mobile communication systems. This paper focuses on the solution of channel parameters estimation problem in a scenario involving multiple paths in the presence of additive…

Signal Processing · Electrical Eng. & Systems 2018-04-05 Amir Ebrahimi , Ardavan Rahimian

This paper presents a probabilistic approach for DNA sequence analysis. A DNA sequence consists of an arrangement of the four nucleotides A, C, T and G and different representation schemes are presented according to a probability measure…

Quantitative Methods · Quantitative Biology 2010-02-12 Amrita Priyam , B. M. Karan , G. Sahoo