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Long-distance regulatory interactions between enhancers and their target genes are commonplace in higher eukaryotes. Interposed boundaries or insulators are able to block these long distance regulatory interactions. The mechanistic basis…

Subcellular Processes · Quantitative Biology 2015-05-27 Swagatam Mukhopadhyay , Paul D. Schedl , Vasily M. Studitsky , Anirvan M. Sengupta

Where am I? This is one of the most critical questions that any intelligent system should answer to decide whether it navigates to a previously visited area. This problem has long been acknowledged for its challenging nature in simultaneous…

Robotics · Computer Science 2022-11-10 Konstantinos A. Tsintotas , Loukas Bampis , Antonios Gasteratos

We describe a new generation of algorithms capable of mapping the structure and conformations of macromolecules and their complexes from large ensembles of heterogeneous snapshots, and demonstrate the feasibility of determining both…

Biological Physics · Physics 2014-04-30 P. Schwander , R. Fung , A. Ourmazd

Condensation of hundreds of mega-base-pair-long human chromosomes in a small nuclear volume is a spectacular phenomenon. This process is driven by the formation of chromosome loops. ATP consuming motor, condensin, interacts with chromatin…

Soft Condensed Matter · Physics 2021-10-27 Ryota Takaki , Atreya Dey , Guang Shi , Dave Thirumalai

A recently developed wavelet based approach is employed to characterize the scaling behavior of spectral fluctuations of random matrix ensembles, as well as complex atomic systems. Our study clearly reveals anti-persistent behavior and…

Chaotic Dynamics · Physics 2009-11-11 P. Manimaran , Prasanta K. Panigrahi , P. Anantha Lakshmi

Experimental control and detection of atoms and molecules often rely on optical transitions between different electronic states. In many cases, substructure such as hyperfine or spin-rotation structure leads to the need for multiple optical…

Atomic Physics · Physics 2021-05-26 Connor M. Holland , Yukai Lu , Lawrence W. Cheuk

We present a method based on a time domain simulation of wave propagation that allows studying the optical response of a broad range of dielectric photonic structures. This method is particularly suitable for dealing with complex biological…

Computational Physics · Physics 2013-01-07 Andrés E. Dolinko , Diana C. Skigin

In recent years, the robotics community has extensively examined methods concerning the place recognition task within the scope of simultaneous localization and mapping applications.This article proposes an appearance-based loop closure…

Computer Vision and Pattern Recognition · Computer Science 2022-01-04 Shan An , Haogang Zhu , Dong Wei , Konstantinos A. Tsintotas , Antonios Gasteratos

Persistent homology is a popular computational tool for analyzing the topology of point clouds, such as the presence of loops or voids. However, many real-world datasets with low intrinsic dimensionality reside in an ambient space of much…

Machine Learning · Computer Science 2024-11-01 Sebastian Damrich , Philipp Berens , Dmitry Kobak

Photosynthetic eukaryotes show a remarkable variability in photosynthesis, including large differences in light harvesting proteins and pigment composition. In vivo circular spectropolarimetry enables us to probe the molecular architecture…

Biomolecules · Quantitative Biology 2018-08-27 C. H. Lucas Patty , Freek Ariese , Wybren Jan Buma , Inge Loes ten Kate , Rob J. M. van Spanning , Frans Snik

Recurrence behavior of wave packets in coupled higher dimensional systems and periodically driven systems is analyzed, which takes place in the realm of higher coupling/modulation strength. We analyze the wave packet dynamics close to…

Quantum Physics · Physics 2015-03-17 Muhammad Ayub , Khalid Naseer , Farhan Saif

The article presents the theoretical foundations of the algorithm for calculating the number of different genomes in the medium under study and of two algorithms for determining the presence of a particular (known) genome in this medium.…

Genomics · Quantitative Biology 2015-06-23 Valery Kirzhner , Zeev Volkovich

The analysis of electrical impulse phenomena in cardiac muscle tissue is important for the diagnosis of heart rhythm disorders and other cardiac pathophysiology. Cardiac mapping techniques acquire local temporal measurements and combine…

Medical Physics · Physics 2022-03-21 Jan Lebert , Namita Ravi , Flavio Fenton , Jan Christoph

Multi-photon split states, where each photon is in a different spatial mode, represent an essential resource for various quantum applications, yet their efficient characterization remains an open problem. Here, we formulate the general…

Quantum Physics · Physics 2023-08-30 Jihua Zhang , Andrey A. Sukhorukov

In this research, we consider a mixture of genome fragments of a certain bacteria set. The problem of mixture separation is studied under the assumption that all the genomes present in the mixture are completely sequenced or are close to…

Genomics · Quantitative Biology 2012-03-12 Valery Kirzhner , Zeev Volkovich

Clustering algorithms frequently require the number of clusters to be chosen in advance, but it is usually not clear how to do this. To tackle this challenge when clustering within sequential data, we present a method for estimating the…

Machine Learning · Statistics 2024-07-29 Thomas van Vuren , Thomas Cronk , Jaron Sanders

Owing to technological advances, the number of exoplanets discovered has risen dramatically in the last few years. However, when trying to observe Earth analogs, it is often difficult to test the veracity of detection. We have developed a…

Earth and Planetary Astrophysics · Physics 2017-04-06 Sahil Agarwal , Fabio Del Sordo , John S. Wettlaufer

We show that the possibility to address and image single sites of an optical lattice, now an experimental reality, allows to measure the frequency-resolved local particle and hole spectra of a wide variety of one- and two-dimensional…

Quantum Gases · Physics 2015-10-21 Adrian Kantian , Ulrich Schollwöck , Thierry Giamarchi

Based on cluster de-synchronization properties of phase oscillators, we introduce an efficient method for the detection and identification of modules in complex networks. The performance of the algorithm is tested on computer generated and…

Physics and Society · Physics 2015-06-26 S. Boccaletti , M. Ivanchenko , V. Latora , A. Pluchino , A. Rapisarda

Spectroscopy detected in the time domain entails many techniques, such as FTIR, pump-probe, FT-Raman, and 2DES, and applications, such as molecule characterization, excited state dynamics studies, or spectra classifications. Surprisingly,…

Optics · Physics 2024-05-21 Luca Bolzonello , Niek F van Hulst , Andreas Jakobsson