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Image synthesis approaches, e.g., generative adversarial networks, have been popular as a form of data augmentation in medical image analysis tasks. It is primarily beneficial to overcome the shortage of publicly accessible data and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Shiyi Du , Xiaosong Wang , Yongyi Lu , Yuyin Zhou , Shaoting Zhang , Alan Yuille , Kang Li , Zongwei Zhou

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

The detection of nuclei is one of the most fundamental components of computational pathology. Current state-of-the-art methods are based on deep learning, with the prerequisite that extensive labeled datasets are available. The increasing…

Image and Video Processing · Electrical Eng. & Systems 2019-07-11 Nicolas Brieu , Armin Meier , Ansh Kapil , Ralf Schoenmeyer , Christos G. Gavriel , Peter D. Caie , Günter Schmidt

Accurate quantification of the extent of lung pathological patterns (fibrosis, ground-glass opacity, emphysema, consolidation) is prerequisite for diagnosis and follow-up of interstitial lung diseases. However, segmentation is challenging…

Image and Video Processing · Electrical Eng. & Systems 2025-01-08 Rezkellah Noureddine Khiati , Pierre-Yves Brillet , Radu Ispas , Catalin Fetita

The development of robust artificial intelligence models for histopathology diagnosis is severely constrained by the scarcity of expert-annotated lesion data, particularly for rare pathologies and underrepresented disease subtypes. While…

Computer Vision and Pattern Recognition · Computer Science 2026-01-14 Mohamad Koohi-Moghadam , Mohammad-Ali Nikouei Mahani , Kyongtae Tyler Bae

In recent years, Denoising Diffusion Models have demonstrated remarkable success in generating semantically valuable pixel-wise representations for image generative modeling. In this study, we propose a novel end-to-end framework, called…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Zhaohu Xing , Liang Wan , Huazhu Fu , Guang Yang , Lei Zhu

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

One of the main challenges in current research on segmentation in cardiac ultrasound is the lack of large and varied labeled datasets and the differences in annotation conventions between datasets. This makes it difficult to design robust…

Image and Video Processing · Electrical Eng. & Systems 2025-02-28 Gilles Van De Vyver , Aksel Try Lenz , Erik Smistad , Sindre Hellum Olaisen , Bjørnar Grenne , Espen Holte , Håavard Dalen , Lasse Løvstakken

Automated cell segmentation in microscopy images is essential for biomedical research, yet conventional methods are labor-intensive and prone to error. While deep learning-based approaches have proven effective, they often require large…

Computer Vision and Pattern Recognition · Computer Science 2024-11-20 Rüveyda Yilmaz , Kaan Keven , Yuli Wu , Johannes Stegmaier

This study introduces Polyp-DDPM, a diffusion-based method for generating realistic images of polyps conditioned on masks, aimed at enhancing the segmentation of gastrointestinal (GI) tract polyps. Our approach addresses the challenges of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Zolnamar Dorjsembe , Hsing-Kuo Pao , Furen Xiao

Precise segmentation and classification of cell instances are vital for analyzing the tissue microenvironment in histology images, supporting medical diagnosis, prognosis, treatment planning, and studies of brain cytoarchitecture. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Valentina Vadori , Jean-Marie Graïc , Antonella Peruffo , Livio Finos , Ujwala Kiran Chaudhari , Enrico Grisan

Despite the increasing use of deep learning in medical image segmentation, the limited availability of annotated training data remains a major challenge due to the time-consuming data acquisition and privacy regulations. In the context of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Pierre Vera , Su Ruan

Image segmentation is crucial in many computational pathology pipelines, including accurate disease diagnosis, subtyping, outcome, and survivability prediction. The common approach for training a segmentation model relies on a pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2025-04-10 Sachin Kumar Danisetty , Alexandros Graikos , Srikar Yellapragada , Dimitris Samaras

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

Nuclei segmentation is a fundamental prerequisite in the digital pathology workflow. The development of automated methods for nuclei segmentation enables quantitative analysis of the wide existence and large variances in nuclei morphometry…

Computer Vision and Pattern Recognition · Computer Science 2024-01-17 Yi Lin , Zeyu Wang , Dong Zhang , Kwang-Ting Cheng , Hao Chen

Image data augmentation constitutes a critical methodology in modern computer vision tasks, since it can facilitate towards enhancing the diversity and quality of training datasets; thereby, improving the performance and robustness of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Panagiotis Alimisis , Ioannis Mademlis , Panagiotis Radoglou-Grammatikis , Panagiotis Sarigiannidis , Georgios Th. Papadopoulos

Denoising diffusion probabilistic models have recently received much research attention since they outperform alternative approaches, such as GANs, and currently provide state-of-the-art generative performance. The superior performance of…

Computer Vision and Pattern Recognition · Computer Science 2022-03-17 Dmitry Baranchuk , Ivan Rubachev , Andrey Voynov , Valentin Khrulkov , Artem Babenko

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim