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Many neuroscientific applications require robust and accurate localization of neurons. It is still an unsolved problem because of the enormous variation in intensity, texture, spatial overlap, morphology and background artifacts. In…

Quantitative Methods · Quantitative Biology 2021-03-22 Tamal Batabyal , Aijaz Ahmad Naik , Daniel Weller , Jaideep Kapur

Modern methods often formulate the counting of cells from microscopic images as a regression problem and more or less rely on expensive, manually annotated training images (e.g., dot annotations indicating the centroids of cells or…

Image and Video Processing · Electrical Eng. & Systems 2021-05-18 Xin Ding , Qiong Zhang , William J. Welch

We present a novel machine learning approach to understanding conformation dynamics of biomolecules. The approach combines kernel-based techniques that are popular in the machine learning community with transfer operator theory for…

Computational Physics · Physics 2019-01-24 Stefan Klus , Andreas Bittracher , Ingmar Schuster , Christof Schütte

Microscopy images from different imaging conditions, organs, and tissues often have numerous cells with various shapes on a range of backgrounds. As a result, designing a deep learning model to count cells in a source domain becomes…

Computer Vision and Pattern Recognition · Computer Science 2023-03-21 Zuhui Wang

Biological cells, by definition, are the basic units which contain the fundamental molecules of life of which all living things are composed. Understanding how they function and differentiating cells from one another therefore is of…

Signal Processing · Electrical Eng. & Systems 2021-01-07 Hassan Raji , Muhammad Tayyab , Jianye Sui , Seyed Reza Mahmoodi , Mehdi Javanmard

The interest for change detection in the field of remote sensing has increased in the last few years. Searching for changes in satellite images has many useful applications, ranging from land cover and land use analysis to anomaly…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Antonio Di Pilato , Nicolò Taggio , Alexis Pompili , Michele Iacobellis , Adriano Di Florio , Davide Passarelli , Sergio Samarelli

Extended object tracking involves estimating both the physical extent and kinematic parameters of a target object, where typically multiple measurements are observed per time step. In this article, we propose a deterministic closed-form…

Signal Processing · Electrical Eng. & Systems 2025-12-17 Simon Steuernagel , Marcus Baum

Lack of enough labeled data is a major problem in building machine learning based models when the manual annotation (labeling) is error-prone, expensive, tedious, and time-consuming. In this paper, we introduce an iterative deep learning…

Computer Vision and Pattern Recognition · Computer Science 2019-01-15 Saeed S. Alahmari , Dmitry Goldgof , Lawrence O. Hall , Palak Dave , Hady Ahmady Phoulady , Peter R. Mouton

With the recent advances in the object detection research field, tracking-by-detection has become the leading paradigm adopted by multi-object tracking algorithms. By extracting different features from detected objects, those algorithms can…

Computer Vision and Pattern Recognition · Computer Science 2020-07-14 Michel Meneses , Leonardo Matos , Bruno Prado , André de Carvalho , Hendrik Macedo

U-Net and its variants have been demonstrated to work sufficiently well in biological cell tracking and segmentation. However, these methods still suffer in the presence of complex processes such as collision of cells, mitosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-10-22 Deepak K. Gupta , Nathan de Bruijn , Andreas Panteli , Efstratios Gavves

In the field of state-of-the-art object detection, the task of object localization is typically accomplished through a dedicated subnet that emphasizes bounding box regression. This subnet traditionally predicts the object's position by…

Computer Vision and Pattern Recognition · Computer Science 2023-07-20 Peng Zhi , Haoran Zhou , Hang Huang , Rui Zhao , Rui Zhou , Qingguo Zhou

Autonomous driving requires various computer vision algorithms, such as object detection and tracking.Precisely-labeled datasets (i.e., objects are fully contained in bounding boxes with only a few extra pixels) are preferred for training…

Computer Vision and Pattern Recognition · Computer Science 2019-09-13 Govind Rathore , Wan-Yi Lin , Ji Eun Kim

The living body is composed of innumerable fine and complex structures and although these structures have been studied in the past, a vast amount of information pertaining to them still remains unknown. When attempting to observe these…

Medical Physics · Physics 2021-11-30 Raku Son , Kenji Yamazawa , Akiko Oguchi , Mitsuo Suga , Masaru Tamura , Yasuhiro Murakawa , Satoshi Kume

Deep learning based visual trackers entail offline pre-training on large volumes of video datasets with accurate bounding box annotations that are labor-expensive to achieve. We present a new framework to facilitate bounding box annotations…

Computer Vision and Pattern Recognition · Computer Science 2021-08-10 Kenan Dai , Jie Zhao , Lijun Wang , Dong Wang , Jianhua Li , Huchuan Lu , Xuesheng Qian , Xiaoyun Yang

The automatic detection of White Blood Cells (WBC) still remains as an unsolved issue in medical imaging. The analysis of WBC images has engaged researchers from fields of medicine and computer vision alike. Since WBC can be approximated by…

Computer Vision and Pattern Recognition · Computer Science 2014-06-30 Erik Cuevas , Margarita Diaz , Miguel Manzanares , Daniel Zaldivar , Marco Perez

Object detection generally requires sliding-window classifiers in tradition or anchor box based predictions in modern deep learning approaches. However, either of these approaches requires tedious configurations in boxes. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2021-11-09 Wei Liu , Irtiza Hasan , Shengcai Liao

Cell segmentation in histopathological images is vital for diagnosis, and treatment of several diseases. Annotating data is tedious, and requires medical expertise, making it difficult to employ supervised learning. Instead, we study a…

Computer Vision and Pattern Recognition · Computer Science 2025-11-06 Aayush Kumar Tyagi , Vaibhav Mishra , Prathosh A. P. , Mausam

This paper introduces a novel deep learning based approach for vision based single target tracking. We address this problem by proposing a network architecture which takes the input video frames and directly computes the tracking score for…

Computer Vision and Pattern Recognition · Computer Science 2016-07-12 Mengyao Zhai , Mehrsan Javan Roshtkhari , Greg Mori

Training object class detectors typically requires a large set of images in which objects are annotated by bounding-boxes. However, manually drawing bounding-boxes is very time consuming. We propose a new scheme for training object…

Computer Vision and Pattern Recognition · Computer Science 2017-04-25 Dim P. Papadopoulos , Jasper R. R. Uijlings , Frank Keller , Vittorio Ferrari

We propose a novel weakly supervised method to improve the boundary of the 3D segmented nuclei utilizing an over-segmented image. This is motivated by the observation that current state-of-the-art deep learning methods do not result in…

Computer Vision and Pattern Recognition · Computer Science 2021-08-31 S. Shailja , Jiaxiang Jiang , B. S. Manjunath
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