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Related papers: BioBridge: Bridging Biomedical Foundation Models v…

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Humans understand the world through the integration of multiple sensory modalities, enabling them to perceive, reason about, and imagine dynamic physical processes. Inspired by this capability, multimodal foundation models (MFMs) have…

Artificial Intelligence · Computer Science 2025-10-07 Xuehai He

Foundation models (FMs) have demonstrated strong performance across diverse pathology tasks. While there are similarities in the pre-training objectives of FMs, there is still limited understanding of their complementarity, redundancy in…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Brennan Flannery , Thomas DeSilvio , Jane Nguyen , Satish E. Viswanath

Biometrics is the science and technology of measuring and analyzing biological data of human body, extracting a feature set from the acquired data, and comparing this set against to the template set in the database. Experimental studies…

Artificial Intelligence · Computer Science 2010-11-30 K. Sasidhar , Vijaya L Kakulapati , Kolikipogu Ramakrishna , K. KailasaRao

Existing data-centric methods for protein science generally cannot sufficiently capture and leverage biology knowledge, which may be crucial for many protein tasks. To facilitate research in this field, we create ProteinKG65, a knowledge…

Quantitative Methods · Quantitative Biology 2022-11-15 Siyuan Cheng , Xiaozhuan Liang , Zhen Bi , Huajun Chen , Ningyu Zhang

Multimodal physiological signals, such as EEG, ECG, EOG, and EMG, are crucial for healthcare and brain-computer interfaces. While existing methods rely on specialized architectures and dataset-specific fusion strategies, they struggle to…

Signal Processing · Electrical Eng. & Systems 2026-03-18 Wei-Bang Jiang , Xi Fu , Yi Ding , Cuntai Guan

Biological multimodal large language models (MLLMs) have emerged as powerful foundation models for scientific discovery. However, existing models are specialized to a single modality, limiting their ability to solve inherently cross-modal…

Machine Learning · Computer Science 2026-03-17 Wonbin Lee , Dongki Kim , Sung Ju Hwang

The injection of domain-specific knowledge is crucial for adapting language models (LMs) to specialized fields such as biomedicine. While most current approaches rely on unstructured text corpora, this study explores two complementary…

Computation and Language · Computer Science 2026-04-21 Jaafer Klila , Sondes Bannour Souihi , Rahma Boujelben , Nasredine Semmar , Lamia Hadrich Belguith

Knowledge graphs (KGs), with their structured representation capabilities, offer promising avenue for enhancing Retrieval Augmented Generation (RAG) systems, leading to the development of KG-RAG systems. Nevertheless, existing methods often…

Information Retrieval · Computer Science 2025-10-17 Yikuan Hu , Jifeng Zhu , Lanrui Tang , Chen Huang

Standardising the representation of biomedical knowledge among all researchers is an insurmountable task, hindering the effectiveness of many computational methods. To facilitate harmonisation and interoperability despite this fundamental…

Knowledge Graph (KG) completion is an important task that greatly benefits knowledge discovery in many fields (e.g. biomedical research). In recent years, learning KG embeddings to perform this task has received considerable attention.…

Machine Learning · Computer Science 2022-08-01 Adil Bahaj , Safae Lhazmir , Mounir Ghogho

Existing biomedical benchmarks do not provide end-to-end infrastructure for training, evaluation, and inference of models that integrate multimodal biological data and a broad range of machine learning tasks in therapeutics. We present…

Machine Learning · Computer Science 2026-01-23 Alejandro Velez-Arce , Jesus Caraballo , Marinka Zitnik

Recent advances in neural interfacing have enabled significant improvements in human-computer interaction, rehabilitation, and neuromuscular diagnostics. Motor unit (MU) decomposition from surface electromyography (sEMG) is a key technique…

Neurons and Cognition · Quantitative Biology 2025-10-22 D. Halatsis , P. Mamidanna , J. Pereira , D. Farina

Knowledge-based biomedical data science (KBDS) involves the design and implementation of computer systems that act as if they knew about biomedicine. Such systems depend on formally represented knowledge in computer systems, often in the…

Artificial Intelligence · Computer Science 2022-09-13 Tiffany J. Callahan , Harrison Pielke-Lombardo , Ignacio J. Tripodi , Lawrence E. Hunter

Foundation models (FMs) currently dominate news headlines. They employ advanced deep learning architectures to extract structural information autonomously from vast datasets through self-supervision. The resulting rich representations of…

The electrocardiogram (ECG) is a cost-effective, highly accessible and widely employed diagnostic tool. With the advent of Foundation Models (FMs), the field of AI-assisted ECG interpretation has begun to evolve, as they enable model reuse…

Artificial Intelligence · Computer Science 2026-01-30 Francesca Filice , Edoardo De Rose , Simone Bartucci , Francesco Calimeri , Simona Perri

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Graph embedding learning that aims to automatically learn low-dimensional node representations, has drawn increasing attention in recent years. To date, most recent graph embedding methods are evaluated on social and information networks…

Biological foundation models (BioFMs), pretrained on large-scale biological sequences, have recently shown strong potential in providing meaningful representations for diverse downstream bioinformatics tasks. However, such models often rely…

Machine Learning · Computer Science 2026-02-10 Yifan Wu , Jiyue Jiang , Xichen Ye , Yiqi Wang , Chang Zhou , Yitao Xu , Jiayang Chen , He Hu , Weizhong Zhang , Cheng Jin , Jiao Yuan , Yu Li

Continual learning in computer vision faces the critical challenge of catastrophic forgetting, where models struggle to retain prior knowledge while adapting to new tasks. Although recent studies have attempted to leverage the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Xusheng Cao , Haori Lu , Linlan Huang , Fei Yang , Xialei Liu , Ming-Ming Cheng

Functional connectivity (FC) derived from resting-state fMRI plays a critical role in personalized predictions such as age and cognitive performance. However, applying foundation models(FM) to fMRI data remains challenging due to its high…

Neurons and Cognition · Quantitative Biology 2025-08-26 Yanwen Wang , Xinglin Zhao , Yijin Song , Xiaobo Liu , Yanrong Hao , Rui Cao , Xin Wen