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Purpose: To identify optimal classification methods for computed tomography (CT) radiomics-based preoperative prediction of clear cells renal cell carcinoma (ccRCC) grade. Methods and material: Seventy one ccRCC patients were included in…
Manual delineation of volumes of interest (VOIs) by experts is considered the gold-standard method in radiomics analysis. However, it suffers from inter- and intra-operator variability. A quantitative assessment of the impact of variations…
Motivation: Radiomics refers to the high-throughput mining of quantitative features from radiographic images. It is a promising field in that it may provide a non-invasive solution for screening and classification. Standard machine learning…
Objective: Radiomics, an emerging tool for medical image analysis, is potential towards precisely characterizing gastric cancer (GC). Whether using one-slice 2D annotation or whole-volume 3D annotation remains a long-time debate, especially…
Selection of covariates is crucial in the estimation of average treatment effects given observational data with high or even ultra-high dimensional pretreatment variables. Existing methods for this problem typically assume sparse linear…
Medical image retrieval is a valuable field for supporting clinical decision-making, yet current methods primarily support 2D images and require fully annotated queries, limiting clinical flexibility. To address this, we propose…
Multimodal machine learning integrating histopathology and molecular data shows promise for cancer prognostication. We systematically reviewed studies combining whole slide images (WSIs) and high-throughput omics to predict overall…
Rapid technological advances in radiation therapy have significantly improved dose delivery and tumor control for head and neck cancers. However, treatment-related toxicities caused by high-dose exposure to critical structures remain a…
Purpose: This study investigated how nodule segmentation and surrounding peritumoral regions influence radionics-based lung cancer classification. Methods: Using 3D CT scans with bounding box annotated nodules, we generated 3D segmentations…
Aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing malignancy and benignity specifically in endometrial cancer (EC) patients. A total of 83 EC patients from two centers, including 46…
Background: The reproducibility of machine-learning models in prostate cancer detection across different MRI vendors remains a significant challenge. Methods: This study investigates Support Vector Machines (SVM) and Random Forest (RF)…
Background: As an important branch of machine learning pipelines in medical imaging, radiomics faces two major challenges namely reproducibility and accessibility. In this work, we introduce open-radiomics, a set of radiomics datasets along…
Lung cancer remains the leading cause of cancer-related mortality worldwide, with survival strongly dependent on early detection. Standard-dose computed tomography (CT) screening using the Lung Imaging Reporting and Data System (Lung-RADS)…
Medical Informatics and the application of modern signal processing in the assistance of the diagnostic process in medical imaging is one of the more recent and active research areas today. This thesis addresses a variety of issues related…
Background. Radiomic features, derived from a region of interest (ROI) in medical images, are valuable as prognostic factors. Selecting an appropriate ROI is critical, and many recent studies have focused on leveraging multiple ROIs by…
Motivation: The size of available omics datasets is steadily increasing with technological advancement in recent years. While this increase in sample size can be used to improve the performance of relevant prediction tasks in healthcare,…
Radiomics has proven to be a powerful prognostic tool for cancer detection, and has previously been applied in lung, breast, prostate, and head-and-neck cancer studies with great success. However, these radiomics-driven methods rely on…
The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…
The potential benefits of applying machine learning methods to -omics data are becoming increasingly apparent, especially in clinical settings. However, the unique characteristics of these data are not always well suited to machine learning…
'Radiomics' is a method that extracts mineable quantitative features from radiographic images. These features can then be used to determine prognosis, for example, predicting the development of distant metastases (DM). Existing radiomics…