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The Deep learning (DL) models for diagnosing breast cancer from mammographic images often operate as "black boxes", making it difficult for healthcare professionals to trust and understand their decision-making processes. The study presents…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Maryam Ahmed , Tooba Bibi , Rizwan Ahmed Khan , Sidra Nasir

The application of artificial intelligence (AI) in medical imaging has revolutionized diagnostic practices, enabling advanced analysis and interpretation of radiological data. This study presents a comprehensive evaluation of…

Image and Video Processing · Electrical Eng. & Systems 2025-07-22 Zhijin He , Alan B. McMillan

The generalized outcome-adaptive lasso (GOAL) is a variable selection for high-dimensional causal inference proposed by Bald\'e et al. [2023, {\em Biometrics} {\bfseries 79(1)}, 514--520]. When the dimension is high, it is now well…

Statistics Theory · Mathematics 2024-06-11 Ismaila Baldé

Lung cancer remains one of the leading causes of cancer-related mortality worldwide. Conventional computed tomography (CT) imaging, while essential for detection and staging, has limitations in distinguishing benign from malignant lesions…

Image and Video Processing · Electrical Eng. & Systems 2026-04-20 Baramee Sukumal , Aueaphum Aueawatthanaphisut

Gliomas are among the most aggressive cancers, characterized by high mortality rates and complex diagnostic processes. Existing studies on glioma diagnosis and classification often describe issues such as high variability in imaging data,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-30 Md. Abdur Rahman , Mohaimenul Azam Khan Raiaan , Arefin Ittesafun Abian , Yan Zhang , Mirjam Jonkman , Sami Azam

Computer aided diagnosis (CAD) of Breast Cancer (BRCA) images has been an active area of research in recent years. The main goals of this research is to develop reliable automatic methods for detecting and diagnosing different types of BRCA…

Image and Video Processing · Electrical Eng. & Systems 2020-03-20 Marco A. V. M. Grinet , Nuno M. Garcia , Ana I. R. Gouveia , Jose A. F. Moutinho , Abel J. P. Gomes

Deep learning has shown remarkable results for image analysis and is expected to aid individual treatment decisions in health care. To achieve this, deep learning methods need to be promoted from the level of mere associations to being able…

Machine Learning · Computer Science 2022-05-02 Wouter A. C. van Amsterdam , Marinus J. C. Eijkemans

This paper presents a new algorithm for automatic variables selection. In particular, using the Graphical Models properties it is possible to develop a method that can be used in the contest of large dataset. The advantage of this algorithm…

Machine Learning · Statistics 2022-01-17 Luigi Riso

Background: The high dimensionality of radiomic feature sets, the variability in radiomic feature types and potentially high computational requirements all underscore the need for an effective method to identify the smallest set of…

Artificial intelligence (AI) techniques have significant potential to enable effective, robust and automated image phenotyping including identification of subtle patterns. AI-based detection searches the image space to find the regions of…

Medical Physics · Physics 2022-01-17 Fereshteh Yousefirizi , Pierre Decazes , Amine Amyar , Su Ruan , Babak Saboury , Arman Rahmim

Radiomics aims to extract and analyze large numbers of quantitative features from medical images and is highly promising in staging, diagnosing, and predicting outcomes of cancer treatments. Nevertheless, several challenges need to be…

Machine Learning · Computer Science 2017-10-09 Zhiguo Zhou , Zhi-Jie Zhou , Hongxia Hao , Shulong Li , Xi Chen , You Zhang , Michael Folkert , Jing Wang

While lung cancer is the second most diagnosed form of cancer in men and women, a sufficiently early diagnosis can be pivotal in patient survival rates. Imaging-based, or radiomics-driven, detection methods have been developed to aid…

Neural and Evolutionary Computing · Computer Science 2017-10-23 Mohammad Javad Shafiee , Audrey G. Chung , Farzad Khalvati , Masoom A. Haider , Alexander Wong

In genomic studies, identifying biomarkers associated with a variable of interest is a major concern in biomedical research. Regularized approaches are classically used to perform variable selection in high-dimensional linear models.…

Methodology · Statistics 2020-07-22 Wencan Zhu , Céline Lévy-Leduc , Nils Ternès

Accurately predicting the treatment outcome plays a greatly important role in tailoring and adapting a treatment planning in cancer therapy. Although the development of different modalities and personalized medicine can greatly improve the…

Causal inference has been increasingly reliant on observational studies with rich covariate information. To build tractable causal procedures, such as the doubly robust estimators, it is imperative to first extract important features from…

Methodology · Statistics 2022-02-08 Dingke Tang , Dehan Kong , Wenliang Pan , Linbo Wang

In this study, a radiomics approach was extended to optical fluorescence molecular imaging data for tissue classification, termed 'optomics'. Fluorescence molecular imaging is emerging for precise surgical guidance during head and neck…

Brain metastases affect approximately between 20% and 40% of cancer patients and are commonly treated with radiotherapy or radiosurgery. Early prediction of recurrence following treatment could enable timely clinical intervention and…

Image and Video Processing · Electrical Eng. & Systems 2025-12-18 Ines Faria , Matheus Silva , Crystian Saraiva , Jose Soares , Victor Alves

Radiomics with deep learning models have become popular in computer-aided diagnosis and have outperformed human experts on many clinical tasks. Specifically, radiomic models based on artificial intelligence (AI) are using medical data…

Image and Video Processing · Electrical Eng. & Systems 2022-06-08 Ahmad Chaddad , Jiali li , Qizong Lu , Yujie Li , Idowu Paul Okuwobi , Camel Tanougast , Christian Desrosiers , Tamim Niazi

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Machine learning methods are used to discover complex nonlinear relationships in biological and medical data. However, sophisticated learning models are computationally unfeasible for data with millions of features. Here we introduce the…