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The development of noninvasive brain imaging such as resting-state functional magnetic resonance imaging (rs-fMRI) and its combination with AI algorithm provides a promising solution for the early diagnosis of Autism spectrum disorder…

Image and Video Processing · Electrical Eng. & Systems 2022-04-11 Fangyu Zhang , Yanjie Wei , Jin Liu , Yanlin Wang , Wenhui Xi , Yi Pan

Autism spectrum disorder (ASD) is a neurological and developmental disorder that affects social and communicative behaviors. It emerges in early life and is generally associated with lifelong disabilities. Thus, accurate and early diagnosis…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 Peiyu Duan , Nicha C. Dvornek , Jiyao Wang , Lawrence H. Staib , James S. Duncan

Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Li Pan , Jundong Liu , Mingqin Shi , Chi Wah Wong , Kei Hang Katie Chan

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Early diagnosis and intervention for Autism Spectrum Disorder (ASD) has been shown to significantly improve the quality of life of autistic individuals. However, diagnostics methods for ASD rely on assessments based on clinical presentation…

Image and Video Processing · Electrical Eng. & Systems 2025-03-05 Suryansh Vidya , Kush Gupta , Amir Aly , Andy Wills , Emmanuel Ifeachor , Rohit Shankar

Functional magnetic resonance imaging (fMRI) data is characterized by its complexity and high--dimensionality, encompassing signals from various regions of interests (ROIs) that exhibit intricate correlations. Analyzing fMRI data directly…

Applications · Statistics 2024-01-18 Yeseul Jeon , Jeong-Jae Kim , SuMin Yu , Junggu Choi , Sanghoon Han

Current models on Explainable Artificial Intelligence (XAI) have shown an evident and quantified lack of reliability for measuring feature-relevance when statistically entangled features are proposed for training deep classifiers. There has…

Signal Processing · Electrical Eng. & Systems 2023-02-27 Juan Manuel Mayor-Torres , Sara Medina-DeVilliers , Tessa Clarkson , Matthew D. Lerner , Giuseppe Riccardi

Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by atypical brain maturation. However, the adaptation of transfer learning paradigms in machine learning for ASD research remains notably limited. In this study,…

Machine Learning · Computer Science 2025-09-16 Kush Gupta , Amir Aly , Emmanuel Ifeachor , Rohit Shankar

The objective of this study is to derive functional networks for the autism spectrum disorder (ASD) population using the group ICA and dictionary learning model together and to classify ASD and typically developing (TD) participants using…

Neurons and Cognition · Quantitative Biology 2021-06-17 Xin Yang , Ning Zhang , Donglin Wang

Currently, the diagnosis of Autism Spectrum Disorder (ASD) is dependent upon a subjective, time-consuming evaluation of behavioral tests by an expert clinician. Non-invasive functional MRI (fMRI) characterizes brain connectivity and may be…

Machine Learning · Computer Science 2020-05-26 Cooper J. Mellema , Alex Treacher , Kevin P. Nguyen , Albert Montillo

Anatomical brain parcellations dominate rs-fMRI-based Autism Spectrum Disorder (ASD) classification, yet their rigid boundaries may fail to capture the idiosyncratic connectivity patterns that characterise ASD. We present a graph-based deep…

Computer Vision and Pattern Recognition · Computer Science 2026-03-04 Syeda Hareem Madani , Noureen Bibi , Adam Rafiq Jeraj , Sumra Khan , Anas Zafar , Rizwan Qureshi

Resting-state functional MRI (rs-fMRI) scans hold the potential to serve as a diagnostic or prognostic tool for a wide variety of conditions, such as autism, Alzheimer's disease, and stroke. While a growing number of studies have…

Computer Vision and Pattern Recognition · Computer Science 2018-06-14 Meenakshi Khosla , Keith Jamison , Amy Kuceyeski , Mert Sabuncu

Autism spectrum disorder (ASD) is regarded as a brain disease with globally disrupted neuronal networks. Even though fMRI studies have revealed abnormal functional connectivity in ASD, they have not reached a consensus of the disrupted…

Computer Vision and Pattern Recognition · Computer Science 2017-07-26 Hongyoon Choi

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Neurons and Cognition · Quantitative Biology 2017-12-22 Ravi Tejwani , Adam Liska , Hongyuan You , Jenna Reinen , Payel Das

Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by atypical brain connectivity. One of the crucial steps in addressing ASD is its early detection. This study introduces a novel computational framework that…

Applications · Statistics 2026-03-31 Abigail Kelly , Ramchandra Rimal , Arpan Sainju

We propose a novel optimization framework to predict clinical severity from resting state fMRI (rs-fMRI) data. Our model consists of two coupled terms. The first term decomposes the correlation matrices into a sparse set of representative…

Neurons and Cognition · Quantitative Biology 2024-11-25 Niharika Shimona D'Souza , Mary Beth Nebel , Nicholas Wymbs , Stewart H. Mostofsky , Archana Venkataraman

Autism Spectrum Disorder (ASD) is a pervasive developmental disorder of the central nervous system, primarily manifesting in childhood. It is characterized by atypical and repetitive behaviors. Currently, diagnostic methods mainly rely on…

Neurons and Cognition · Quantitative Biology 2025-03-21 Yiqian Luo , Qiurong Chen , Fali Li , Liang Yi , Peng Xu , Yangsong Zhang

We propose a model for diagnosing Autism spectrum disorder (ASD) using multimodal magnetic resonance imaging (MRI) data. Our approach integrates brain connectivity data from diffusion tensor imaging (DTI) and functional MRI (fMRI),…

Neurons and Cognition · Quantitative Biology 2024-10-10 Lu Wei , Yi Huang , Guosheng Yin , Fode Zhang , Manxue Zhang , Bin Liu

Autism spectrum disorder(ASD) is a lifelong neurodevelopmental condition that affects social communication and behavior. Investigating functional magnetic resonance imaging (fMRI)-based brain functional connectome can aid in the…

Neurons and Cognition · Quantitative Biology 2023-07-21 Anushree Bannadabhavi , Soojin Lee , Wenlong Deng , Xiaoxiao Li

Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by atypical functional brain connectivity and subtle structural alterations. rs-fMRI has been widely used to identify disruptions in large-scale brain…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Ansar Rahman , Hassan Shojaee-Mend , Sepideh Hatamikia
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