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Medical image analysis relies on accurate segmentation, and benefits from controllable synthesis (of new training images). Yet both tasks of the cyclical pipeline face spatial imbalance: lesions occupy small regions against vast…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Anugunj Naman , Ayushman Singh , Gaibo Zhang , Yaguang Zhang

Ultrasound (US) is a critical modality for diagnosing liver fibrosis. Unfortunately, assessment is very subjective, motivating automated approaches. We introduce a principled deep convolutional neural network (CNN) workflow that…

Image and Video Processing · Electrical Eng. & Systems 2020-08-11 Bowen Li , Ke Yan , Dar-In Tai , Yuankai Huo , Le Lu , Jing Xiao , Adam P. Harrison

Purpose: To introduce a novel deep learning based approach for fast and high-quality dynamic multi-coil MR reconstruction by learning a complementary time-frequency domain network that exploits spatio-temporal correlations simultaneously…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Chen Qin , Jinming Duan , Kerstin Hammernik , Jo Schlemper , Thomas Küstner , René Botnar , Claudia Prieto , Anthony N. Price , Joseph V. Hajnal , Daniel Rueckert

Model-based reconstruction employing the time separation technique (TST) was found to improve dynamic perfusion imaging of the liver using C-arm cone-beam computed tomography (CBCT). To apply TST using prior knowledge extracted from CT…

The local number variance associated with a spherical sampling window of radius $R$ enables a classification of many-particle systems in $d$-dimensional Euclidean space according to the degree to which large-scale density fluctuations are…

Statistical Mechanics · Physics 2021-05-12 Salvatore Torquato , Jaeuk Kim , Michael A. Klatt

A common approach to medical image analysis on volumetric data uses deep 2D convolutional neural networks (CNNs). This is largely attributed to the challenges imposed by the nature of the 3D data: variable volume size, GPU exhaustion during…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Hasib Zunair , Aimon Rahman , Nabeel Mohammed , Joseph Paul Cohen

Purpose: The main purpose of this study was to assess the reliability of shape and heterogeneity features in both Positron Emission Tomography (PET) and low-dose Computed Tomography (CT) components of PET/CT. A secondary objective was to…

Computer Vision and Pattern Recognition · Computer Science 2016-10-06 Marie-Charlotte Desseroit , Florent Tixier , Wolfgang Weber , Barry A Siegel , Catherine Cheze Le Rest , Dimitris Visvikis , Mathieu Hatt

Objective: Dynamic cone-beam CT (CBCT) imaging is highly desired in image-guided radiation therapy to provide volumetric images with high spatial and temporal resolutions to enable applications including tumor motion tracking/prediction and…

Medical Physics · Physics 2023-02-22 You Zhang , Tielige Mengke

Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…

Image and Video Processing · Electrical Eng. & Systems 2025-07-16 Duoyou Chen , Yunqing Chen , Can Zhang , Zhou Wang , Cheng Chen , Ruoxiu Xiao

Effective clutter filtering is crucial in suppressing tissue clutter and extracting blood flow signal in Doppler ultrasound. Recent advances in eigen-based clutter filtering techniques have enabled ultrasound imaging of microvasculature…

Medical Physics · Physics 2024-05-21 Chengwu Huang , U-Wai Lok , Jingke Zhang , Hui Liu , Shigao Chen

Interpretability is essential in medical imaging to ensure that clinicians can comprehend and trust artificial intelligence models. In this paper, we propose a novel interpretable approach that combines attribute regularization of the…

Image and Video Processing · Electrical Eng. & Systems 2023-12-15 Maxime Di Folco , Cosmin I. Bercea , Julia A. Schnabel

Most existing trackers based on discriminative correlation filters (DCF) try to introduce predefined regularization term to improve the learning of target objects, e.g., by suppressing background learning or by restricting change rate of…

Computer Vision and Pattern Recognition · Computer Science 2020-03-31 Yiming Li , Changhong Fu , Fangqiang Ding , Ziyuan Huang , Geng Lu

Low-dose computed tomography (LDCT) offers significant advantages in reducing the potential harm to human bodies. However, reducing the X-ray dose in CT scanning often leads to severe noise and artifacts in the reconstructed images, which…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Ran An , Yinghui Zhang , Xi Chen , Lemeng Li , Ke Chen , Hongwei Li

Image registration is useful for quantifying morphological changes in longitudinal MR images from prostate cancer patients. This paper describes a development in improving the learning-based registration algorithms, for this challenging…

Image and Video Processing · Electrical Eng. & Systems 2022-07-15 Ziyi Shen , Qianye Yang , Yuming Shen , Francesco Giganti , Vasilis Stavrinides , Richard Fan , Caroline Moore , Mirabela Rusu , Geoffrey Sonn , Philip Torr , Dean Barratt , Yipeng Hu

Purpose: To apply tracer kinetic models as temporal constraints during reconstruction of under-sampled dynamic contrast enhanced (DCE) MRI. Methods: A library of concentration v.s time profiles is simulated for a range of physiological…

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is essential for breast cancer diagnosis due to its ability to characterize tissue through contrast agent kinetics. However, traditional DCE-MRI protocols require multiple…

Computer Vision and Pattern Recognition · Computer Science 2025-01-28 Ruben D. Fonnegra , Maria Liliana Hernández , Juan C. Caicedo , Gloria M. Díaz

Over the past few decades, researchers have developed several approaches such as the Reference Phantom Method (RPM) to estimate ultrasound attenuation coefficient (AC) and backscatter coefficient (BSC). AC and BSC can help to discriminate…

Medical Physics · Physics 2017-12-12 Kajoli Banerjee Krishnan , Nithin Nagaraj , Nitin Singhal , Shalini Thapar , Komal Yadav

Perfusion imaging is a valuable tool for diagnosing and treatment planning for liver tumours. The time separation technique (TST) has been successfully used for modelling C-arm cone-beam computed tomography (CBCT) perfusion data. The…

Continuous-time generative models, such as diffusion models, flow matching, and rectified flow, learn time-dependent vector fields but are typically trained with objectives that treat timesteps independently, leading to high estimator…

Machine Learning · Computer Science 2026-02-23 Chika Maduabuchi , Jindong Wang

Purpose: This study quantifies the variation in dose-volume histogram (DVH) and normal tissue complication probability (NTCP) metrics for head-and-neck (HN) cancer patients when alternative organ-at-risk (OAR) delineations are used for…