English
Related papers

Related papers: Kernel-Elastic Autoencoder for Molecular Design

200 papers

In recent years, the field of machine learning has made phenomenal progress in the pursuit of simulating real-world data generation processes. One notable example of such success is the variational autoencoder (VAE). In this work, with a…

Machine Learning · Statistics 2021-12-30 Hwan Goh , Sheroze Sheriffdeen , Jonathan Wittmer , Tan Bui-Thanh

Recent advances in latent diffusion models have demonstrated their effectiveness for high-resolution image synthesis. However, the properties of the latent space from tokenizer for better learning and generation of diffusion models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-06-02 Hao Chen , Yujin Han , Fangyi Chen , Xiang Li , Yidong Wang , Jindong Wang , Ze Wang , Zicheng Liu , Difan Zou , Bhiksha Raj

Knee Osteoarthritis (KOA) is a common musculoskeletal condition that significantly affects mobility and quality of life, particularly in elderly populations. However, training deep learning models for early KOA classification is often…

Image and Video Processing · Electrical Eng. & Systems 2025-01-17 Zhe Wang , Aladine Chetouani , Mohamed Jarraya , Yung Hsin Chen , Yuhua Ru , Fang Chen , Fabian Bauer , Liping Zhang , Didier Hans , Rachid Jennane

We introduce the concept of a Modular Autoencoder (MAE), capable of learning a set of diverse but complementary representations from unlabelled data, that can later be used for supervised tasks. The learning of the representations is…

Machine Learning · Computer Science 2015-11-24 Henry W J Reeve , Gavin Brown

An autoencoder (AE) is a neural network that, using self-supervised training, learns a succinct parameterized representation, and a corresponding encoding and decoding process, for all instances in a given class. Here, we introduce the…

Machine Learning · Computer Science 2025-07-15 Assaf Marron , Smadar Szekely , Irun Cohen , David Harel

Auto-encoder is a special kind of neural network based on reconstruction. De-noising auto-encoder (DAE) is an improved auto-encoder which is robust to the input by corrupting the original data first and then reconstructing the original…

Machine Learning · Computer Science 2014-04-24 Fu-qiang Chen , Yan Wu , Guo-dong Zhao , Jun-ming Zhang , Ming Zhu , Jing Bai

Based on the traditional VAE, a novel neural network model is presented, with the latest molecular representation, SELFIES, to improve the effect of generating new molecules. In this model, multi-layer convolutional network and Fisher…

Biomolecules · Quantitative Biology 2023-05-03 Li Kai , Li Ning , Zhang Wei , Gao Ming

Channel Autoencoders (CAEs) have shown significant potential in optimizing the physical layer of a wireless communication system for a specific channel through joint end-to-end training. However, the practical implementation of CAEs faces…

Machine Learning · Computer Science 2025-02-11 Ali Owfi , Jonathan Ashdown , Kurt Turck , Fatemeh Afghah

De novo molecule design has become a highly active research area, advanced significantly through the use of state-of-the-art generative models. Despite these advances, several fundamental questions remain unanswered as the field…

Biomolecules · Quantitative Biology 2024-09-09 Heath Arthur-Loui , Amina Mollaysa , Michael Krauthammer

Optimal computations under uncertainty require an adequate probabilistic representation about beliefs. Deep generative models, and specifically Variational Autoencoders (VAEs), have the potential to meet this demand by building latent…

Predicting molecular conformations (or 3D structures) from molecular graphs is a fundamental problem in many applications. Most existing approaches are usually divided into two steps by first predicting the distances between atoms and then…

Machine Learning · Computer Science 2025-01-07 Minkai Xu , Wujie Wang , Shitong Luo , Chence Shi , Yoshua Bengio , Rafael Gomez-Bombarelli , Jian Tang

Variational autoencoders (VAEs) are powerful generative modelling methods, however they suffer from blurry generated samples and reconstructions compared to the images they have been trained on. Significant research effort has been spent to…

Computer Vision and Pattern Recognition · Computer Science 2023-04-13 Gustav Bredell , Kyriakos Flouris , Krishna Chaitanya , Ertunc Erdil , Ender Konukoglu

We propose a new class of physics-informed neural networks, called physics-informed Variational Autoencoder (PI-VAE), to solve stochastic differential equations (SDEs) or inverse problems involving SDEs. In these problems the governing…

Machine Learning · Statistics 2022-11-09 Weiheng Zhong , Hadi Meidani

An AI-powered quality engineering platform uses artificial intelligence to boost software quality assessments through automated defect prediction and optimized performance alongside improved feature extraction. Existing models result in…

Artificial Intelligence · Computer Science 2025-03-21 Seshu Babu Barma , Mohanakrishnan Hariharan , Satish Arvapalli

We present a novel masked image modeling (MIM) approach, context autoencoder (CAE), for self-supervised representation pretraining. We pretrain an encoder by making predictions in the encoded representation space. The pretraining tasks…

Computer Vision and Pattern Recognition · Computer Science 2023-08-11 Xiaokang Chen , Mingyu Ding , Xiaodi Wang , Ying Xin , Shentong Mo , Yunhao Wang , Shumin Han , Ping Luo , Gang Zeng , Jingdong Wang

In the last few years there have been important advancements in generative models with the two dominant approaches being Generative Adversarial Networks (GANs) and Variational Autoencoders (VAEs). However, standard Autoencoders (AEs) and…

Computer Vision and Pattern Recognition · Computer Science 2019-07-26 Massimiliano Patacchiola , Patrick Fox-Roberts , Edward Rosten

We introduce Quantum Molecular Autoencoder (MolQAE), the first quantum autoencoder to leverage the complete molecular structures. MolQAE uniquely maps SMILES strings directly to quantum states using parameterized rotation gates, preserving…

Quantum Physics · Physics 2025-06-02 Yi Pan , Hanqi Jiang , Wei Ruan , Dajiang Zhu , Xiang Li , Yohannes Abate , Yingfeng Wang , Tianming Liu

With the increasing use of high-precision system analysis programs in nuclear engineering, the number of high-fidelity computational data for accident simulation is exploding. Therefore, an algorithm that can achieve both automatic…

Signal Processing · Electrical Eng. & Systems 2022-08-30 Chengyuan Li , Meifu Li , Zhifang Qiu

This paper presents a novel convolutional neural network (CNN) based image compression framework via scalable auto-encoder (SAE). Specifically, our SAE based deep image codec consists of hierarchical coding layers, each of which is an…

Multimedia · Computer Science 2019-04-02 Chuanmin Jia , Zhaoyi Liu , Yao Wang , Siwei Ma , Wen Gao

Conditional Autoencoders (CAEs) offer a flexible, interpretable approach for estimating latent asset-pricing factors from firm characteristics. However, existing studies usually limit the latent factor dimension to around K=5 due to…

Portfolio Management · Quantitative Finance 2025-11-24 Ryan Engel , Yu Chen , Pawel Polak , Ioana Boier