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Tracking cells and detecting mitotic events in time-lapse microscopy image sequences is a crucial task in biomedical research. However, it remains highly challenging due to dividing objects, low signal-tonoise ratios, indistinct boundaries,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Zhu Chen , Mert Edgü , Er Jin , Johannes Stegmaier

This paper explores object detection in the small data regime, where only a limited number of annotated bounding boxes are available due to data rarity and annotation expense. This is a common challenge today with machine learning being…

Computer Vision and Pattern Recognition · Computer Science 2019-10-17 Lanlan Liu , Michael Muelly , Jia Deng , Tomas Pfister , Li-Jia Li

The task object tracking is vital in numerous applications such as autonomous driving, intelligent surveillance, robotics, etc. This task entails the assigning of a bounding box to an object in a video stream, given only the bounding box…

Computer Vision and Pattern Recognition · Computer Science 2020-12-18 Vladislav Belyaev , Aleksandra Malysheva , Aleksei Shpilman

Segmentation is a fundamental process in microscopic cell image analysis. With the advent of recent advances in deep learning, more accurate and high-throughput cell segmentation has become feasible. However, most existing deep…

Computer Vision and Pattern Recognition · Computer Science 2020-06-25 Hyeonsoo Lee , Won-Ki Jeong

In this paper a novel biclustering algorithm based on artificial intelligence (AI) is introduced. The method called EBIC aims to detect biologically meaningful, order-preserving patterns in complex data. The proposed algorithm is probably…

Machine Learning · Computer Science 2018-07-27 Patryk Orzechowski , Moshe Sipper , Xiuzhen Huang , Jason H. Moore

Reliable quantitative analysis of immunohistochemical staining images requires accurate and robust cell detection and classification. Recent weakly-supervised methods usually estimate probability density maps for cell recognition. However,…

Computer Vision and Pattern Recognition · Computer Science 2022-07-04 Zhongyi Shui , Shichuan Zhang , Chenglu Zhu , Bingchuan Wang , Pingyi Chen , Sunyi Zheng , Lin Yang

In this study, we propose a novel extended target tracking algorithm which is capable of representing the extent of dynamic objects as an ellipsoid with a time-varying orientation angle. A diagonal positive semi-definite matrix is defined…

Machine Learning · Statistics 2021-04-21 Barkın Tuncer , Emre Özkan

Tracking all nuclei of an embryo in noisy and dense fluorescence microscopy data is a challenging task. We build upon a recent method for nuclei tracking that combines weakly-supervised learning from a small set of nuclei center point…

Computer Vision and Pattern Recognition · Computer Science 2022-08-25 Peter Hirsch , Caroline Malin-Mayor , Anthony Santella , Stephan Preibisch , Dagmar Kainmueller , Jan Funke

Network embeddings learn to represent nodes as low-dimensional vectors to preserve the proximity between nodes and communities of the network for network analysis. The temporal edges (e.g., relationships, contacts, and emails) in dynamic…

Social and Information Networks · Computer Science 2019-06-25 Chuanchang Chen , Yubo Tao , Hai Lin

In this paper, we propose a robust tracking method based on the collaboration of a generative model and a discriminative classifier, where features are learned by shallow and deep architectures, respectively. For the generative model, we…

Computer Vision and Pattern Recognition · Computer Science 2016-07-28 Bohan Zhuang , Lijun Wang , Huchuan Lu

High-throughput screening using cell images is an efficient method for screening new candidates for pharmaceutical drugs. To complete the screening process, it is essential to have an efficient process for analyzing cell images. This paper…

Computer Vision and Pattern Recognition · Computer Science 2024-02-28 Mizuki Fukasawa , Tomokazu Fukuda , Takuya Akashi

Data-efficient image classification is a challenging task that aims to solve image classification using small training data. Neural network-based deep learning methods are effective for image classification, but they typically require…

Neural and Evolutionary Computing · Computer Science 2022-12-05 Ying Bi , Bing Xue , Mengjie Zhang

Counting cells in fluorescent microscopy is a tedious, time-consuming task that researchers have to accomplish to assess the effects of different experimental conditions on biological structures of interest. Although such objects are…

Computer Vision and Pattern Recognition · Computer Science 2021-03-02 R. Morelli , L. Clissa , M. Dalla , M. Luppi , L. Rinaldi , A. Zoccoli

The current trend in object detection and localization is to learn predictions with high capacity deep neural networks trained on a very large amount of annotated data and using a high amount of processing power. In this work, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2016-11-18 Bastien Moysset , Christoper Kermorvant , Christian Wolf

Single-cell trajectory analysis aims to reconstruct the biological developmental processes of cells as they evolve over time, leveraging temporal correlations in gene expression. During cellular development, gene expression patterns…

Applications · Statistics 2026-03-30 Junhao Zhu , Kevin Zhang , Zhaolei Zhang , Dehan Kong

Conventional multi-stage cell tracking approaches rely heavily on detection or segmentation in each frame as a prerequisite, requiring substantial resources for high-quality segmentation masks and increasing the overall prediction time. To…

Image and Video Processing · Electrical Eng. & Systems 2025-10-14 Yaxuan Song , Jianan Fan , Heng Huang , Mei Chen , Weidong Cai

Tracking an unknown number of low-observable objects is notoriously challenging. This letter proposes a sequential Bayesian estimation method based on the track-before-detect (TBD) approach. In TBD, raw sensor measurements are directly used…

Signal Processing · Electrical Eng. & Systems 2023-07-04 Mingchao Liang , Thomas Kropfreiter , Florian Meyer

This paper presents a long-term object tracking framework with a moving event camera under general tracking conditions. A first of its kind for these revolutionary cameras, the tracking framework uses a discriminative representation for the…

Computer Vision and Pattern Recognition · Computer Science 2020-09-03 Bharath Ramesh , Shihao Zhang , Hong Yang , Andres Ussa , Matthew Ong , Garrick Orchard , Cheng Xiang

Deep neural networks have set the state-of-the-art in computer vision tasks such as bounding box detection and semantic segmentation. Object detectors and segmentation models assign confidence scores to predictions, reflecting the model's…

Computer Vision and Pattern Recognition · Computer Science 2026-03-16 Tobias J. Riedlinger , Kira Maag , Hanno Gottschalk

Instance segmentation of biological images is essential for studying object behaviors and properties. The challenges, such as clustering, occlusion, and adhesion problems of the objects, make instance segmentation a non-trivial task.…

Computer Vision and Pattern Recognition · Computer Science 2019-11-22 Jingru Yi , Hui Tang , Pengxiang Wu , Bo Liu , Daniel J. Hoeppner , Dimitris N. Metaxas , Lianyi Han , Wei Fan
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