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In the last decades, unsupervised deep learning based methods have caught researchers attention, since in many real applications, such as medical imaging, collecting a great amount of training examples is not always feasible. Moreover, the…

Image and Video Processing · Electrical Eng. & Systems 2022-05-24 Pasquale Cascarano , Andrea Sebastiani , Maria Colomba Comes , Giorgia Franchini , Federica Porta

Fontan-Associated Liver Disease (FALD) is a disorder arising from hemodynamic changes and venous congestion in the liver. This disease is prominent in patients with hypoplastic left heart syndrome (HLHS). Although HLHS patients typically…

Medical Physics · Physics 2025-11-06 Yaqi Li , Justin D. Weigand , Charles Puelz , Mette S. Olufsen , Alyssa Taylor-LaPole

We present validation of benchmark experimental data for computational fluid dynamics (CFD) analyses of medical devices using advanced Particle Image Velocimetry (PIV) processing and post-processing techniques. This work is an extension of…

Reconstructing cardiac electrical activity from body surface electric potential measurements results in the severely ill-posed inverse problem in electrocardiography. Many different regularization approaches have been proposed to improve…

Numerical Analysis · Mathematics 2025-11-04 Manuel Haas , Thomas Grandits , Thomas Pinetz , Thomas Beiert , Simone Pezzuto , Alexander Effland

We propose a variational regularization approach based on a multiscale representation called cylindrical shearlets aimed at dynamic imaging problems, especially dynamic tomography. The intuitive idea of our approach is to integrate a…

Numerical Analysis · Mathematics 2025-08-05 Tatiana A. Bubba , Tommi Heikkilä , Demetrio Labate , Luca Ratti

Objective: To develop an automatic image normalization algorithm for intensity correction of images from breast dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) acquired by different MRI scanners with various imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-07-09 Jun Zhang , Ashirbani Saha , Brian J. Soher , Maciej A. Mazurowski

MRI-linear accelerator (MRI-Linac) systems allow for daily tracking of MRI changes during radiotherapy (RT). Since one common MRI-Linac operates at 0.35T, there are efforts towards developing protocols at that field strength. In this study…

We examine two models for hepatitis C viral (HCV) dynamics, one for monotherapy with interferon (IFN) and the other for combination therapy with IFN and ribavirin. Optimal therapy for both the models is determined using the steepest…

Quantitative Methods · Quantitative Biology 2011-09-06 Gaurav Pachpute , Siddhartha P. Chakrabarty

We propose to learn non-convex regularizers with a prescribed upper bound on their weak-convexity modulus. Such regularizers give rise to variational denoisers that minimize a convex energy. They rely on few parameters (less than 15,000)…

Image and Video Processing · Electrical Eng. & Systems 2023-12-21 Alexis Goujon , Sebastian Neumayer , Michael Unser

In this paper, we propose a novel channel estimation scheme for pulse-shaped multicarrier systems using smoothness regularization for ultra-reliable low-latency communication (URLLC). It can be applied to any multicarrier system with or…

Information Theory · Computer Science 2024-10-28 Andreas Pfadler , Tom Szollmann , Peter Jung , Slawomir Stanczak

The development of computed tomography (CT) image reconstruction methods that significantly reduce patient radiation exposure while maintaining high image quality is an important area of research in low-dose CT (LDCT) imaging. We propose a…

Machine Learning · Statistics 2019-06-14 Xuehang Zheng , Saiprasad Ravishankar , Yong Long , Jeffrey A. Fessler

The purpose of this study is to develop a computer-aided diagnosis system for classifying benign and malignant lung lesions, and to assist physicians in real-time analysis of radial probe endobronchial ultrasound (EBUS) videos. During the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-09 Ching-Kai Lin , Chin-Wen Chen , Yun-Chien Cheng

Purpose: A combined diffusion-relaxometry MR acquisition and analysis pipeline for in-vivo human placenta, which allows for exploration of coupling between T2* and apparent diffusion coefficient (ADC) measurements in a sub 10 minute scan…

The automated analysis of medical time series, such as the electrocardiogram (ECG), electroencephalogram (EEG), pulse oximetry, etc, has the potential to serve as a valuable tool for diagnostic decisions, allowing for remote monitoring of…

We propose a regularization-based image restoration scheme for 2D images recorded over time (2D+t). We design an infimal convolution-based regularization function which we call spatio-temporal Adaptive Infimal Convolution (STAIC)…

Image and Video Processing · Electrical Eng. & Systems 2024-04-09 Deepak G Skariah , Muthuvel Arigovindan

There has been an increasing focus in learning interpretable feature representations, particularly in applications such as medical image analysis that require explainability, whilst relying less on annotated data (since annotations can be…

Computer Vision and Pattern Recognition · Computer Science 2019-11-19 Gabriele Valvano , Agisilaos Chartsias , Andrea Leo , Sotirios A. Tsaftaris

Recent advances align diffusion models with human preferences to increase aesthetic appeal and mitigate artifacts and biases. Such methods aim to maximize a conditional output distribution aligned with higher rewards whilst not drifting far…

Machine Learning · Computer Science 2026-02-23 Ratnavibusena Don Shahain Manujith , Teoh Tze Tzun , Kenji Kawaguchi , Yang Zhang

PET imaging is widely employed for observing biological metabolic activities within the human body. However, numerous benign conditions can cause increased uptake of radiopharmaceuticals, confounding differentiation from malignant tumors.…

Image and Video Processing · Electrical Eng. & Systems 2024-10-31 Ran Hong , Yuxia Huang , Lei Liu , Zhonghui Wu , Bingxuan Li , Xuemei Wang , Qiegen Liu

Single-Photon Emission Computed Tomography (SPECT) is widely applied for the diagnosis of coronary artery diseases. Low-dose (LD) SPECT aims to minimize radiation exposure but leads to increased image noise. Limited-view (LV) SPECT, such as…

Image and Video Processing · Electrical Eng. & Systems 2024-01-25 Xiongchao Chen , Bo Zhou , Xueqi Guo , Huidong Xie , Qiong Liu , James S. Duncan , Albert J. Sinusas , Chi Liu

Discriminatively learned correlation filters (DCF) have been widely used in online visual tracking filed due to its simplicity and efficiency. These methods utilize a periodic assumption of the training samples to construct a circulant data…

Computer Vision and Pattern Recognition · Computer Science 2017-06-02 Xiaoxiang Hu , Yujiu Yang