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This master thesis presents a new type of Positron Emission TOF Apparatus using Liquid xenOn (PETALO). The detector is based in the Liquid Xenon Scintillating Cell (LXSC). The cell is a box filled with liquid xenon (LXe) whose transverse…

Medical Physics · Physics 2016-06-01 J. M. Benlloch-Rodriguez

The time-consuming task of manual segmentation challenges routine systematic quantification of disease burden. Convolutional neural networks (CNNs) hold significant promise to reliably identify locations and boundaries of tumors from PET…

The purpose of the presented research is estimation of the performance characteristics of the economic Total-Body Jagiellonian-PET system (TB-J-PET) constructed from plastic scintillators. The characteristics are estimated according to the…

Semiconductor pixel detectors offer features for the detection of radiation which are interesting for particle physics detectors as well as for imaging e.g. in biomedical applications (radiography, autoradiography, protein crystallography)…

High Energy Physics - Experiment · Physics 2009-11-07 Norbert Wermes

We are investigating a prototype virtual pinhole positron emission tomography (VP-PET) system for small animal imaging applications. The PET detector modules were made up of 1.3 mm lutetium-yttrium oxyorthosilicate (LYSO) arrays, and the…

Medical Physics · Physics 2018-01-11 Zheng-Qian Ye , Ying-Guo Li , Tian-Quan Wang , Ya-Ming Fan , Yong-Zhi Yin , Xi-Meng Chen

In the domain of computer vision, Parameter-Efficient Tuning (PET) is increasingly replacing the traditional paradigm of pre-training followed by full fine-tuning. PET is particularly favored for its effectiveness in large foundation…

Computer Vision and Pattern Recognition · Computer Science 2025-01-16 Jiaqi Huang , Zunnan Xu , Ting Liu , Yong Liu , Haonan Han , Kehong Yuan , Xiu Li

Our understanding of organs at risk is progressing to include physical small tissues such as coronary arteries and the radiosensitivities of many small organs and tissues are high. Therefore, the accurate segmentation of small volumes in…

Image and Video Processing · Electrical Eng. & Systems 2024-04-08 Jianxin Zhou , Kadishe Fejza , Massimiliano Salvatori , Daniele Della Latta , Gregory M. Hermann , Angela Di Fulvio

To obtain high-quality positron emission tomography (PET) while minimizing radiation exposure, a range of methods have been designed to reconstruct standard-dose PET (SPET) from corresponding low-dose PET (LPET) images. However, most…

Image and Video Processing · Electrical Eng. & Systems 2024-04-11 Yuchen Fei , Yanmei Luo , Yan Wang , Jiaqi Cui , Yuanyuan Xu , Jiliu Zhou , Dinggang Shen

This paper presents a small-area monolithic pixel detector ASIC designed in 130 nm SiGe BiCMOS technology for the upgrade of the pre-shower detector of the FASER experiment at CERN. The purpose of this prototype is to study the integration…

All of the present methods for calibration and monitoring of TOF-PET scanner detectors utilize radioactive isotopes such as e.g. $^{22}$Na or $^{68}$Ge, which are placed or rotate inside the scanner. In this article we describe a novel…

Automated segmentation can assist radiotherapy treatment planning by saving manual contouring efforts and reducing intra-observer and inter-observer variations. The recent development of deep learning approaches has revoluted medical data…

Computer Vision and Pattern Recognition · Computer Science 2021-09-14 Zhuangzhuang Zhang , Tianyu Zhao , Hiram Gay , Baozhou Sun , Weixiong Zhang

We developed a beam telescope system comprising five layers of 300-$\mu$m-thick INTPIX4NA monolithic pixel sensors with each pixel size of 17 $\mu$m square. The sensors were fabricated using silicon-on-insulator (SOI) technology. The…

Instrumentation and Detectors · Physics 2022-08-24 Hisanori Suzuki , Takumi Omori , Kazuhiko Hara , Hiroki Yamauchi , Miho Yamada , Toru Tsuboyama , Ayaki Takeda

Positron Emission Mammography (PEM) imaging systems with the ability in detection of millimeter-sized tumors were developed in recent years. And some of them have been well used in clinical applications. In consideration of biopsy…

Medical Physics · Physics 2016-08-03 Xiao-Yue Gu , Wei Zhou , Lin Li , Peng-Fei Yin , Lei-Min Shang , Ming-Kai Yun , Zhen-Rui Lu , Xian-Chao Huang , Long Wei

We have recently introduced the idea of making use of three-photon positron annihilations in positron emission tomography. In this paper the basic characteristics of the three-gamma imaging in PET are studied by means of Monte Carlo…

Medical Physics · Physics 2009-11-11 Krzysztof Kacperski , Nicholas M. Spyrou

Purpose: HDR brachytherapy is a widely adopted modality for cancer treatment. However, it is not free from error and uncertainty. In-vivo dosimetry (IVD) is the only technique that can confirm correct dose delivery. This study details and…

Medical Physics · Physics 2025-12-10 Chahrazed Ghannoudi , Marie-Claude Lavallee , Benjamin Cote , Luc Beaulieu

The direct detection of binary systems in wide-field surveys is limited by the size of the stars' point-spread-functions (PSFs). A search for elongated objects can find closer companions, but is limited by the precision to which the PSF…

The NeuLAND (New Large-Area Neutron Detector) plastic-scintillator-based time-of-flight detector for 0.1-1.6 GeV neutrons is currently under construction at the Facility for Antiproton and Ion Research (FAIR), Darmstadt, Germany. In its…

Instrumentation and Detectors · Physics 2023-01-11 Thomas Hensel , David Weinberger , Daniel Bemmerer , Konstanze Boretzky , Igor Gašparić , Daniel Stach , Andreas Wagner , Kai Zuber

In this study, we have developed a new sub-MeV neutron detector that has a high position resolution, energy resolution, directional sensitivity, and low background. The detector is based on a super-fine-grained nuclear emulsion, called the…

Instrumentation and Detectors · Physics 2022-09-01 T. Shiraishi , I. Todoroki , T. Naka , A. Umemoto , R. Kobayashi , O. Sato

Positron Emission Tomography scan images are extensively used in radiotherapy planning, clinical diagnosis, assessment of growth and treatment of a tumor. These all rely on fidelity and speed of detection and delineation algorithm. Despite…

Medical Physics · Physics 2017-10-25 Yeman B. Hagos , Vu H. Minh , Saed Khawaldeh , Usama Pervaiz , Tajwar A. Aleef