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In this work, we adapt the epidemiological SIR model to study the evolution of the dissemination of COVID-19 in Germany and Brazil (nationally, in the State of Paraiba, and in the City of Campina Grande). We prove the well posedness and the…

Populations and Evolution · Quantitative Biology 2022-04-20 Adriano A. Batista , Severino Horácio da Silva

The viral load is known to be a chief predictor of the risk of transmission of infectious diseases. In this work, we investigate the role of the individuals' viral load in the disease transmission by proposing a new…

Adaptation and Self-Organizing Systems · Physics 2023-03-29 Rossella Della Marca , Nadia Loy , Andrea Tosin

The outbreak of Coronavirus Disease 2019 (COVID-19) is an ongoing pandemic affecting over 200 countries and regions. Inference about the transmission dynamics of COVID-19 can provide important insights into the speed of disease spread and…

Methodology · Statistics 2020-07-06 Tianjian Zhou , Yuan Ji

We study a discrete Susceptible-Infected-Recovered (SIR) model for the spread of infectious disease on a homogeneous tree and the limit behavior of the model in the case when the tree vertex degree tends to infinity. We obtain the…

Probability · Mathematics 2022-07-08 Alexander Gairat , Vadim Shcherbakov

We propose a multivariate GARCH model for non-stationary health time series by modifying the variance of the observations of the standard state space model. The proposed model provides an intuitive way of dealing with heteroskedastic data…

Methodology · Statistics 2023-03-16 Zayd Omar , David A. Stephens , Alexandra M. Schmidt , David L. Buckeridge

The SIR-compartment model is among the simplest models that describe the spread of a disease through a population. The model makes the unrealistic assumption that the population through which the disease is spreading is well-mixed. Although…

Populations and Evolution · Quantitative Biology 2022-11-16 Ryan Wilkinson , Marcus Roper

Recent years have seen a large amount of interest in epidemics on networks as a way of representing the complex structure of contacts capable of spreading infections through the modern human population. The configuration model is a popular…

Populations and Evolution · Quantitative Biology 2017-01-23 Frank Ball , Thomas House

Identifiability is the property in mathematical modelling that determines if model parameters can be uniquely estimated from data. For infectious disease models, failure to ensure identifiability can lead to misleading parameter estimates…

Methodology · Statistics 2025-06-10 Fanny Bergström , Martina Favero , Tom Britton

This study investigates the utilization of various mathematical models for comprehending and managing outbreaks of infectious diseases, with a specific focus on how different distributions of incubation times influence predictions regarding…

Adaptation and Self-Organizing Systems · Physics 2024-03-08 Eric Rozan , Marcelo N Kuperman , Sebastian Bouzat

We consider a stochastic Susceptible-Exposed-Infected-Recovered (SEIR) epidemiological model with a contact rate that fluctuates seasonally. Through the use of a nonlinear, stochastic projection, we are able to analytically determine the…

Populations and Evolution · Quantitative Biology 2013-09-11 Eric Forgoston , Ira B. Schwartz

Background. Health economic evaluations of interventions against infectious diseases are commonly based on the predictions of ordinary differential equation (ODE) systems or Markov models (MMs). Standard MMs are static, whereas ODE systems…

Methodology · Statistics 2018-09-05 Katrin Haeussler , Ardo van den Hout , Gianluca Baio

This paper focuses on the analysis of a stochastic SAIRS-type epidemic model that explicitly incorporates the roles of asymptomatic and symptomatic infectious individuals in disease transmission dynamics. Asymptomatic carriers, often…

Populations and Evolution · Quantitative Biology 2025-01-14 Brahim Boukanjime , Mohamed El Fatini , Mohamed Maama

We investigate the application of a framework for sparse model identification of differential equations from timeseries data in the context of compartmental models in epidemiology. Such frameworks often seek a sparse representation from a…

Optimization and Control · Mathematics 2025-10-23 Manuchehr Aminian , Kristin M. Kurianski

This paper deals with inference and prediction for multiple correlated time series, where one has also the choice of using a candidate pool of contemporaneous predictors for each target series. Starting with a structural model for the…

Machine Learning · Statistics 2018-09-20 S. Rao Jammalamadaka , Jinwen Qiu , Ning Ning

We present a class of SEIR Markov chain models for infectious diseases observed over discrete time in a random human population living in a closed environment. The population changes over time through random births, deaths, and transitions…

Populations and Evolution · Quantitative Biology 2019-07-30 Divine Wanduku , Chinmoy Rahul

Most epidemic processes on networks can be modelled by a compartmental model, that specifies the spread of a disease in a population. The corresponding compartmental graph describes how the viral state of the nodes (individuals) changes…

Physics and Society · Physics 2023-11-29 Massimo A. Achterberg , Piet Van Mieghem

We consider a Susceptible-Infective-Recovered (SIR) model, where the mechanism for the renewal of susceptibles is demographic, on a ring with next nearest neighbour interactions, and a family of correlated pair approximations (CPA),…

Populations and Evolution · Quantitative Biology 2013-06-04 Jerome Benoit , Ana Nunes , Margarida Telo da Gama

We study the spread of susceptible-infected-recovered (SIR) infectious diseases where an individual's infectiousness and probability of recovery depend on his/her "age" of infection. We focus first on early outbreak stages when stochastic…

Populations and Evolution · Quantitative Biology 2009-05-14 Joel Miller , Bahman Davoudi , Rafael Meza , Anja Slim , Babak Pourbohloul

We present three data driven model-types for COVID-19 with a minimal number of parameters to provide insights into the spread of the disease that may be used for developing policy responses. The first is exponential growth, widely studied…

Populations and Evolution · Quantitative Biology 2022-05-25 Andrea L. Bertozzi , Elisa Franco , George Mohler , Martin B. Short , Daniel Sledge

Pattern formation in biological tissues plays an important role in the development of living organisms. Since the classical work of Alan Turing, a pre-eminent way of modelling has been through reaction-diffusion mechanisms. More recently,…

Analysis of PDEs · Mathematics 2023-01-27 Alexey Kazarnikov , Robert Scheichl , Heikki Haario , Anna Marciniak-Czochra