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Accurate quantification of the geometry of curvilinear biological structures is essential for understanding cellular mechanics and disease-related morphological alterations. Microtubule curvature is a key descriptor of filament rigidity and…
Skull stripping magnetic resonance images (MRI) of the human brain is an important process in many image processing techniques, such as automatic segmentation of brain structures. Numerous methods have been developed to perform this task,…
Human face images usually appear with wide range of visual scales. The existing face representations pursue the bandwidth of handling scale variation via multi-scale scheme that assembles a finite series of predefined scales. Such…
The boundary representation (B-Rep) models a 3D solid as its explicit boundaries: trimmed corners, edges, and faces. Recovering B-Rep representation from unstructured data is a challenging and valuable task of computer vision and graphics.…
Whole brain extraction, also known as skull stripping, is a process in neuroimaging in which non-brain tissue such as skull, eyeballs, skin, etc. are removed from neuroimages. Skull striping is a preliminary step in presurgical planning,…
Adolescent idiopathic scoliosis (AIS) is a lifetime disease that arises in children. Accurate estimation of Cobb angles of the scoliosis is essential for clinicians to make diagnosis and treatment decisions. The Cobb angles are measured…
This study's objective was to segment spinal metastases in diagnostic MR images using a deep learning-based approach. Segmentation of such lesions can present a pivotal step towards enhanced therapy planning and validation, as well as…
In clinical settings, the screening, diagnosis, and monitoring of adolescent idiopathic scoliosis (AIS) typically involve physical or radiographic examinations. However, physical examinations are subjective, while radiographic examinations…
Accurate segmentation of 3D clinical medical images is critical in the diagnosis and treatment of spinal diseases. However, the inherent complexity of spinal anatomy and uncertainty inherent in current imaging technologies, poses…
This paper introduces a novel multimodal and high-resolution human brain cerebellum lobule segmentation method. Unlike current tools that operate at standard resolution ($1 \text{ mm}^{3}$) or using mono-modal data, the proposed method…
State-of-the-art brain tumor segmentation is based on deep learning models applied to multi-modal MRIs. Currently, these models are trained on images after a preprocessing stage that involves registration, interpolation, brain extraction…
Point cloud registration, a fundamental task in 3D computer vision, has remained largely unexplored in cross-source point clouds and unstructured scenes. The primary challenges arise from noise, outliers, and variations in scale and…
Point cloud analysis without pose priors is very challenging in real applications, as the orientations of point clouds are often unknown. In this paper, we propose a brand new point-set learning framework PRIN, namely, Point-wise Rotation…
Boundary Representation (B-Rep) is the de facto representation of 3D solids in Computer-Aided Design (CAD). B-Rep solids are defined with a set of NURBS (Non-Uniform Rational B-Splines) surfaces forming a closed volume. To represent a…
Bayesian optimization is a popular method for optimizing expensive black-box functions. Yet it oftentimes struggles in high dimensions where the computation could be prohibitively heavy. To alleviate this problem, we introduce Coordinate…
Deep model-based architectures (DMBAs) integrating physical measurement models and learned image regularizers are widely used in parallel magnetic resonance imaging (PMRI). Traditional DMBAs for PMRI rely on pre-estimated coil sensitivity…
In many scenarios, especially biomedical applications, the correct delineation of complex fine-scaled structures such as neurons, tissues, and vessels is critical for downstream analysis. Despite the strong predictive power of deep learning…
Physics-informed machine learning offers a promising framework for solving complex partial differential equations (PDEs) by integrating observational data with governing physical laws. However, learning PDEs with varying parameters and…
Deep learning-based automatic segmentation methods have become state-of-the-art. However, they are often not robust enough for direct clinical application, as domain shifts between training and testing data affect their performance. Failure…
In this paper we introduce a new method for automatically selecting knots in spline regression. The approach consists in setting a large number of initial knots and fitting the spline regression through a penalized likelihood procedure…