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With growing exchanges of people and merchandise between countries, epidemics have become an issue of increasing importance and huge amounts of data are being collected every day. Hence, analyses that were usually run in personal computers…

Populations and Evolution · Quantitative Biology 2021-01-19 Bruno Lourenço

Phylogenetic analysis, which allow to understand the evolution of bacterial and viral epidemics, requires large quantities of data to be analysed and processed for knowledge extraction. One of the major challenges consists on the…

Populations and Evolution · Quantitative Biology 2024-05-28 Nyckollas Brandão , André Jesus , André Páscoa , Alexandre P. Francisco , Mário Ramirez , Cátia Vaz

Evolutionary relationships between species are usually inferred through phylogenetic analysis, which provides phylogenetic trees computed from allelic profiles built by sequencing specific regions of the sequences and abstracting them to…

Data Structures and Algorithms · Computer Science 2021-01-01 Luana Silva

PhyloFrame is a Python library for phylogenetic computation targeting the gap between specialist, compiler-optimized operations and flexible, script-based workflows -- with emphasis on fast, memory-efficient operations for very large tree…

Populations and Evolution · Quantitative Biology 2026-05-28 Matthew Andres Moreno , Jeet Sukumaran , Luis Zaman , Emily Dolson

Graph processing has become an important part of multiple areas of computer science, such as machine learning, computational sciences, medical applications, social network analysis, and many others. Numerous graphs such as web or social…

Massive Multi-Omics Microbiome Database (M3DB) is a data warehousing and analytics solution designed to handle diverse, complex, and unprecedented volumes of sequence and taxonomic classification data obtained in a typical microbiome…

Other Quantitative Biology · Quantitative Biology 2015-12-14 Shaun W. Norris , Steven P. Bradley , Hardik I. Parikh , Nihar U. Sheth

We present fVDB, a novel GPU-optimized framework for deep learning on large-scale 3D data. fVDB provides a complete set of differentiable primitives to build deep learning architectures for common tasks in 3D learning such as convolution,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Francis Williams , Jiahui Huang , Jonathan Swartz , Gergely Klár , Vijay Thakkar , Matthew Cong , Xuanchi Ren , Ruilong Li , Clement Fuji-Tsang , Sanja Fidler , Eftychios Sifakis , Ken Museth

The increasing risk of epidemics and a fast-growing world population has contributed to a great investment in phylogenetic analysis, in order to track numerous diseases and conceive effective medication and treatments. Phylogenetic analysis…

Social and Information Networks · Computer Science 2022-11-29 Miguel Luis , Catia Vaz

One of the purposes of Big Data systems is to support analysis of data gathered from heterogeneous data sources. Since data warehouses have been used for several decades to achieve the same goal, they could be leveraged also to provide…

Databases · Computer Science 2018-09-13 Darja Solodovnikova , Laila Niedrite

As data-driven methods are becoming pervasive in a wide variety of disciplines, there is an urgent need to develop scalable and sustainable tools to simplify the process of data science, to make it easier to keep track of the analyses being…

Databases · Computer Science 2016-10-18 Hui Miao , Amit Chavan , Amol Deshpande

Multimodal medical information processing is currently the epicenter of intense interdisciplinary research, as proper data fusion may lead to more accurate diagnoses. Moreover, multimodality may disambiguate cases of co-morbidity. This…

Information Retrieval · Computer Science 2017-02-23 Georgios Drakopoulos , Vasileios Megalooikonomou

Phylogenetics is a branch of computational biology that studies the evolutionary relationships among biological entities. Its long history and numerous applications notwithstanding, inference of phylogenetic trees from sequence data remains…

Populations and Evolution · Quantitative Biology 2024-03-26 Mingyang Zhou , Zichao Yan , Elliot Layne , Nikolay Malkin , Dinghuai Zhang , Moksh Jain , Mathieu Blanchette , Yoshua Bengio

Phylogenetics is the study of the evolutionary relationships between organisms. One of the main challenges in the field is to take biological data for a group of organisms and to infer an evolutionary tree, a graph that represents these…

Populations and Evolution · Quantitative Biology 2019-06-05 Elizabeth Gross , Colby Long , Joseph Rusinko

PathDB is a Java-based graph database designed for in-memory data loading and querying. By utilizing Regular Path Queries (RPQ) and a closed path algebra, PathDB processes paths through its three main components: the parser, the logical…

Databases · Computer Science 2025-07-04 Roberto García , Renzo Angles , Vicente Rojas , Sebastián Ferrada

Phylogenetic profiles - presence-absence patterns of genes across taxa - are rich information sources for inferring the evolutionary history of genes and gene families. When aggregated across many genes, these profiles can reveal…

Populations and Evolution · Quantitative Biology 2025-07-10 Vinh Tran , Ingo Ebersberger

Phylogenetics is a fundamental component of evolutionary analysis frameworks in biology and linguistics. Recently, the advent of large-scale genomics and the SARS-CoV-2 pandemic has highlighted the necessity for phylogenetic software to…

Graph databases have grown in popularity in recent years as they are able to efficiently store and query complex relationships between data. Incidentally, navigation data and road networks can be processed, sampled or modified efficiently…

Databases · Computer Science 2023-06-13 Karin Festl , Patrick Promitzer , Daniel Watzenig , Huilin Yin

This tutorial serves as a comprehensive guide for understanding graph databases, focusing on the fundamentals of graph theory while showcasing practical applications across various fields. It starts by introducing foundational concepts and…

Databases · Computer Science 2024-11-18 Sydney Anuyah , Victor Bolade , Oluwatosin Agbaakin

In recent years, neural networks have shown impressive performance gains on long-standing AI problems, and in particular, answering queries from natural language text. These advances raise the question of whether they can be extended to a…

Computation and Language · Computer Science 2020-10-15 James Thorne , Majid Yazdani , Marzieh Saeidi , Fabrizio Silvestri , Sebastian Riedel , Alon Halevy

OLAF (Open Life Science Analysis Framework) is an open-source platform that enables researchers to perform bioinformatics analyses using natural language. By combining large language models (LLMs) with a modular agent-pipe-router…

Quantitative Methods · Quantitative Biology 2025-04-14 Dylan Riffle , Nima Shirooni , Cody He , Manush Murali , Sovit Nayak , Rishikumar Gopalan , Diego Gonzalez Lopez
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