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The ongoing explosion of genome sequence data is transforming how we reconstruct and understand the histories of biological systems. Across biological scales, from individual cells to populations and species, trees-based models provide a…

Populations and Evolution · Quantitative Biology 2025-12-08 Yun Deng , Shing H. Zhan , Yulin Zhang , Chao Zhang , Bingjie Chen

Generative Autoregressive Neural Networks (ARNNs) have recently demonstrated exceptional results in image and language generation tasks, contributing to the growing popularity of generative models in both scientific and commercial…

Disordered Systems and Neural Networks · Physics 2024-03-26 Indaco Biazzo

Disease-gene prediction (DGP) refers to the computational challenge of predicting associations between genes and diseases. Effective solutions to the DGP problem have the potential to accelerate the therapeutic development pipeline at early…

Machine Learning · Computer Science 2019-07-15 Vikash Singh , Pietro Lio'

Data selection methods, such as active learning and core-set selection, are useful tools for improving the data efficiency of deep learning models on large-scale datasets. However, recent deep learning models have moved forward from…

Machine Learning · Computer Science 2021-08-03 Wentao Zhang , Zhi Yang , Yexin Wang , Yu Shen , Yang Li , Liang Wang , Bin Cui

Deep neural networks (DNNs) have become ubiquitous in addressing a number of problems, particularly in computer vision. However, DNN inference is computationally intensive, which can be prohibitive e.g. when considering edge devices. To…

Computer Vision and Pattern Recognition · Computer Science 2023-11-20 Rémi Ouazan Reboul , Edouard Yvinec , Arnaud Dapogny , Kevin Bailly

This paper introduces Diffuse-TreeVAE, a deep generative model that integrates hierarchical clustering into the framework of Denoising Diffusion Probabilistic Models (DDPMs). The proposed approach generates new images by sampling from a…

Machine Learning · Computer Science 2024-07-15 Jorge da Silva Goncalves , Laura Manduchi , Moritz Vandenhirtz , Julia E. Vogt

Probability estimation of tree topologies is one of the fundamental tasks in phylogenetic inference. The recently proposed subsplit Bayesian networks (SBNs) provide a powerful probabilistic graphical model for tree topology probability…

Populations and Evolution · Quantitative Biology 2024-09-10 Tianyu Xie , Musu Yuan , Minghua Deng , Cheng Zhang

The goal of this thesis is to improve our understanding of the internal mechanisms by which deep artificial neural networks create meaningful representations and are able to generalize. We focus on the challenge of characterizing the…

Machine Learning · Computer Science 2025-10-29 Diego Doimo

Recent years have seen a rapid expansion of the model space explored in statistical phylogenetics, emphasizing the need for new approaches to statistical model representation and software development. Clear communication and representation…

Populations and Evolution · Quantitative Biology 2013-12-10 Sebastian Höhna , Tracy A. Heath , Bastien Boussau , Michael J. Landis , Fredrik Ronquist , John P. Huelsenbeck

Autoregressive (AR) image models achieve diffusion-level quality but suffer from sequential inference, requiring approximately 2,000 steps for a 576x576 image. Speculative decoding with draft trees accelerates LLMs yet underperforms on…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Haodong Lei , Hongsong Wang , Xin Geng , Liang Wang , Pan Zhou

Most deep learning models are limited to specific datasets or tasks because of network structures using fixed layers. In this paper, we discuss the differences between existing neural networks and real human neurons, propose association…

Artificial Intelligence · Computer Science 2023-01-31 Seokjun Kim , Jaeeun Jang , Hyeoncheol Kim

The problem of modeling forest tree growth curves with an artificial neural network (NN) is examined. The NN parametric form is shown to be a suitable model if each forest tree plot is assumed to consist of several differently growing…

Data Analysis, Statistics and Probability · Physics 2007-05-23 Christopher Gordon

Construction of phylogenetic trees and networks for extant species from their characters represents one of the key problems in phylogenomics. While solution to this problem is not always uniquely defined and there exist multiple methods for…

Populations and Evolution · Quantitative Biology 2016-08-10 Nikita Alexeev , Max A. Alekseyev

Graph neural networks (GNNs) have shown advantages in graph-based analysis tasks. However, most existing methods have the homogeneity assumption and show poor performance on heterophilic graphs, where the linked nodes have dissimilar…

Machine Learning · Computer Science 2024-04-16 Tianhao Peng , Wenjun Wu , Haitao Yuan , Zhifeng Bao , Zhao Pengrui , Xin Yu , Xuetao Lin , Yu Liang , Yanjun Pu

Recent years have witnessed the impressive progress in Neural Dependency Parsing. According to the different factorization approaches to the graph joint probabilities, existing parsers can be roughly divided into autoregressive and…

Computation and Language · Computer Science 2023-06-22 Ye Ma , Mingming Sun , Ping Li

Reconstructing the tree of life from molecular sequences is a fundamental problem in computational biology. Modern data sets often contain a large number of genes, which can complicate the reconstruction problem due to the fact that…

Probability · Mathematics 2017-07-21 Constantinos Daskalakis , Sebastien Roch

We analyze dynamic random network models where younger vertices connect to older ones with probabilities proportional to their degrees as well as a propensity kernel governed by their attribute types. Using stochastic approximation…

Probability · Mathematics 2025-10-29 Nelson Antunes , Sayan Banerjee , Shankar Bhamidi , Vladas Pipiras

We propose methods to improve the forecasts from generalized autoregressive score (GAS) models (Creal et. al, 2013; Harvey, 2013) by localizing their parameters using decision trees and random forests. These methods avoid the curse of…

Econometrics · Economics 2023-05-31 Andrew J. Patton , Yasin Simsek

The evolutionary relationships among organisms have traditionally been represented using rooted phylogenetic trees. However, due to reticulate processes such as hybridization or lateral gene transfer, evolution cannot always be adequately…

Populations and Evolution · Quantitative Biology 2022-01-20 Sungsik Kong , Joan Carles Pons , Laura Kubatko , Kristina Wicke

We present an approach to adaptively utilize deep neural networks in order to reduce the evaluation time on new examples without loss of accuracy. Rather than attempting to redesign or approximate existing networks, we propose two schemes…

Machine Learning · Computer Science 2017-09-20 Tolga Bolukbasi , Joseph Wang , Ofer Dekel , Venkatesh Saligrama