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Biological systems are known to be highly transparent to 700-1100nm near-infrared (NIR) light. It is shown here that the strong optical absorbance of single-walled carbon nanotubes (SWNTs) in this special spectral window, an intrinsic…

Materials Science · Physics 2015-06-25 Nadine Wong Shi Kam , Michael O'Connell , Jeffrey A. Wisdom , Hongjie Dai

Background: Targeted radiotherapies with low-energy ions show interesting possibilities for the selective irradiation of tumor cells, a strategy particularly appropriate for the treatment of disseminated cancer. Two promising examples are…

Medical Physics · Physics 2024-09-23 Mario Alcocer-Ávila , Victor Levrague , Rachel Delorme , Étienne Testa , Michaël Beuve

The penetration of dendrites in ceramic lithium conductors severely constrains the development of solid-state batteries (SSBs) while its nanoscopic origin remain unelucidated. We develop an in-situ nanoscale electrochemical characterization…

Compact, high-performance components in millimeter-wave (mmWave) communication systems demand new acoustic filter technology at increasingly higher frequencies. Among various promising mmWave platforms, first-order antisymmetric (A1) mode…

Carbon nanotubes exhibit many unique intrinsic physical and chemical properties and have been intensively explored for biological and biomedical applications. In this review, we summarize the main results of our and other groups in this…

Materials Science · Physics 2009-02-10 Zhuang Liu , Scott Tabakman , Kevin Welsher , Hongjie Dai

The poor delivery of nanoparticles to target cancer cells hinders their success in the clinical setting. In this work, an alternative target readily available for circulating nanoparticles has been selected to eliminate the need for…

Biological Physics · Physics 2021-03-18 Juan L. Paris , Gonzalo Villaverde , Sergio Gomez-Grana , Maria Vallet-Regi

Major obstacles to the successful treatment of gliolastoma multiforme are mostly related to the acquired resistance to chemotherapy drugs and, after surgery, to the cancer recurrence in correspondence of residual microscopic foci. As…

Short single-walled carbon nanotubes (SWNTs) functionalized by PEGylated phospholipids are biologically non-toxic and long-circulating nanomaterials with intrinsic near infrared photoluminescence (NIR PL), characteristic Raman spectra, and…

The prompt identification of pancreatic cancer symptoms is an ongoing clinical challenge, often leading to late diagnosis and poor prognosis. Tumor 'hijacking' of the pancreatic stromal structure limits the uptake of systemic…

Intermetallic Nb3Sn alloys have long been believed to form through Sn diffusion into Nb. However, our observations of significant oxygen content in Nb3Sn prompted an investigation of alternative formation mechanisms. Through experiments…

Biomedical applications of carbon nanotubes have attracted much attention in recent years. Here, we summarize our previously developed protocols for functionalization and bioconjugation of single wall carbon nanotubes (SWNTs) for various…

Materials Science · Physics 2009-10-06 Zhuang Liu , Scott Tabakman , Zhuo Chen , Hongjie Dai

Multifunctional nanomaterials combining diagnosis and therapeutic properties have attracted a considerable attention in cancer research. Yet some important challenges are still to be faced, including an optimal coupling between these two…

Biological Physics · Physics 2019-10-31 Yupeng Shi , Flavien Guenneau , Xiaolin Wang , Christophe Hélary , Thibaud Coradin

We report on scalable heterointegration of superconducting electrodes and epitaxial semiconductor quantum dots on strong piezoelectric and optically nonlinear lithium niobate. The implemented processes combine the sputter-deposited thin…

Nanocomposite material ($\mathrm{GGAG:Ce^{3+}@SiO_2-RB}$) for potential use in X-ray induced photodynamic therapy (X-PDT) was developed, thoroughly characterized, and evaluated. It consists of a scintillating…

The in vivo propulsion and monitoring of nanoparticles (NPs) have received tremendous achievements in the past decade. Developing functional NPs that can be efficiently manipulated inside the human body with a non-invasive tracking modality…

Biological Physics · Physics 2024-10-07 Jiayan Li , Chang Xu , Yingna Chen , Junmei Cao , Wanli Ye , Yu Cheng , Qian Cheng

Stereotactic body radiation therapy (SBRT) refers to focusing high-energy rays in three-dimensional space on the tumor lesion area, reducing the dose received by surrounding normal tissues, which can effectively improve the local control…

Medical Physics · Physics 2024-02-27 Yanqi Zong , Zhengrong Cui , Luqi Lin , Sihao Wang , Yizhi Chen

Theranostics, the combination of diagnosis and therapy, has long held promise as a means to achieving personalised precision cancer treatments. However, despite its potential, theranostics has yet to realise significant clinical…

Chemically functionalized single-walled carbon nanotubes (SWNTs) have shown promise in tumor targeted accumulation in mice and exhibit biocompatibility, excretion and little toxicity. Here, we demonstrate in-vivo SWNT drug delivery for…

Materials Science · Physics 2008-08-26 Zhuang Liu , Kai Chen , Corrine Davis , Sarah Sherlock , Qizhen Cao , Xiaoyuan Chen , Hongjie Dai

Photodynamic therapy (PDT) is a targeted cancer treatment that uses light-activated photosensitizers to generate reactive oxygen species that selectively destroy tumor cells, generally causing less collateral damage than conventional…

Approximately 90% of cancers have their origins in epithelial tissues and this leads to epithelial thickening, but the ultrastructural changes and underlying architecture is less well known. Depth resolved label free visualization of…

Medical Physics · Physics 2020-05-28 Nandan Das , Alexandrov Sergey , Yi Zhou , Katie E. Gilligan , Róisín M Dwyer , Martin Leahy
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