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Data encoding is a common and central operation in most data analysis tasks. The performance of other models downstream in the computational process highly depends on the quality of data encoding. One of the most powerful ways to encode…

Machine Learning · Computer Science 2025-09-03 Teddy Lazebnik , Liron Simon-Keren

We present the enhanced feature quantum autoencoder, or EF-QAE, a variational quantum algorithm capable of compressing quantum states of different models with higher fidelity. The key idea of the algorithm is to define a parameterized…

Quantum Physics · Physics 2021-07-13 Carlos Bravo-Prieto

Developing effective representations of protein structures is essential for advancing protein science, particularly for protein generative modeling. Current approaches often grapple with the complexities of the SE(3) manifold, rely on…

Machine Learning · Computer Science 2025-10-14 Shaoning Li , Le Zhuo , Yusong Wang , Mingyu Li , Xinheng He , Fandi Wu , Hongsheng Li , Pheng-Ann Heng

In this paper, we investigate the problem of string-based molecular generation via variational autoencoders (VAEs) that have served a popular generative approach for various tasks in artificial intelligence. We propose a simple, yet…

Machine Learning · Computer Science 2022-08-24 Kisoo Kwon , Kuhwan Jung , Junghyun Park , Hwidong Na , Jinwoo Shin

Variational auto-encoders (VAEs) provide an attractive solution to image generation problem. However, they tend to produce blurred and over-smoothed images due to their dependence on pixel-wise reconstruction loss. This paper introduces a…

Computer Vision and Pattern Recognition · Computer Science 2018-04-30 Salman H. Khan , Munawar Hayat , Nick Barnes

The de novo design of drug molecules is recognized as a time-consuming and costly process, and computational approaches have been applied in each stage of the drug discovery pipeline. Variational autoencoder is one of the computer-aided…

Quantum Physics · Physics 2021-12-24 Junde Li , Swaroop Ghosh

Deep learning has significantly advanced and accelerated de novo molecular generation. Generative networks, namely Variational Autoencoders (VAEs) can not only randomly generate new molecules, but also alter molecular structures to optimize…

Biomolecules · Quantitative Biology 2022-05-04 Ryan J Richards , Austen M Groener

Materials informatics (MI), which uses artificial intelligence and data analysis techniques to improve the efficiency of materials development, is attracting increasing interest from industry. One of its main applications is the rapid…

Machine Learning · Computer Science 2023-02-07 Yoshihiro Osakabe , Akinori Asahara

Despite recent successes in synthesizing faces and bedrooms, existing generative models struggle to capture more complex image types, potentially due to the oversimplification of their latent space constructions. To tackle this issue,…

Machine Learning · Computer Science 2018-03-13 Wenling Shang , Kihyuk Sohn , Yuandong Tian

This paper shows that masked autoencoders (MAE) are scalable self-supervised learners for computer vision. Our MAE approach is simple: we mask random patches of the input image and reconstruct the missing pixels. It is based on two core…

Computer Vision and Pattern Recognition · Computer Science 2021-12-21 Kaiming He , Xinlei Chen , Saining Xie , Yanghao Li , Piotr Dollár , Ross Girshick

Variational autoencoders (VAEs) are fundamental for generative modeling and image reconstruction, yet their performance often struggles to maintain high fidelity in reconstructions. This study introduces a hybrid model, quantum variational…

Computer Vision and Pattern Recognition · Computer Science 2025-03-10 Farina Riaz , Fakhar Zaman , Hajime Suzuki , Sharif Abuadbba , David Nguyen

Autoencoders have been widely used for dimensional reduction and feature extraction. Various types of autoencoders have been proposed by introducing regularization terms. Most of these regularizations improve representation learning by…

Machine Learning · Computer Science 2020-06-26 Yuzhu Guo , Kang Pan , Simeng Li , Zongchang Han , Kexin Wang , Li Li

Although variational autoencoders (VAEs) represent a widely influential deep generative model, many aspects of the underlying energy function remain poorly understood. In particular, it is commonly believed that Gaussian encoder/decoder…

Machine Learning · Computer Science 2019-10-31 Bin Dai , David Wipf

Variational Autoencoders (VAEs) typically rely on a probabilistic decoder with a predefined likelihood, most commonly an isotropic Gaussian, to model the data conditional on latent variables. While convenient for optimization, this choice…

Machine Learning · Statistics 2025-04-29 Chen Xu , Qiang Wang , Lijun Sun

Variational autoencdoers (VAE) are a popular approach to generative modelling. However, exploiting the capabilities of VAEs in practice can be difficult. Recent work on regularised and entropic autoencoders have begun to explore the…

Machine Learning · Computer Science 2022-03-02 Gregory A. Daly , Jonathan E. Fieldsend , Gavin Tabor

Recent state-of-the-art autoencoder based generative models have an encoder-decoder structure and learn a latent representation with a pre-defined distribution that can be sampled from. Implementing the encoder networks of these models in a…

Machine Learning · Computer Science 2020-05-11 D. T. Braithwaite , M. O'Connor , W. B. Kleijn

The latent space of generative modeling is long dominated by the VAE encoder. The latents from the pretrained representation encoders (e.g., DINO, SigLIP, MAE) are previously considered inappropriate for generative modeling. Recently, RAE…

Artificial Intelligence · Computer Science 2026-04-03 Hu Yu , Hang Xu , Jie Huang , Zeyue Xue , Haoyang Huang , Nan Duan , Feng Zhao

The variational autoencoder (VAE) framework remains a popular option for training unsupervised generative models, especially for discrete data where generative adversarial networks (GANs) require workaround to create gradient for the…

Machine Learning · Computer Science 2019-04-24 Jason Chou , Gautam Hathi

Deep Learning (DL) is a two-step classification model that consists feature learning, generating feature representations using unsupervised ways and the supervised learning stage at the last step of model using at least two hidden layers on…

Machine Learning · Computer Science 2021-01-26 Gokhan Altan , Yakup Kutlu

Aerosol-cloud--radiation interactions remain among the most uncertain components of the Earth's climate system, in partdue to the high dimensionality of aerosol state representations and the difficulty of obtaining complete \textit{in situ}…

Atmospheric and Oceanic Physics · Physics 2025-10-14 Ehsan Saleh , Saba Ghaffari , Jeffrey H. Curtis , Lekha Patel , Peter A. Bosler , Nicole Riemer , Matthew West