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Recent advances in natural language processing (NLP) owe their success to pre-training language models on large amounts of unstructured data. Still, there is an increasing effort to combine the unstructured nature of LMs with structured…

Computation and Language · Computer Science 2023-12-22 Juraj Vladika , Alexander Fichtl , Florian Matthes

We propose a novel deep neural network architecture to integrate imaging and genetics data, as guided by diagnosis, that provides interpretable biomarkers. Our model consists of an encoder, a decoder and a classifier. The encoder learns a…

Biomedical knowledge graphs (KGs) encode rich, structured information critical for drug discovery tasks, but extracting meaningful insights from large-scale KGs remains challenging due to their complex structure. Existing biomedical…

Modeling biological sequences such as DNA, RNA, and proteins is crucial for understanding complex processes like gene regulation and protein synthesis. However, most current models either focus on a single type or treat multiple types of…

Genomics · Quantitative Biology 2024-10-16 Weixi Xiang , Xueting Han , Xiujuan Chai , Jing Bai

Foundation models (FMs) have shown great promise in medical imaging, but most FMs are trained on unimodal data within isolated domains, such as brain MRI alone. Human aging and disease arise through coordinated biological processes across…

Computer Vision and Pattern Recognition · Computer Science 2026-05-11 Qiangqiang Wu , Grace McIlvain , Zhou Yu , Junhao Wen

Accurately predicting molecular properties is a challenging but essential task in drug discovery. Recently, many mono-modal deep learning methods have been successfully applied to molecular property prediction. However, the inherent…

Machine Learning · Computer Science 2024-09-16 Xiaohua Lu , Liangxu Xie , Lei Xu , Rongzhi Mao , Shan Chang , Xiaojun Xu

Foundation models have achieved remarkable success across many domains, relying on pretraining over vast amounts of data. Graph-structured data often lacks the same scale as unstructured data, making the development of graph foundation…

Graph-structured data underpins many critical applications. While foundation models have transformed language and vision via large-scale pretraining and lightweight adaptation, extending this paradigm to general, real-world graphs is…

Machine Learning · Computer Science 2026-05-22 Maya Bechler-Speicher , Yoel Gottlieb , Andrey Isakov , David Abensur , Ami Tavory , Daniel Haimovich , Ido Guy , Udi Weinsberg

Recent biosignal foundation models (FMs) have demonstrated promising performance across diverse clinical prediction tasks, yet systematic evaluation on long-duration multimodal data remains limited. We introduce SignalMC-MED, a benchmark…

Machine Learning · Computer Science 2026-03-11 Fredrik K. Gustafsson , Xiao Gu , Mattia Carletti , Patitapaban Palo , David W. Eyre , David A. Clifton

Knowledge-intensive tasks pose a significant challenge for Machine Learning (ML) techniques. Commonly adopted methods, such as Large Language Models (LLMs), often exhibit limitations when applied to such tasks. Nevertheless, there have been…

Machine Learning · Computer Science 2024-05-20 Albert Sawczyn , Jakub Binkowski , Piotr Bielak , Tomasz Kajdanowicz

Multi-omics data offer unprecedented insights into complex biological systems, yet their high dimensionality, sparsity, and intricate interactions pose significant analytical challenges. Network-based approaches have advanced multi-omics…

Existing ML benchmarks lack the depth and diversity of annotations needed for evaluating models on business process management (BPM) tasks. BPM is the practice of documenting, measuring, improving, and automating enterprise workflows.…

Cardiac biosignals, such as electrocardiograms (ECG) and photoplethysmograms (PPG), are of paramount importance for the diagnosis, prevention, and management of cardiovascular diseases, and have been extensively used in a variety of…

Biomedical networks (or graphs) are universal descriptors for systems of interacting elements, from molecular interactions and disease co-morbidity to healthcare systems and scientific knowledge. Advances in artificial intelligence,…

Machine Learning · Computer Science 2025-02-07 Michelle M. Li , Kexin Huang , Marinka Zitnik

Knowledge graphs (KGs) are powerful tools that codify relational behaviour between entities in knowledge bases. KGs can simultaneously model many different types of subject-predicate-object and higher-order relations. As such, they offer a…

Social and Information Networks · Computer Science 2020-10-27 Charilaos I. Kanatsoulis , Nicholas D. Sidiropoulos

Brain decoding, a pivotal field in neuroscience, aims to reconstruct stimuli from acquired brain signals, primarily utilizing functional magnetic resonance imaging (fMRI). Currently, brain decoding is confined to a per-subject-per-model…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Shizun Wang , Songhua Liu , Zhenxiong Tan , Xinchao Wang

Existing knowledge graph (KG) embedding models have primarily focused on static KGs. However, real-world KGs do not remain static, but rather evolve and grow in tandem with the development of KG applications. Consequently, new facts and…

Computation and Language · Computer Science 2023-04-11 Yuanning Cui , Yuxin Wang , Zequn Sun , Wenqiang Liu , Yiqiao Jiang , Kexin Han , Wei Hu

Foundation models (FMs) are driving a prominent shift in biomedical imaging from task-specific models to unified backbone models for diverse tasks. This opens an avenue to integrate imaging, pathology, clinical records, and genomics data…

Quantitative Methods · Quantitative Biology 2026-04-23 Amgad Muneer , Kai Zhang , Ibraheem Hamdi , Rizwan Qureshi , Muhammad Waqas , Shereen Fouad , Hazrat Ali , Syed Muhammad Anwar , Jia Wu

Biomedical knowledge graphs are increasingly large, dynamic, and multimodal, driven by rapid advances in biotechnology such as high-throughput sequencing. Machine learning models can infer previously unobserved biomedical relationships and…

Machine Learning · Computer Science 2026-05-12 Yousef A. Radwan , Yao Li , Qing Qing , Ziqi Xu , Qixin Zhang , Yongcheng Jing , Renqiang Luo , Xikun Zhang

Cross-domain recommendation (CDR) can help customers find more satisfying items in different domains. Existing CDR models mainly use common users or mapping functions as bridges between domains but have very limited exploration in fully…

Information Retrieval · Computer Science 2022-06-28 Li Zhang , Yan Ge , Jun Ma , Jianmo Ni , Haiping Lu
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