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A phylogenetic tree is an important way in Bioinformatics to find the evolutionary relationship among biological species. In this research, a proposed model is described for the estimation of a phylogenetic tree for a given set of data. To…

Populations and Evolution · Quantitative Biology 2025-09-03 S M Rafiuddin

Choosing and developing performant database solutions helps organizations optimize their operational practices and decision-making. Since graph data is becoming more common, it is crucial to develop and use them in big data with complex…

Databases · Computer Science 2024-02-01 Johan Sandell , Einar Asplund , Workneh Yilma Ayele , Martin Duneld

Modern data centers that provide Internet-scale services are stadium-size structures housing tens of thousands of heterogeneous devices (server clusters, networking equipment, power and cooling infrastructures) that must operate…

Distributed, Parallel, and Cluster Computing · Computer Science 2014-10-07 Alkida Balliu , Dennis Olivetti , Ozalp Babaoglu , Moreno Marzolla , Alina Sîrbu

Contemporary bioinformatics has seen in profound new visibility into the composition, structure, and history of the natural world around us. Arguably, the central pillar of bioinformatics is phylogenetics -- the study of hereditary…

Populations and Evolution · Quantitative Biology 2024-09-24 Matthew Andres Moreno , Mark T. Holder , Jeet Sukumaran

Recent technological advancements in data acquisition tools allowed life scientists to acquire multimodal data from different biological application domains. Broadly categorized in three types (i.e., sequences, images, and signals), these…

Quantitative Methods · Quantitative Biology 2020-03-03 Mufti Mahmud , M Shamim Kaiser , Amir Hussain

In the rapidly evolving era of Artificial Intelligence (AI), synthetic data are widely used to accelerate innovation while preserving privacy and enabling broader data accessibility. However, the evaluation of synthetic data remains…

PhysiBoSS is an open-source platform that integrates agent-based modeling of cell populations with intracellular stochastic Boolean networks, enabling multiscale simulations of complex biological behaviors. To promote model sharing and…

Quantitative Methods · Quantitative Biology 2025-08-08 Vincent Noel , Marco Ruscone , Randy Heiland , Arnau Montagud , Alfonso Valencia , Emmanuel Barillot , Paul Macklin , Laurence Calzone

Complex logical query answering (CLQA) is a recently emerged task of graph machine learning that goes beyond simple one-hop link prediction and solves a far more complex task of multi-hop logical reasoning over massive, potentially…

Databases · Computer Science 2023-03-28 Hongyu Ren , Mikhail Galkin , Michael Cochez , Zhaocheng Zhu , Jure Leskovec

Large language models (LLMs) have excelled in various natural language processing tasks, but challenges in interpretability and trustworthiness persist, limiting their use in high-stakes fields. Causal discovery offers a promising approach…

Artificial Intelligence · Computer Science 2024-06-10 Wei Zhou , Hong Huang , Guowen Zhang , Ruize Shi , Kehan Yin , Yuanyuan Lin , Bang Liu

Early advancements in convolutional neural networks (CNNs) architectures are primarily driven by human expertise and by elaborate design processes. Recently, neural architecture search was proposed with the aim of automating the network…

Computer Vision and Pattern Recognition · Computer Science 2020-09-16 Zhichao Lu , Ian Whalen , Yashesh Dhebar , Kalyanmoy Deb , Erik Goodman , Wolfgang Banzhaf , Vishnu Naresh Boddeti

This paper introduces PhyloLM, a method adapting phylogenetic algorithms to Large Language Models (LLMs) to explore whether and how they relate to each other and to predict their performance characteristics. Our method calculates a…

Computation and Language · Computer Science 2025-12-09 Nicolas Yax , Pierre-Yves Oudeyer , Stefano Palminteri

Large datasets represented by multidimensional data point clouds often possess non-trivial distributions with branching trajectories and excluded regions, with the recent single-cell transcriptomic studies of developing embryo being notable…

Big data and the Internet of Things era continue to challenge computational systems. Several technology solutions such as NoSQL databases have been developed to deal with this challenge. In order to generate meaningful results from large…

Data Structures and Algorithms · Computer Science 2016-11-11 Vijay Gadepally , Jake Bolewski , Dan Hook , Dylan Hutchison , Ben Miller , Jeremy Kepner

The exponential growth of data in current times and the demand to gain information and knowledge from the data present new challenges for database researchers. Known database systems and algorithms are no longer capable of effectively…

Databases · Computer Science 2017-12-06 Yaron Gonen

Feature transformation aims to reconstruct the feature space of raw features to enhance the performance of downstream models. However, the exponential growth in the combinations of features and operations poses a challenge, making it…

Machine Learning · Computer Science 2024-12-19 Nanxu Gong , Chandan K. Reddy , Wangyang Ying , Haifeng Chen , Yanjie Fu

Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species that evolved from a common ancestor. When phylogenetic trees…

Populations and Evolution · Quantitative Biology 2009-10-19 Leo van Iersel , Steven Kelk , Regula Rupp , Daniel Huson

In this work we present a new application that is being developed. PhyloGrid is able to perform large-scale phylogenetic calculations as those that have been made for estimating the phylogeny of all the sequences already stored in the…

Computational Engineering, Finance, and Science · Computer Science 2015-02-24 Raul Isea , Esther Montes , Antonio J. Rubio-Montero , Rafael Mayo

The rapid growth of AI for Science (AI4S) has underscored the significance of scientific datasets, leading to the establishment of numerous national scientific data centers and sharing platforms. Despite this progress, efficiently promoting…

Information Retrieval · Computer Science 2026-01-06 Qingqing Long , Haotian Chen , Chenyang Zhao , Xiaolei Du , Xuezhi Wang , Pengyao Wang , Chengzan Li , Yuanchun Zhou , Hengshu Zhu

Deep learning (DL) allows computer models to learn, visualize, optimize, refine, and predict data. To understand its present state, examining the most recent advancements and applications of deep learning across various domains is…

Phenomics is an emerging branch of modern biology that uses high throughput phenotyping tools to capture multiple environmental and phenotypic traits, often at massive spatial and temporal scales. The resulting high dimensional data…

Quantitative Methods · Quantitative Biology 2019-06-06 Methun Kamruzzaman , Ananth Kalyanaraman , Bala Krishnamoorthy , Stefan Hey , Patrick Schnable