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A rapid decline in mortality and fertility has become major issues in many developed countries over the past few decades. A precise model for forecasting demographic movements is important for decision making in social welfare policies and…

Machine Learning · Statistics 2024-12-30 Ka Kin Lam , Bo Wang

The United Nations' Sustainable Development Goal 3.2 aims to reduce under-5 child mortality to 25 deaths per 1,000 live births by 2030. Child mortality tends to be concentrated in developing regions where much of the information needed to…

Applications · Statistics 2018-10-10 Katie Wilson , Jon Wakefield

Conventional survival analysis approaches estimate risk scores or individualized time-to-event distributions conditioned on covariates. In practice, there is often great population-level phenotypic heterogeneity, resulting from (unknown)…

Machine Learning · Statistics 2020-03-03 Paidamoyo Chapfuwa , Chunyuan Li , Nikhil Mehta , Lawrence Carin , Ricardo Henao

Cure models have been developed as an alternative modelling approach to conventional survival analysis in order to account for the presence of cured subjects that will never experience the event of interest. Mixture cure models, which model…

Methodology · Statistics 2022-07-19 Eni Musta , Valentin Patilea , Ingrid Van Keilegom

Accurate cancer risk estimation is crucial to clinical decision-making, such as identifying high-risk people for screening. However, most existing cancer risk models incorporate data from epidemiologic studies, which usually cannot…

Methodology · Statistics 2023-10-26 Lingxiao Wang , Yan Li , Barry Graubard , Hormuzd Katki

Objective: To exploit state variations in infant mortality, identify diagnoses that contributed to reduction of the infant mortality rate (IMR), and examine factors associated with preterm related mortality rate (PMR). Methods: Using linked…

Applications · Statistics 2020-12-22 Alireza Ebrahimvandi , Niyousha Hosseinichimeh , Jay Iams

This research analyses the axiomatic link among health expenditures, inflation rate, and gross national income (GNI) per capita concerning the child mortality (CMU5) rate in D-8 nations, employing panel data analysis from 1995 to 2014.…

Theoretical Economics · Economics 2026-01-06 M. Waseem Akram , Binita Shahi , M. Javed Akram

The estimation of unknown parameters in simulations, also known as calibration, is crucial for practical management of epidemics and prediction of pandemic risk. A simple yet widely used approach is to estimate the parameters by minimizing…

Methodology · Statistics 2023-06-26 Chih-Li Sung , Ying Hung

When considering many survival models, decisions become more challenging in health economic evaluation. In this paper, we present a set of methods to assist with selecting the most appropriate parametric survival models. The methods…

Methodology · Statistics 2025-10-22 Ben Lee

In low and middle income countries, household surveys are a valuable source of information for a range of health and demographic indicators. Increasingly, subnational estimates are required for targeting interventions and evaluating…

Methodology · Statistics 2020-09-21 Katie Wilson , Jon Wakefield

Existing mortality forecasting methods focus on age-specific mortality rates, which lie in an unconstrained space and overlook the distributional nature of life-table death counts. Few studies have developed and compared forecasting methods…

Methodology · Statistics 2026-04-23 Han Lin Shang , Cristian F. Jiménez-Varón

Age-disaggregated health data is crucial for effective public health planning and monitoring. Monitoring under-five mortality, for example, requires highly detailed age data since the distribution of potential causes of death varies…

Applications · Statistics 2023-02-23 Shuxian Fan , Li Liu , Jamie Perin , Tyler H. McCormick

The current outbreak of COVID-19 has called renewed attention to the need for sound statistical analysis for monitoring mortality patterns and trends over time. Excess mortality has been suggested as the most appropriate indicator to…

Applications · Statistics 2020-10-13 Patrizio Vanella , Ugofilippo Basellini , Berit Lange

Age-specific mortality improvements are non-uniform, neither across ages nor across time. We propose a two-step procedure to estimate the rates of mortality improvement (RMI) in age-specific death rates (ASDR) at ages 85 and above for ten…

Applications · Statistics 2023-03-30 Trifon I. Missov , Silvio C. Patricio , Francisco Villavicencio

Undernutrition, resulting in restricted growth, and quantified here using height-for-age z-scores, is an important contributor to childhood morbidity and mortality. Since all levels of mild, moderate and severe undernutrition are of…

Applications · Statistics 2015-12-08 Mariel M. Finucane , Christopher J. Paciorek , Gretchen A. Stevens , Majid Ezzati

Survival analysis is a statistical technique used to estimate the time until an event occurs. Although it is applied across a wide range of fields, adjusting for reporting delays under practical constraints remains a significant challenge…

Machine Learning · Statistics 2025-10-27 Yuta Shikuri , Hironori Fujisawa

BACKGROUND. The majority of countries in Africa and nearly one third of all countries require mortality models to infer complete age schedules of mortality, required for population estimates, projections/forecasts and many other tasks in…

Applications · Statistics 2016-12-06 Samuel J. Clark

Chronic diseases are long-lasting conditions that require lifelong medical attention. Using big EMR data, we have developed early disease risk prediction models for five common chronic diseases: diabetes, hypertension, CKD, COPD, and…

Machine Learning · Computer Science 2026-03-13 Shaheer Ahmad Khan , Muhammad Usamah Shahid , Muddassar Farooq

Understanding patterns in mortality across subpopulations is essential for local health policy decision making. One of the key challenges of subnational mortality rate estimation is the presence of small populations and zero or near zero…

Applications · Statistics 2025-12-16 Ameer Dharamshi , Monica Alexander , Celeste Winant , Magali Barbieri

Parameter shrinkage applied optimally can always reduce error and projection variances from those of maximum likelihood estimation. Many variables that actuaries use are on numerical scales, like age or year, which require parameters at…

Applications · Statistics 2020-12-22 Gary Venter , Şule Şahin