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In the cancer diagnosis pipeline, digital pathology plays an instrumental role in the identification, staging, and grading of malignant areas on biopsy tissue specimens. High resolution histology images are subject to high variance in…

Image and Video Processing · Electrical Eng. & Systems 2023-08-17 Vasileios Magoulianitis , Catherine A. Alexander , C. -C. Jay Kuo

Automated detection of cervical cancer cells or cell clumps has the potential to significantly reduce error rate and increase productivity in cervical cancer screening. However, most traditional methods rely on the success of accurate cell…

Computer Vision and Pattern Recognition · Computer Science 2019-12-24 Yixiong Liang , Zhihong Tang , Meng Yan , Jialin Chen , Qing Liu , Yao Xiang

The human visual system contains a hierarchical sequence of modules that take part in visual perception at superordinate, basic, and subordinate categorization levels. During the last decades, various computational models have been proposed…

Computer Vision and Pattern Recognition · Computer Science 2021-02-11 Fatemeh Sharifizadeh , Mohammad Ganjtabesh , Abbas Nowzari-Dalini

Automatic detection and segmentation of cells and nuclei in microscopy images is important for many biological applications. Recent successful learning-based approaches include per-pixel cell segmentation with subsequent pixel grouping, or…

Computer Vision and Pattern Recognition · Computer Science 2018-11-09 Uwe Schmidt , Martin Weigert , Coleman Broaddus , Gene Myers

Accurately and quickly binuclear cell (BC) detection plays a significant role in predicting the risk of leukemia and other malignant tumors. However, manual microscopy counting is time-consuming and lacks objectivity. Moreover, with the…

Computer Vision and Pattern Recognition · Computer Science 2022-08-29 Baomin Wang , Geng Hu , Dan Chen , Lihua Hu , Cheng Li , Yu An , Guiping Hu , Guang Jia

Mitosis nuclei count is one of the important indicators for the pathological diagnosis of breast cancer. The manual annotation needs experienced pathologists, which is very time-consuming and inefficient. With the development of deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Huadeng Wang , Zhipeng Liu , Rushi Lan , Zhenbing Liu , Xiaonan Luo , Xipeng Pan , Bingbing Li

Pathology Foundation Models (FMs) have shown strong performance across a wide range of pathology image representation and diagnostic tasks. However, FMs do not exhibit the expected performance advantage over traditional specialized models…

Computer Vision and Pattern Recognition · Computer Science 2026-03-05 Zijiang Yang , Chen Kuang , Dongmei Fu

To address the challenges of table structure recognition, we propose a novel Split-Merge-based top-down model optimized for large, densely populated tables. Our approach formulates row and column splitting as sequence labeling tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Qiyu Hou , Jun Wang

The recent surge in performance for image analysis of digitised pathology slides can largely be attributed to the advances in deep learning. Deep models can be used to initially localise various structures in the tissue and hence facilitate…

Image and Video Processing · Electrical Eng. & Systems 2022-11-15 Simon Graham , Quoc Dang Vu , Mostafa Jahanifar , Shan E Ahmed Raza , Fayyaz Minhas , David Snead , Nasir Rajpoot

Brain tumor segmentation remains a challenge in medical image segmentation tasks. With the application of transformer in various computer vision tasks, transformer blocks show the capability of learning long-distance dependency in global…

Image and Video Processing · Electrical Eng. & Systems 2022-12-07 Liqun Huang , Long Chen , Baihai Zhang , Senchun Chai

Deep learning-based methods are gaining traction in digital pathology, with an increasing number of publications and challenges that aim at easing the work of systematically and exhaustively analyzing tissue slides. These methods often…

Image and Video Processing · Electrical Eng. & Systems 2020-06-25 Ting-An Yen , Hung-Chun Hsu , Pushpak Pati , Maria Gabrani , Antonio Foncubierta-Rodríguez , Pau-Choo Chung

Nuclei segmentation is a fundamental task that is critical for various computational pathology applications including nuclei morphology analysis, cell type classification, and cancer grading. Conventional vision-based methods for nuclei…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Faisal Mahmood , Daniel Borders , Richard Chen , Gregory N. McKay , Kevan J. Salimian , Alexander Baras , Nicholas J. Durr

Nuclear segmentation in histology images is a challenging task due to significant variations in the shape and appearance of nuclei. One of the main hurdles in nuclear instance segmentation is overlapping nuclei where a smart algorithm is…

Image and Video Processing · Electrical Eng. & Systems 2019-08-28 Navid Alemi Koohbanani , Mostafa Jahanifar , Ali Gooya , Nasir Rajpoot

This paper introduces a novel deep-learning method for the automatic detection and segmentation of lung nodules, aimed at advancing the accuracy of early-stage lung cancer diagnosis. The proposed approach leverages a unique "Channel Squeeze…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Mingxiu Sui , Jiacheng Hu , Tong Zhou , Zibo Liu , Likang Wen , Junliang Du

Early detection of lung cancer has been proven to decrease mortality significantly. A recent development in computed tomography (CT), spectral CT, can potentially improve diagnostic accuracy, as it yields more information per scan than…

Computer Vision and Pattern Recognition · Computer Science 2020-07-01 Linde S. Hesse , Pim A. de Jong , Josien P. W. Pluim , Veronika Cheplygina

As Deep Convolutional Neural Networks (DCNNs) have shown robust performance and results in medical image analysis, a number of deep-learning-based tumor detection methods were developed in recent years. Nowadays, the automatic detection of…

Computer Vision and Pattern Recognition · Computer Science 2020-02-12 Zhengdong Zhang , Shuai Li , Ziyang Wang , Yun Lu

Traditional breast cancer image classification methods require manual extraction of features from medical images, which not only require professional medical knowledge, but also have problems such as time-consuming and labor-intensive and…

Image and Video Processing · Electrical Eng. & Systems 2021-04-26 Mengfan Li

Best performing nuclear segmentation methods are based on deep learning algorithms that require a large amount of annotated data. However, collecting annotations for nuclear segmentation is a very labor-intensive and time-consuming task.…

Quantitative Methods · Quantitative Biology 2019-09-10 Mostafa Jahanifar , Navid Alemi Koohbanani , Nasir Rajpoot

As an important research topic in computer vision, fine-grained classification which aims to recognition subordinate-level categories has attracted significant attention. We propose a novel region based ensemble learning network for…

Computer Vision and Pattern Recognition · Computer Science 2019-02-12 Weikuang Li , Tian Wang , Chuanyun Wang , Guangcun Shan , Mengyi Zhang , Hichem Snoussi

Multi-class cell nuclei detection is a fundamental prerequisite in the diagnosis of histopathology. It is critical to efficiently locate and identify cells with diverse morphology and distributions in digital pathological images. Most…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Junjia Huang , Haofeng Li , Xiang Wan , Guanbin Li
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