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In single-cell research, tracing and analyzing high-throughput single-cell differentiation trajectories is crucial for understanding biological processes. Key to this is the robust modeling of hierarchical structures that govern cellular…

Machine Learning · Computer Science 2026-05-19 Zelin Zang , WenZhe Li , Yongjie Xu , Chang Yu , Changxi Chi , Jingbo Zhou , Zhen Lei , Stan Z. Li

The complex correlation structure of a collection of orthologous DNA sequences is uniquely captured by the "ancestral recombination graph" (ARG), a complete record of coalescence and recombination events in the history of the sample.…

Populations and Evolution · Quantitative Biology 2013-12-04 Matthew D. Rasmussen , Melissa J. Hubisz , Ilan Gronau , Adam Siepel

Vector autoregression has been widely used for modeling and analysis of multivariate time series data. In high-dimensional settings, model parameter regularization schemes inducing sparsity yield interpretable models and achieved good…

Methodology · Statistics 2023-06-08 Leo L. Duan , Zeyu Yuwen , George Michailidis , Zhengwu Zhang

Tree-based phylogenetic networks, which may be roughly defined as leaf-labeled networks built by adding arcs only between the original tree edges, have elegant properties for modeling evolutionary histories. We answer an open question of…

Adaptable models could greatly benefit robotic agents operating in the real world, allowing them to deal with novel and varying conditions. While approaches such as Bayesian inference are well-studied frameworks for adapting models to…

Machine Learning · Computer Science 2023-10-20 Orr Krupnik , Elisei Shafer , Tom Jurgenson , Aviv Tamar

Deep feedforward neural networks (DFNNs) are a powerful tool for functional approximation. We describe flexible versions of generalized linear and generalized linear mixed models incorporating basis functions formed by a DFNN. The…

Computation · Statistics 2018-05-28 Minh-Ngoc Tran , Nghia Nguyen , David Nott , Robert Kohn

This paper proposes a new algorithm for learning accurate tree-based models while ensuring the existence of recourse actions. Algorithmic Recourse (AR) aims to provide a recourse action for altering the undesired prediction result given by…

Machine Learning · Computer Science 2024-06-04 Kentaro Kanamori , Takuya Takagi , Ken Kobayashi , Yuichi Ike

Generative recommendation (GR) models generate items by autoregressively producing a sequence of discrete tokens that jointly index the target item. However, this autoregressive generation process also induces a structured decoding space…

Information Retrieval · Computer Science 2026-05-08 Yupeng Hou , Haven Kim , Clark Mingxuan Ju , Eduardo Escoto , Neil Shah , Julian McAuley

Designing plausible network models typically requires scholars to form a priori intuitions on the key drivers of network formation. Oftentimes, these intuitions are supported by the statistical estimation of a selection of network evolution…

Social and Information Networks · Computer Science 2019-07-01 Telmo Menezes , Camille Roth

Neural architectures can be naturally viewed as computational graphs. Motivated by this perspective, we, in this paper, study neural architecture search (NAS) through the lens of learning random graph models. In contrast to existing NAS…

Machine Learning · Computer Science 2022-11-29 Muchen Li , Jeffrey Yunfan Liu , Leonid Sigal , Renjie Liao

Since the advent of modern bioinformatics, the challenging, multifaceted problem of reconstructing phylogenetic history from biological sequences has hatched perennial statistical and algorithmic innovation. Studies of the phylogenetic…

Data Structures and Algorithms · Computer Science 2024-03-05 Matthew Andres Moreno , Santiago Rodriguez Papa , Emily Dolson

In this paper, we aim at establishing an approximation theory and a learning theory of distribution regression via a fully connected neural network (FNN). In contrast to the classical regression methods, the input variables of distribution…

Machine Learning · Statistics 2023-07-10 Zhongjie Shi , Zhan Yu , Ding-Xuan Zhou

We introduce Graph-Induced Sum-Product Networks (GSPNs), a new probabilistic framework for graph representation learning that can tractably answer probabilistic queries. Inspired by the computational trees induced by vertices in the context…

Machine Learning · Computer Science 2024-02-19 Federico Errica , Mathias Niepert

In this work a novel, automated process for constructing and initializing deep feed-forward neural networks based on decision trees is presented. The proposed algorithm maps a collection of decision trees trained on the data into a…

Machine Learning · Computer Science 2018-07-04 K. D. Humbird , J. L. Peterson , R. G. McClarren

Rooted phylogenetic networks are used by biologists to infer and represent complex evolutionary relationships between species that cannot be accurately explained by a phylogenetic tree. Tree-child networks are a particular class of rooted…

Combinatorics · Mathematics 2024-09-02 Janosch Döcker , Simone Linz

Rooted phylogenetic networks provide a more complete representation of the ancestral relationship between species than phylogenetic trees when reticulate evolutionary processes are at play. One way to reconstruct a phylogenetic network is…

Combinatorics · Mathematics 2020-12-02 Allan Bai , Peter Erdos , Charles Semple , Mike Steel

Graphs are fundamental data structures which concisely capture the relational structure in many important real-world domains, such as knowledge graphs, physical and social interactions, language, and chemistry. Here we introduce a powerful…

Machine Learning · Computer Science 2018-03-12 Yujia Li , Oriol Vinyals , Chris Dyer , Razvan Pascanu , Peter Battaglia

In this work, we propose a graph-adaptive pruning (GAP) method for efficient inference of convolutional neural networks (CNNs). In this method, the network is viewed as a computational graph, in which the vertices denote the computation…

Computer Vision and Pattern Recognition · Computer Science 2018-11-22 Mengdi Wang , Qing Zhang , Jun Yang , Xiaoyuan Cui , Wei Lin

Phylogenetics uses alignments of molecular sequence data to learn about evolutionary trees. Substitutions in sequences are modelled through a continuous-time Markov process, characterised by an instantaneous rate matrix, which standard…

Populations and Evolution · Quantitative Biology 2020-07-20 Naomi E. Hannaford , Sarah E. Heaps , Tom M. W. Nye , Tom A. Williams , T. Martin Embley

Taxonomy is formulated as directed acyclic concepts graphs or trees that support many downstream tasks. Many new coming concepts need to be added to an existing taxonomy. The traditional taxonomy expansion task aims only at finding the best…

Artificial Intelligence · Computer Science 2023-03-28 Zhouhong Gu , Sihang Jiang , Jingping Liu , Yanghua Xiao , Hongwei Feng , Zhixu Li , Jiaqing Liang , Jian Zhong
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