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In this paper we propose a data-driven methodology to gain insight into the formation of different types of pseudopalisade structures. To this end, we start from a state of the art macroscopic model for the dynamics of GBM, that is coupled…

Analysis of PDEs · Mathematics 2025-08-12 Sandesh Athni Hiremath , Christina Surulescu

We make use of Kronecker structure for scaling Gaussian Process models to large-scale, heterogeneous, clinical data sets. Repeated measures, commonly performed in clinical research, facilitate computational acceleration for nonlinear…

Methodology · Statistics 2024-08-29 Owen Thomas , Leiv Rønneberg

Digital health interventions (DHIs) and remote patient monitoring (RPM) have shown great potential in improving chronic disease management through personalized care. However, barriers like limited efficacy and workload concerns hinder…

Machine Learning · Computer Science 2025-12-23 Johannes O. Ferstad , Emily B. Fox , David Scheinker , Ramesh Johari

Distributed Port-Hamiltonian (dPHS) theory provides a powerful framework for modeling physical systems governed by partial differential equations and has enabled a broad class of boundary control methodologies. Their effectiveness, however,…

Systems and Control · Electrical Eng. & Systems 2026-04-07 Thomas Beckers , Leonardo Colombo

The hematopoietic system has a highly regulated and complex structure in which cells are organized to successfully create and maintain new blood cells. Feedback regulation is crucial to tightly control this system, but the specific…

This article develops Probabilistic Hybrid Action Models (PHAMs), a realistic causal model for predicting the behavior generated by modern percept-driven robot plans. PHAMs represent aspects of robot behavior that cannot be represented by…

Artificial Intelligence · Computer Science 2011-09-29 M. Beetz , H. Grosskreutz

Out-of-distribution (OOD) detection aims to detect testing samples far away from the in-distribution (ID) training data, which is crucial for the safe deployment of machine learning models in the real world. Distance-based OOD detection…

Machine Learning · Computer Science 2024-02-06 Haodong Lu , Dong Gong , Shuo Wang , Jason Xue , Lina Yao , Kristen Moore

Port-Hamiltonian theory is an established way to describe nonlinear physical systems widely used in various fields such as robotics, energy management, and mechanical engineering. This has led to considerable research interest in the…

Systems and Control · Electrical Eng. & Systems 2023-09-12 Thomas Beckers

Randomized clinical trials eliminate confounding but impose strict exclusion criteria that limit recruitment to a subset of the population. Observational datasets are more inclusive but suffer from confounding -- often providing overly…

Machine Learning · Statistics 2022-10-31 Eric V. Strobl , Thomas A. Lasko

Estimating how a treatment affects different individuals, known as heterogeneous treatment effect estimation, is an important problem in empirical sciences. In the last few years, there has been a considerable interest in adapting machine…

Machine Learning · Computer Science 2024-10-18 Christopher Tran , Keith Burghardt , Kristina Lerman , Elena Zheleva

This paper presents a scenario-based model predictive control (MPC) scheme designed to control an evolving pandemic via non-pharmaceutical intervention (NPIs). The proposed approach combines predictions of possible pandemic evolution to…

Systems and Control · Electrical Eng. & Systems 2025-06-24 Domagoj Herceg , Marco DellOro , Riccardo Bertollo , Fuminari Miura , Paul de Klaver , Valentina Breschi , Dinesh Krishnamoorthy , Mauro Salazar

Developing models and algorithms to predict nonstationary time series is a long standing statistical problem. It is crucial for many applications, in particular for fashion or retail industries, to make optimal inventory decisions and avoid…

Signal Processing · Electrical Eng. & Systems 2023-09-12 Etienne David , Jean Bellot , Sylvain Le Corff

Background modelling is one of the main challenges in particle physics data analysis. Commonly employed strategies include the use of simulated events of the background processes, and the fitting of parametric background models to the…

High Energy Physics - Experiment · Physics 2022-10-19 A. Chisholm , T. Neep , K. Nikolopoulos , R. Owen , E. Reynolds , J. Silva

Given data on the choices made by consumers for different offer sets, a key challenge is to develop parsimonious models that describe and predict consumer choice behavior while being amenable to prescriptive tasks such as pricing and…

Machine Learning · Statistics 2025-04-15 Yanqiu Ruan , Xiaobo Li , Karthyek Murthy , Karthik Natarajan

We propose a novel federated learning paradigm to model data variability among heterogeneous clients in multi-centric studies. Our method is expressed through a hierarchical Bayesian latent variable model, where client-specific parameters…

Machine Learning · Computer Science 2023-06-29 Irene Balelli , Santiago Silva , Marco Lorenzi

Basket trials in oncology enroll multiple patients with cancer harboring identical gene alterations and evaluate their response to targeted therapies across cancer types. Several existing methods have extended a Bayesian hierarchical model…

Methodology · Statistics 2024-12-17 Ryo Kitabayashi , Hiroyuki Sato , Akihiro Hirakawa

Scientific analysis often relies on the ability to make accurate predictions of a system's dynamics. Mechanistic models, parameterized by a number of unknown parameters, are often used for this purpose. Accurate estimation of the model…

Dynamical Systems · Mathematics 2017-11-01 Franz Hamilton , Alun Lloyd , Kevin Flores

The use of supervised learning for Human Activity Recognition (HAR) on mobile devices leads to strong classification performances. Such an approach, however, requires large amounts of labeled data, both for the initial training of the…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Riccardo Presotto , Sannara Ek , Gabriele Civitarese , François Portet , Philippe Lalanda , Claudio Bettini

Suppose we are interested in the effect of a treatment in a clinical trial. The efficiency of inference may be limited due to small sample size. However, external control data are often available from historical studies. Motivated by an…

Methodology · Statistics 2021-12-10 Xinyu Li , Wang Miao , Fang Lu , Xiao-Hua Zhou

We continue studies of the uncertainty quantification problem in emission tomographies such as PET or SPECT when additional multimodal data (e.g., anatomical MRI images) are available. To solve the aforementioned problem we adapt the…

Machine Learning · Statistics 2021-12-03 Fedor Goncharov , Éric Barat , Thomas Dautremer
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