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One way to study the spread of disease is through mathematical models. The most successful models compartmentalize the host population according to their infectious stage, e.g., susceptible (S), infected (I), exposed (E), and recovered (R).…

Populations and Evolution · Quantitative Biology 2024-09-25 Enrique C. Gabrick , Ervin K. Lenzi , Antonio M. Batista

The Susceptible-Infectious-Recovered (SIR) model is the canonical model of epidemics of infections that make people immune upon recovery. Many of the open questions in computational epidemiology concern the underlying contact structure's…

Physics and Society · Physics 2021-06-09 Petter Holme

A novel predictive modeling framework for the spread of infectious diseases using high dimensional partial differential equations is developed and implemented. A scalar function representing the infected population is defined on a…

Populations and Evolution · Quantitative Biology 2020-07-06 Sashikumaar Ganesan , Deepak Subramani

To be fully useful for public health practice, models for epidemic response must be able to do more than predict -- it is also important to incorporate the mechanisms underlying transmission dynamics to enable policymakers and practitioners…

Quantitative Methods · Quantitative Biology 2025-05-26 Jiale Tan , Marisa C. Eisenberg

A generalisation of the Susceptible-Infectious model is made to include a time-dependent transmission rate, which leads to a close analytical expression in terms of a logistic function. The solution can be applied to any continuous function…

Physics and Society · Physics 2020-10-08 L. Arturo Urena-Lopez , Alma X. Gonzalez-Morales

In this study, a new and natural way of constructing a stochastic Susceptible-Infected-Susceptible (SIS) model is proposed. This approach is natural in the sense that the disease transmission rate, $\beta$, is substituted with a generic,…

Probability · Mathematics 2025-11-07 Berk Tan Perçin

We introduce an epidemic model with varying infectivity and general exposed and infectious periods, where the infectivity of each individual is a random function of the elapsed time since infection, those function being i.i.d. for the…

Probability · Mathematics 2021-06-01 Raphael Forien , Guodong Pang , Etienne Pardoux

We have derived the governing equations for an SIR model with delay terms in both the infectivity and recovery of the disease. The equations are derived by modelling the dynamics as a continuous time random walk, where individuals move…

Dynamical Systems · Mathematics 2024-10-14 Christopher N. Angstmann , Stuart-James M. Burney , Anna V. McGann , Zhuang Xu

We have designed a computational model of a virus spread near the outbreak threshold. Using computer simulation we studied the Susceptible - Infected - Recovered (SIR) process where in consequence of a force of habit that is manifested by…

Populations and Evolution · Quantitative Biology 2021-12-23 Jozef Černák

The effect of spatial correlations on the spread of infectious diseases was investigated using a stochastic SIR (Susceptible-Infective-Recovered) model on complex networks. It was found that in addition to the reduction of the effective…

Populations and Evolution · Quantitative Biology 2007-05-23 J. Verdasca , M. M. Telo da Gama , A. Nunes , N. R. Bernardino , J. M. Pacheco , M. C. Gomes

1. Understanding the mechanisms underlying biological systems, and ultimately, predicting their behaviours in a changing environment requires overcoming the gap between mathematical models and experimental or observational data.…

Quantitative Methods · Quantitative Biology 2017-04-19 Philipp H Boersch-Supan , Sadie J Ryan , Leah R Johnson

Fractional-order SIR models have become increasingly popular in the literature in recent years, however unlike the standard SIR model, they often lack a derivation from an underlying stochastic process. Here we derive a fractional-order…

Populations and Evolution · Quantitative Biology 2016-03-31 Christopher N Angstmann , Bruce I Henry , Anna V McGann

A standard model for epidemics is the SIR model on a graph. We introduce a simple algorithm that uses the early infection times from a sample path of the SIR model to estimate the parameters this model, and we provide a performance…

Information Theory · Computer Science 2020-08-11 Charles Clum , Dustin G. Mixon

This paper describes the Bayesian SIR modeling of the 3 waves of Covid-19 in two contrasting US states during 2020-2021. A variety of models are evaluated at the county level for goodness-of-fit and an assessment of confounding predictors…

Applications · Statistics 2023-01-11 Andrew B Lawson , Joanne Kim

Multi-state models are frequently applied for representing processes evolving through a discrete set of state. Important classes of multi-state models arise when transitions between states may depend on the time since entry into the current…

Methodology · Statistics 2022-02-28 Rosario Barone , Andrea Tancredi

We introduce a modified SIR model with memory for the dynamics of epidemic spreading in a constant population of individuals. Each individual is in one of the states susceptible (${\bf S}$), infected (${\bf I}$) or recovered (${\bf R}$). In…

Populations and Evolution · Quantitative Biology 2022-03-03 Michael Bestehorn , Thomas M. Michelitsch , Bernard A. Collet , Alejandro P. Riascos , Andrzej F. Nowakowski

We describe the population-based SEIR (susceptible, exposed, infected, removed) model developed by the Irish Epidemiological Modelling Advisory Group (IEMAG), which advises the Irish government on COVID-19 responses. The model assumes a…

We introduce a family of parsimonious network models that are intended to generalize the configuration model to temporal settings. We present consistent estimators for the model parameters and perform numerical simulations to illustrate the…

Methodology · Statistics 2024-07-18 Thien-Minh Le , Hali Hambridge , Jukka-Pekka Onnela

We investigate an epidemic model based on Bailey's continuous differential system. In the continuous time domain, we extend the classical model to time-dependent coefficients and present an alternative solution method to Gleissner's…

Classical Analysis and ODEs · Mathematics 2019-01-01 Martin Bohner , Sabrina Streipert , Delfim F. M. Torres

We study an infection-age structured epidemic model in which both the infectivity and the rate of loss of immunity depend on the time-since-infection. The model can be equivalently viewed as a nonlinear renewal equation for the incidence of…

Dynamical Systems · Mathematics 2025-11-13 Francesca Scarabel , Harry Coldwell , Tyler Cassidy