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In recent years, the availability of digitized Whole Slide Images (WSIs) has enabled the use of deep learning-based computer vision techniques for automated disease diagnosis. However, WSIs present unique computational and algorithmic…

Image and Video Processing · Electrical Eng. & Systems 2021-06-15 Yash Sharma , Aman Shrivastava , Lubaina Ehsan , Christopher A. Moskaluk , Sana Syed , Donald E. Brown

This paper focuses on webly supervised learning (WSL), where datasets are built by crawling samples from the Internet and directly using search queries as web labels. Although WSL benefits from fast and low-cost data collection, noises in…

Computer Vision and Pattern Recognition · Computer Science 2020-08-28 Jingkang Yang , Litong Feng , Weirong Chen , Xiaopeng Yan , Huabin Zheng , Ping Luo , Wayne Zhang

Self-supervised learning (SSL) is able to build latent representations that generalize well to unseen data. However, only a few SSL techniques exist for the online CL setting, where data arrives in small minibatches, the model must comply…

Machine Learning · Computer Science 2025-07-16 Giacomo Cignoni , Andrea Cossu , Alexandra Gomez-Villa , Joost van de Weijer , Antonio Carta

The histopathological analysis of whole-slide images (WSIs) is fundamental to cancer diagnosis but is a time-consuming and expert-driven process. While deep learning methods show promising results, dominant patch-based methods artificially…

Image and Video Processing · Electrical Eng. & Systems 2025-10-08 Alexander Weers , Alexander H. Berger , Laurin Lux , Peter Schüffler , Daniel Rueckert , Johannes C. Paetzold

Medical image classification is a challenging task due to the scarcity of labeled samples and class imbalance caused by the high variance in disease prevalence. Semi-supervised learning (SSL) methods can mitigate these challenges by…

Computer Vision and Pattern Recognition · Computer Science 2023-07-11 Md Junaid Mahmood , Pranaw Raj , Divyansh Agarwal , Suruchi Kumari , Pravendra Singh

Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zahra Rahimi Afzal , Wataru Uegami , Saghir Alfasly , Saba Yasir , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Automatic histopathology image segmentation is crucial to disease analysis. Limited available labeled data hinders the generalizability of trained models under the fully supervised setting. Semi-supervised learning (SSL) based on generative…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Hongxiao Wang , Hao Zheng , Jianxu Chen , Lin Yang , Yizhe Zhang , Danny Z. Chen

Self-supervised learning (SSL) has recently achieved promising performance for 3D medical image analysis tasks. Most current methods follow existing SSL paradigm originally designed for photographic or natural images, which cannot…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Yankai Jiang , Mingze Sun , Heng Guo , Xiaoyu Bai , Ke Yan , Le Lu , Minfeng Xu

Self-supervised learning (SSL) has become the de facto training paradigm of large models, where pre-training is followed by supervised fine-tuning using domain-specific data and labels. Despite demonstrating comparable performance with…

Machine Learning · Computer Science 2024-06-05 Sofia Yfantidou , Dimitris Spathis , Marios Constantinides , Athena Vakali , Daniele Quercia , Fahim Kawsar

Local representation learning has been a key challenge to promote the performance of the histopathological whole slide images analysis. The previous representation learning methods followed the supervised learning paradigm. However, manual…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Jun Li , Yushan Zheng , Kun Wu , Jun Shi , Fengying Xie , Zhiguo Jiang

Self-supervised learning (SSL) has led to important breakthroughs in computer vision by allowing learning from large amounts of unlabeled data. As such, it might have a pivotal role to play in biomedicine where annotating data requires a…

Computer Vision and Pattern Recognition · Computer Science 2024-03-14 Roy Hirsch , Mathilde Caron , Regev Cohen , Amir Livne , Ron Shapiro , Tomer Golany , Roman Goldenberg , Daniel Freedman , Ehud Rivlin

Detectingandsegmentingobjectswithinwholeslideimagesis essential in computational pathology workflow. Self-supervised learning (SSL) is appealing to such annotation-heavy tasks. Despite the extensive benchmarks in natural images for dense…

Computer Vision and Pattern Recognition · Computer Science 2022-07-15 Jiawei Yang , Hanbo Chen , Yuan Liang , Junzhou Huang , Lei He , Jianhua Yao

Self-supervised learning (SSL) has rapidly emerged as a transformative approach in computer vision, enabling the extraction of rich feature representations from vast amounts of unlabeled data and reducing reliance on costly manual…

Computer Vision and Pattern Recognition · Computer Science 2025-05-19 Nikolaos Giakoumoglou , Tania Stathaki , Athanasios Gkelias

This paper presents an autoencoder-based neural network architecture to compress histopathological images while retaining the denser and more meaningful representation of the original images. Current research into improving compression…

Image and Video Processing · Electrical Eng. & Systems 2023-05-15 Agnes Barsi , Suvendu Chandan Nayak , Sasmita Parida , Raj Mani Shukla

Self-Supervised Learning (SSL) is an increasingly popular ML paradigm that trains models to transform complex inputs into representations without relying on explicit labels. These representations encode similarity structures that enable…

Machine Learning · Computer Science 2022-06-30 Adam Dziedzic , Nikita Dhawan , Muhammad Ahmad Kaleem , Jonas Guan , Nicolas Papernot

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

Computer-aided diagnosis via deep learning relies on large-scale annotated data sets, which can be costly when involving expert knowledge. Semi-supervised learning (SSL) mitigates this challenge by leveraging unlabeled data. One effective…

Machine Learning · Computer Science 2020-05-25 Prashnna Kumar Gyawali , Sandesh Ghimire , Pradeep Bajracharya , Zhiyuan Li , Linwei Wang

Training a neural network with a large labeled dataset is still a dominant paradigm in computational histopathology. However, obtaining such exhaustive manual annotations is often expensive, laborious, and prone to inter and Intra-observer…

Computer Vision and Pattern Recognition · Computer Science 2021-11-03 Chetan L. Srinidhi , Seung Wook Kim , Fu-Der Chen , Anne L. Martel

Advances in optical microscopy scanning have significantly contributed to computational pathology (CPath) by converting traditional histopathological slides into whole slide images (WSIs). This development enables comprehensive digital…

Image and Video Processing · Electrical Eng. & Systems 2024-11-19 Xitong Ling , Yuanyuan Lei , Jiawen Li , Junru Cheng , Wenting Huang , Tian Guan , Jian Guan , Yonghong He

We approach self-supervised learning of image representations from a statistical dependence perspective, proposing Self-Supervised Learning with the Hilbert-Schmidt Independence Criterion (SSL-HSIC). SSL-HSIC maximizes dependence between…

Machine Learning · Statistics 2021-12-06 Yazhe Li , Roman Pogodin , Danica J. Sutherland , Arthur Gretton
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