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Attention-based sequential recommendation methods have shown promise in accurately capturing users' evolving interests from their past interactions. Recent research has also explored the integration of reinforcement learning (RL) into these…

Machine Learning · Computer Science 2024-04-19 Melissa Mozifian , Tristan Sylvain , Dave Evans , Lili Meng

Large language models (LLMs) have shown strong ability in generating rich representations across domains such as natural language processing and generation, computer vision, and multimodal learning. However, their application in biomedical…

Genomics · Quantitative Biology 2025-09-30 Luxuan Zhang , Douglas Jiang , Qinglong Wang , Haoqi Sun , Feng Tian

Modern neural recording techniques such as two-photon imaging or Neuropixel probes allow to acquire vast time-series datasets with responses of hundreds or thousands of neurons. Contrastive learning is a powerful self-supervised framework…

Recent empirical works have successfully used unlabeled data to learn feature representations that are broadly useful in downstream classification tasks. Several of these methods are reminiscent of the well-known word2vec embedding…

Machine Learning · Computer Science 2019-02-26 Sanjeev Arora , Hrishikesh Khandeparkar , Mikhail Khodak , Orestis Plevrakis , Nikunj Saunshi

While supervised learning has enabled great progress in many applications, unsupervised learning has not seen such widespread adoption, and remains an important and challenging endeavor for artificial intelligence. In this work, we propose…

Machine Learning · Computer Science 2019-01-23 Aaron van den Oord , Yazhe Li , Oriol Vinyals

Learning robust representations to discriminate cell phenotypes based on microscopy images is important for drug discovery. Drug development efforts typically analyse thousands of cell images to screen for potential treatments. Early works…

Computer Vision and Pattern Recognition · Computer Science 2021-12-28 Alexis Perakis , Ali Gorji , Samriddhi Jain , Krishna Chaitanya , Simone Rizza , Ender Konukoglu

High-throughput RNA-sequencing (RNA-seq) technologies are powerful tools for understanding cellular state. Often it is of interest to quantify and summarize changes in cell state that occur between experimental or biological conditions.…

Methodology · Statistics 2021-02-16 Andrew Jones , F. William Townes , Didong Li , Barbara E. Engelhardt

Incorporating contrastive learning objectives in sentence representation learning (SRL) has yielded significant improvements on many sentence-level NLP tasks. However, it is not well understood why contrastive learning works for learning…

Computation and Language · Computer Science 2023-05-30 Chenghao Xiao , Yang Long , Noura Al Moubayed

Link prediction tasks focus on predicting possible future connections. Most existing researches measure the likelihood of links by different similarity scores on node pairs and predict links between nodes. However, the similarity-based…

Machine Learning · Computer Science 2023-03-09 Zehua Zhang , Shilin Sun , Guixiang Ma , Caiming Zhong

Unsupervised sentence representation learning is one of the fundamental problems in natural language processing with various downstream applications. Recently, contrastive learning has been widely adopted which derives high-quality sentence…

Computation and Language · Computer Science 2023-05-29 Jiduan Liu , Jiahao Liu , Qifan Wang , Jingang Wang , Wei Wu , Yunsen Xian , Dongyan Zhao , Kai Chen , Rui Yan

Contrastive representation learning seeks to acquire useful representations by estimating the shared information between multiple views of data. Here, the choice of data augmentation is sensitive to the quality of learned representations:…

Machine Learning · Statistics 2023-01-18 Kyungmin Lee , Jinwoo Shin

The success of Transformer-based models has encouraged many researchers to learn CAD models using sequence-based approaches. However, learning CAD models is still a challenge, because they can be represented as complex shapes with long…

Computer Vision and Pattern Recognition · Computer Science 2024-04-03 Minseop Jung , Minseong Kim , Jibum Kim

Graph-level representations are critical in various real-world applications, such as predicting the properties of molecules. But in practice, precise graph annotations are generally very expensive and time-consuming. To address this issue,…

Machine Learning · Computer Science 2022-07-26 Shuai Lin , Pan Zhou , Zi-Yuan Hu , Shuojia Wang , Ruihui Zhao , Yefeng Zheng , Liang Lin , Eric Xing , Xiaodan Liang

Robotic systems that rely primarily on self-supervised learning have the potential to decrease the amount of human annotation and engineering effort required to learn control strategies. In the same way that prior robotic systems have…

Machine Learning · Computer Science 2025-06-11 Chongyi Zheng , Benjamin Eysenbach , Homer Walke , Patrick Yin , Kuan Fang , Ruslan Salakhutdinov , Sergey Levine

Despite pre-trained language models have proven useful for learning high-quality semantic representations, these models are still vulnerable to simple perturbations. Recent works aimed to improve the robustness of pre-trained models mainly…

Computation and Language · Computer Science 2021-07-02 Dong Wang , Ning Ding , Piji Li , Hai-Tao Zheng

Contrastive self-supervised learning has become a prominent technique in representation learning. The main step in these methods is to contrast semantically similar and dissimilar pairs of samples. However, in the domain of Natural Language…

Computation and Language · Computer Science 2022-06-07 Amrita Bhattacharjee , Mansooreh Karami , Huan Liu

Single-cell RNA sequencing (scRNA-seq) enables researchers to analyze gene expression at single-cell level. One important task in scRNA-seq data analysis is unsupervised clustering, which helps identify distinct cell types, laying down the…

Genomics · Quantitative Biology 2023-12-29 Weikang Jiang , Jinxian Wang , Jihong Guan , Shuigeng Zhou

Often we wish to transfer representational knowledge from one neural network to another. Examples include distilling a large network into a smaller one, transferring knowledge from one sensory modality to a second, or ensembling a…

Machine Learning · Computer Science 2022-01-26 Yonglong Tian , Dilip Krishnan , Phillip Isola

A fundamental property of DNA is that the reverse complement (RC) of a sequence often carries identical biological meaning. However, state-of-the-art DNA language models frequently fail to capture this symmetry, producing inconsistent…

Machine Learning · Computer Science 2025-09-24 Mingqian Ma

Recent self-supervised contrastive methods have been able to produce impressive transferable visual representations by learning to be invariant to different data augmentations. However, these methods implicitly assume a particular set of…

Computer Vision and Pattern Recognition · Computer Science 2021-03-22 Tete Xiao , Xiaolong Wang , Alexei A. Efros , Trevor Darrell
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