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In the field of computational pathology, deep learning algorithms have made significant progress in tasks such as nuclei segmentation and classification. However, the potential of these advanced methods is limited by the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2024-07-22 Hyun-Jic Oh , Won-Ki Jeong

Nuclei segmentation and classification is a significant process in pathology image analysis. Deep learning-based approaches have greatly contributed to the higher accuracy of this task. However, those approaches suffer from the imbalanced…

Computer Vision and Pattern Recognition · Computer Science 2023-06-27 Hyun-Jic Oh , Won-Ki Jeong

Automated semantic segmentation of cell nuclei in microscopic images is crucial for disease diagnosis and tissue microenvironment analysis. Nonetheless, this task presents challenges due to the complexity and heterogeneity of cells. While…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhuchen Shao , Sourya Sengupta , Hua Li , Mark A. Anastasio

Nuclei segmentation is a fundamental task in histopathology image analysis. Typically, such segmentation tasks require significant effort to manually generate accurate pixel-wise annotations for fully supervised training. To alleviate such…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Hui Qu , Pengxiang Wu , Qiaoying Huang , Jingru Yi , Zhennan Yan , Kang Li , Gregory M. Riedlinger , Subhajyoti De , Shaoting Zhang , Dimitris N. Metaxas

Neuron segmentation in electron microscopy (EM) aims to reconstruct the complete neuronal connectome; however, current deep learning-based methods are limited by their reliance on large-scale training data and extensive, time-consuming…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Liuyun Jiang , Yanchao Zhang , Jinyue Guo , Yizhuo Lu , Ruining Zhou , Hua Han

Nuclei instance segmentation is an essential task in pathology image analysis, serving as the foundation for many downstream applications. The release of several public datasets has significantly advanced research in this area, yet many…

Image and Video Processing · Electrical Eng. & Systems 2025-08-22 Jiamu Wang , Jin Tae Kwak

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

In multi-class histopathology nuclei analysis tasks, the lack of training data becomes a main bottleneck for the performance of learning-based methods. To tackle this challenge, previous methods have utilized generative models to increase…

Computer Vision and Pattern Recognition · Computer Science 2024-09-05 Seonghui Min , Hyun-Jic Oh , Won-Ki Jeong

Nuclei Segmentation from histology images is a fundamental task in digital pathology analysis. However, deep-learning-based nuclei segmentation methods often suffer from limited annotations. This paper proposes a realistic data augmentation…

Image and Video Processing · Electrical Eng. & Systems 2022-07-01 Yi Lin , Zeyu Wang , Kwang-Ting Cheng , Hao Chen

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Collecting pixel-level labels for medical datasets can be a laborious and expensive process, and enhancing segmentation performance with a scarcity of labeled data is a crucial challenge. This work introduces AugPaint, a data augmentation…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Xinrong Hu , Yiyu Shi

In computer-assisted surgery, automatically recognizing anatomical organs is crucial for understanding the surgical scene and providing intraoperative assistance. While machine learning models can identify such structures, their deployment…

Computer Vision and Pattern Recognition · Computer Science 2024-11-22 Danush Kumar Venkatesh , Dominik Rivoir , Micha Pfeiffer , Fiona Kolbinger , Stefanie Speidel

Deep learning based medical image recognition systems often require a substantial amount of training data with expert annotations, which can be expensive and time-consuming to obtain. Recently, synthetic augmentation techniques have been…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Jiarong Ye , Haomiao Ni , Peng Jin , Sharon X. Huang , Yuan Xue

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Nuclei segmentation is a fundamental task in digital pathology analysis and can be automated by deep learning-based methods. However, the development of such an automated method requires a large amount of data with precisely annotated masks…

Computer Vision and Pattern Recognition · Computer Science 2021-11-25 Jiangbo Shi , Chang Jia , Zeyu Gao , Tieliang Gong , Chunbao Wang , Chen Li

Nuclei segmentation is a crucial task for whole slide image analysis in digital pathology. Generally, the segmentation performance of fully-supervised learning heavily depends on the amount and quality of the annotated data. However, it is…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Yi Lin , Zhiyong Qu , Hao Chen , Zhongke Gao , Yuexiang Li , Lili Xia , Kai Ma , Yefeng Zheng , Kwang-Ting Cheng

In medical image diagnosis, pathology image analysis using semantic segmentation becomes important for efficient screening as a field of digital pathology. The spatial augmentation is ordinary used for semantic segmentation. Tumor images…

Machine Learning · Computer Science 2021-03-04 Takato Yasuno

Image segmentation is an important task in many medical applications. Methods based on convolutional neural networks attain state-of-the-art accuracy; however, they typically rely on supervised training with large labeled datasets. Labeling…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Amy Zhao , Guha Balakrishnan , Frédo Durand , John V. Guttag , Adrian V. Dalca

Large-scale, big-variant, high-quality data are crucial for developing robust and successful deep-learning models for medical applications since they potentially enable better generalization performance and avoid overfitting. However, the…

Computer Vision and Pattern Recognition · Computer Science 2024-12-17 Zheyuan Zhang , Lanhong Yao , Bin Wang , Debesh Jha , Gorkem Durak , Elif Keles , Alpay Medetalibeyoglu , Ulas Bagci

This paper addresses the task of nuclei segmentation in high-resolution histopathological images. We propose an auto- matic end-to-end deep neural network algorithm for segmenta- tion of individual nuclei. A nucleus-boundary model is…

Computer Vision and Pattern Recognition · Computer Science 2020-03-18 Yuxin Cui , Guiying Zhang , Zhonghao Liu , Zheng Xiong , Jianjun Hu
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