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Objectives: This study examines human Photoplethysmogram (PPG) along with Electrocardiogram (ECG) signals to study cardiac autonomic imbalance in epileptic seizures. The significance and the prevalence of changes in PPG morphological…

Signal Processing · Electrical Eng. & Systems 2019-12-12 Seyede Mahya Safavi , Ninaz Valisharifabad , Robert Sabino , Hsinchung Chen , Ali HeydariGorji , Demi Tran , Jack Lin , Beth Lopour , Pai H. Chou

Identifying preictal states -- periods during which seizures are more likely to occur -- remains a central challenge in clinical computational neuroscience. In this study, we introduce a novel framework that embeds functional brain…

Neurons and Cognition · Quantitative Biology 2025-05-21 Steven Rico-Aparicio , Martin Guillemaud , Alice Longhena , Vincent Navarro , Louis Cousyn , Mario Chavez

Activity in the human brain moves between diverse functional states to meet the demands of our dynamic environment, but fundamental principles guiding these transitions remain poorly understood. Here, we capitalize on recent advances in…

Epilepsy is a well-known neuronal disorder that can be identified by interpretation of the electroencephalogram (EEG) signal. Usually, the length of an EEG signal is quite long which is challenging to interpret manually. In this work, we…

Machine Learning · Computer Science 2019-03-07 Md Mursalin , Syed Shamsul Islam , Md Kislu Noman , Adel Ali Al-Jumaily

Functional brain networks can change rapidly as a function of stimuli or cognitive shifts. Tracking dynamic functional connectivity is particularly challenging as it requires estimating the structure of the network at each moment as well as…

Methodology · Statistics 2024-04-30 Wan-Chi Hsin , Uri T. Eden , Emily P. Stephen

Patients with idiopathic generalised epilepsy (IGE) typically have normal conventional magnetic resonance imaging (MRI), hence MRI based diagnosis is challenging. Anatomical abnormalities underlying brain dysfunctions in IGE are unclear and…

Neurons and Cognition · Quantitative Biology 2020-09-30 Nishant Sinha , Yujiang Wang , Justin Dauwels , Marcus Kaiser , Thomas Thesen , Rob Forsyth , Peter Neal Taylor

Chimera states---the coexistence of synchrony and asynchrony in a nonlocally-coupled network of identical oscillators---are often used as a model framework for epileptic seizures. Here, we explore the dynamics of chimera states in a network…

Neurons and Cognition · Quantitative Biology 2020-12-02 Henry M. Mitchell , Peter Sheridan Dodds , J. Matthew Mahoney , Christopher M. Danforth

To define the neural networks responsible of the epileptic seizure, we had to study the electrophysiological signal in a proper way. The early recognition of the seizure build up could also be defined through the time space mapping of the…

Signal Processing · Electrical Eng. & Systems 2019-11-19 Ridha Jarray , Nawel Jmail , Abir Hadriche , Tarek Frikha , Chokri Ben Amar

Epilepsy is a prevalent neurological disorder affecting 50 million individuals worldwide and 1.2 million Americans. There exist millions of pediatric patients with intractable epilepsy, a condition in which seizures fail to come under…

Machine Learning · Computer Science 2023-09-07 Bliss Singhal , Fnu Pooja

In the study of randomly connected neural network dynamics there is a phase transition from a `simple' state with few equilibria to a `complex' state characterised by the number of equilibria growing exponentially with the neuron…

Disordered Systems and Neural Networks · Physics 2020-06-24 J. R. Ipsen , A. D. H. Peterson

Epileptic seizure prediction from electroencephalographic (EEG) recordings remains challenging due to strong inter-patient variability and the complex temporal structure of neural signals. This paper presents a patient-adaptive transformer…

Machine Learning · Computer Science 2026-03-31 Mohamed Mahdi , Asma Baghdadi

We consider the electrical signals recorded from a subdural array of electrodes placed on the pial surface of the brain for chronic evaluation of epileptic patients before surgical resection. A simple and computationally fast method to…

Medical Physics · Physics 2007-11-18 Eshel Ben-Jacob , Stefano Boccaletti , Anna Pomyalov , Itamar Procaccia , Vernon L. Towle

Epilepsy surgery, particularly for temporal lobe epilepsy (TLE), remains a vital treatment option for patients with drug-resistant seizures. However, accurately predicting surgical outcomes remains a significant challenge. This study…

Neurons and Cognition · Quantitative Biology 2025-07-22 Martin Guillemaud , Alice Longhena , Louis Cousyn , Valerio Frazzini , Bertrand Mathon , Vincent Navarro , Mario Chavez

Predicting future system behaviour from past observed behaviour (time series) is fundamental to science and engineering. In computational neuroscience, the prediction of future epileptic seizures from brain activity measurements, using EEG…

The cerebral cortex spontaneously displays different patterns of activity that evolve over time according to the brain state. Sleep, wakefulness, resting states, and attention are examples of a wide spectrum of physiological states that can…

Understanding emotional processing in the human brain requires examining the complex interactions between different brain regions. While previous studies have identified specific regions involved in emotion processing, a holistic network…

Neurons and Cognition · Quantitative Biology 2024-12-13 Sepehr Gourabi , Parinaz Khosravani , Shahrzad Nosrat , Roya Mohammadi , Masoud Lotfalipour

An epileptic seizure is a transient event of abnormal excessive neuronal discharge in the brain. This unwanted event can be obstructed by detection of electrical changes in the brain that happen before the seizure takes place. The automatic…

Machine Learning · Computer Science 2016-04-29 Z. Roshan Zamir

Epileptic seizure forecasting, combined with the delivery of preventative therapies, holds the potential to greatly improve the quality of life for epilepsy patients and their caregivers. Forecasting seizures could prevent some potentially…

Signal Processing · Electrical Eng. & Systems 2020-05-18 Nhan Duy Truong , Yikai Yang , Christina Maher , Armin Nikpour , Omid Kavehei

In recent years, network analyses have been used to evaluate brain reorganization following stroke. However, many studies have often focused on single topological scales, leading to an incomplete model of how focal brain lesions affect…

Neurons and Cognition · Quantitative Biology 2014-09-10 Fabrizio De Vico Fallani , Floriana Pichiorri , Giovanni Morone , Marco Molinari , Fabio Babiloni , Febo Cincotti , Donatella Mattia

The electrical stimulation to the seizure onset zone (SOZ) serves as an efficient approach to seizure suppression. Recently, seizure dynamics have gained widespread attendance in its network propagation mechanisms. Compared with the direct…

Neurons and Cognition · Quantitative Biology 2024-06-17 Zhichao Liang , Guanyi Zhao , Yinuo Zhang , Weiting Sun , Jingzhe Lin , Jialin Wang , Quanying Liu