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Related papers: Latent Diffusion Model for DNA Sequence Generation

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In this paper, we introduce the first diffusion model designed to generate complete synthetic human genotypes, which, by standard protocols, one can straightforwardly expand into full-length, DNA-level genomes. The synthetic genotypes mimic…

Computational Engineering, Finance, and Science · Computer Science 2025-01-31 Philip Kenneweg , Raghuram Dandinasivara , Xiao Luo , Barbara Hammer , Alexander Schönhuth

Existing generative models for unsupervised anomalous sound detection are limited by their inability to fully capture the complex feature distribution of normal sounds, while the potential of powerful diffusion models in this domain remains…

Sound · Computer Science 2026-02-03 Chengyuan Ma , Peng Jia , Hongyue Guo , Wenming Yang

Network data analytics are now at the core of almost every networking solution. Nonetheless, limited access to networking data has been an enduring challenge due to many reasons including complexity of modern networks, commercial…

Networking and Internet Architecture · Computer Science 2023-10-10 Nirhoshan Sivaroopan , Dumindu Bandara , Chamara Madarasingha , Guilluame Jourjon , Anura Jayasumana , Kanchana Thilakarathna

Recent advances in generative modeling, namely Diffusion models, have revolutionized generative modeling, enabling high-quality image generation tailored to user needs. This paper proposes a framework for the generative design of structural…

Large, pretrained latent diffusion models (LDMs) have demonstrated an extraordinary ability to generate creative content, specialize to user data through few-shot fine-tuning, and condition their output on other modalities, such as semantic…

Computer Vision and Pattern Recognition · Computer Science 2024-08-01 Yuru Jia , Lukas Hoyer , Shengyu Huang , Tianfu Wang , Luc Van Gool , Konrad Schindler , Anton Obukhov

Latent dynamical models are commonly used to learn the distribution of a latent dynamical process that represents a sequence of noisy data samples. However, producing samples from such models with high fidelity is challenging due to the…

Machine Learning · Computer Science 2023-08-17 Mohammad R. Rezaei

Single-cell RNA sequencing (scRNA-seq) data are important for studying the laws of life at single-cell level. However, it is still challenging to obtain enough high-quality scRNA-seq data. To mitigate the limited availability of data,…

Quantitative Methods · Quantitative Biology 2024-03-06 Erpai Luo , Minsheng Hao , Lei Wei , Xuegong Zhang

Low-field to high-field MRI synthesis has emerged as a cost-effective strategy to enhance image quality under hardware and acquisition constraints, particularly in scenarios where access to high-field scanners is limited or impractical.…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Zhenxuan Zhang , Peiyuan Jing , Ruicheng Yuan , Liwei Hu , Anbang Wang , Fanwen Wang , Yinzhe Wu , Kh Tohidul Islam , Zhaolin Chen , Zi Wang , Peter Lally , Guang Yang

Discrete diffusion models are a powerful class of generative models with strong performance across many domains. For efficiency, however, discrete diffusion typically parameterizes the generative (reverse) process with factorized…

Machine Learning · Statistics 2026-05-19 Grigory Bartosh , Teodora Pandeva , Sushrut Karmalkar , Javier Zazo

We introduce Efficient Motion Diffusion Model (EMDM) for fast and high-quality human motion generation. Current state-of-the-art generative diffusion models have produced impressive results but struggle to achieve fast generation without…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Wenyang Zhou , Zhiyang Dou , Zeyu Cao , Zhouyingcheng Liao , Jingbo Wang , Wenjia Wang , Yuan Liu , Taku Komura , Wenping Wang , Lingjie Liu

Deep generative models have emerged as promising tools for detecting arbitrary anomalies in data, dispensing with the necessity for manual labelling. Recently, autoregressive transformers have achieved state-of-the-art performance for…

Generative models, especially diffusion models (DMs), have achieved promising results for generating feature-rich geometries and advancing foundational science problems such as molecule design. Inspired by the recent huge success of Stable…

Machine Learning · Computer Science 2023-05-03 Minkai Xu , Alexander Powers , Ron Dror , Stefano Ermon , Jure Leskovec

Single-cell RNA-seq profiles are high-dimensional, sparse, and unordered, causing autoregressive generation to impose an artificial ordering bias and suffer from error accumulation. To address this, we propose scDiVa, a masked discrete…

Machine Learning · Computer Science 2026-02-04 Mingxuan Wang , Cheng Chen , Gaoyang Jiang , Zijia Ren , Chuangxin Zhao , Lu Shi , Yanbiao Ma

Effectively addressing the challenge of industrial Anomaly Detection (AD) necessitates an ample supply of defective samples, a constraint often hindered by their scarcity in industrial contexts. This paper introduces a novel algorithm…

Computer Vision and Pattern Recognition · Computer Science 2024-03-27 Hanxi Li , Zhengxun Zhang , Hao Chen , Lin Wu , Bo Li , Deyin Liu , Mingwen Wang

Generative diffusion models have achieved remarkable success in producing high-quality images. However, these models typically operate in continuous intensity spaces, diffusing independently across pixels and color channels. As a result,…

Graphics · Computer Science 2025-05-20 Javier E. Santos , Agnese Marcato , Roman Colman , Nicholas Lubbers , Yen Ting Lin

Diffusion models are rising as a powerful solution for high-fidelity image generation, which exceeds GANs in quality in many circumstances. However, their slow training and inference speed is a huge bottleneck, blocking them from being used…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Hao Phung , Quan Dao , Anh Tran

Designing protein sequences with specific biological functions and structural stability is crucial in biology and chemistry. Generative models already demonstrated their capabilities for reliable protein design. However, previous models are…

Machine Learning · Computer Science 2024-02-28 Lin Zongying , Li Hao , Lv Liuzhenghao , Lin Bin , Zhang Junwu , Chen Calvin Yu-Chian , Yuan Li , Tian Yonghong

Recent advances in deep learning demonstrate the ability to generate synthetic gaze data. However, most approaches have primarily focused on generating data from random noise distributions or global, predefined latent embeddings, whereas…

Human-Computer Interaction · Computer Science 2025-11-14 Kamrul Hasan , Dmytro Katrychuk , Mehedi Hasan Raju , Oleg V. Komogortsev

Snapshot compressive spectral imaging reconstruction aims to reconstruct three-dimensional spatial-spectral images from a single-shot two-dimensional compressed measurement. Existing state-of-the-art methods are mostly based on deep…

Image and Video Processing · Electrical Eng. & Systems 2024-08-27 Zongliang Wu , Ruiying Lu , Ying Fu , Xin Yuan

A robust face recognition model must be trained using datasets that include a large number of subjects and numerous samples per subject under varying conditions (such as pose, expression, age, noise, and occlusion). Due to ethical and…

Computer Vision and Pattern Recognition · Computer Science 2024-09-06 Bernardo Biesseck , Pedro Vidal , Luiz Coelho , Roger Granada , David Menotti|