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We assess electrical brain dynamics before, during, and after one-hundred human epileptic seizures with different anatomical onset locations by statistical and spectral properties of functionally defined networks. We observe a concave-like…

Neurons and Cognition · Quantitative Biology 2013-11-25 Kaspar A. Schindler , Stephan Bialonski , Marie-Therese Horstmann , Christian E. Elger , Klaus Lehnertz

Drug-resistant epilepsy is traditionally characterized by pathologic cortical tissue comprised of seizure-initiating `foci'. These `foci' are thought to be embedded within an epileptic network whose functional architecture dynamically…

Neurons and Cognition · Quantitative Biology 2016-02-17 Ankit Khambhati , Brian Litt , Danielle S. Bassett

Epilepsy is known to drastically alter brain dynamics during seizures (ictal periods), but its effects on background (non-ictal) brain dynamics remain poorly understood. To investigate this, we analyzed an in-house dataset of brain activity…

Epilepsy is a disorder characterised by spontaneous, recurrent seizures. Both local and network abnormalities have been associated with epilepsy, and the exact processes generating seizures are thought to be heterogeneous and…

Neurons and Cognition · Quantitative Biology 2019-01-07 Yujiang Wang , Gabrielle Marie Schroeder , Nishant Sinha , Peter Neal Taylor

Epilepsy which is characterized by seizures is studied using EEG signals by recording the electrical activity of the brain. Different types of communication between different parts of the brain are characterized by many state of the art…

Machine Learning · Computer Science 2020-09-29 Mohammad Mansour , Fouad Khnaisser , Hmayag Partamian

Epilepsy is a neurological disorder arising from anomalies of the electrical activity in the brain, affecting about 0.5--0.8\% of the world population. Several studies investigated the relationship between seizures and brainwave…

Machine Learning · Computer Science 2018-01-25 Paolo Detti , Garazi Zabalo Manrique de Lara , Renato Bruni , Marco Pranzo , Francesco Sarnari

Epileptic seizures are one of the most well-known dysfunctions of the nervous system. During a seizure, a highly synchronized behavior of neural activity is observed that can cause symptoms ranging from mild sensual malfunctions to the…

Neurons and Cognition · Quantitative Biology 2011-08-01 Christian Kuehn , Christian Meisel

Purpose: The understanding of brain activity, and in particular events such as epileptic seizures, lies on the characterisation of the dynamics of the neural networks. The theory of non-linear dynamics provides signal analysis techniques…

Medical Physics · Physics 2007-05-23 C. Silva , I. R. Pimentel , A. Andrade , J. P. Foreid , E. Ducla-Soares

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

Neurons and Cognition · Quantitative Biology 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

In many realistic networks, the edges representing the interactions between the nodes are time-varying. There is growing evidence that the complex network that models the dynamics of the human brain has time-varying interconnections, i.e.,…

Neurons and Cognition · Quantitative Biology 2016-11-29 G Manjunath

The dynamics underlying epileptic seizures are well understood. We present a novel analysis of seizure-like events (SLEs) in an \textit{ex vivo} whole hippocampus, as well as a modeling study that sheds light on the underlying network…

Biological Physics · Physics 2007-05-23 Benjamin H. Singer , Miron Derchansky , Peter L. Carlen , Michal Zochowski

Information transmission in the human brain is a fundamentally dynamic network process. In partial epilepsy, this process is perturbed and highly synchronous seizures originate in a local network, the so-called epileptogenic zone (EZ),…

Neurons and Cognition · Quantitative Biology 2019-06-19 Simona Olmi , Spase Petkoski , Maxime Guye , Fabrice Bartolomei , Viktor Jirsa

We investigate states of enhanced activity in a biological neuronal network composed of pulse-coupled oscillators. The synaptic couplings between the neurons are dynamic, modeling spike time dependent plasticity. The network exhibits…

Disordered Systems and Neural Networks · Physics 2012-08-17 Daniel Ritterskamp , Rudolf Friedrich

Epileptic seizures are characterised by abnormal brain dynamics at multiple scales, engaging single neurons, neuronal ensembles and coarse brain regions. Key to understanding the cause of such emergent population dynamics, is capturing the…

Neurons and Cognition · Quantitative Biology 2022-12-13 Dominic RW Burrows

We investigate assortativity of functional brain networks before, during, and after one-hundred epileptic seizures with different anatomical onset locations. We construct binary functional networks from multi-channel electroencephalographic…

Data Analysis, Statistics and Probability · Physics 2013-09-24 Stephan Bialonski , Klaus Lehnertz

Epilepsy is one of the most common and yet diverse set of chronic neurological disorders. This excessive or synchronous neuronal activity is termed seizure. Electroencephalogram signal processing plays a significant role in detection and…

Signal Processing · Electrical Eng. & Systems 2021-09-29 Paul Grant , Md Zahidul Islam

Epileptic seizures are characterized by abnormal and excessive neural activity, where cortical network dynamics seem to become unstable. However, most of the time, during seizure-free periods, cortex of epilepsy patients shows perfectly…

Neurons and Cognition · Quantitative Biology 2021-04-06 Annika Hagemann , Jens Wilting , Bita Samimizad , Florian Mormann , Viola Priesemann

Epilepsy is a chronic neurological disorder affecting more than 50 million people globally. An epileptic seizure acts like a temporary shock to the neuronal system, disrupting normal electrical activity in the brain. Epilepsy is frequently…

Neurons and Cognition · Quantitative Biology 2021-01-26 Matheus B. Guerrero , Raphaël Huser , Hernando Ombao

The brain is a high-dimensional directional network system consisting of many regions as network nodes that influence each other. The directional influence from one region to another is referred to as directional connectivity. Epilepsy is a…

Applications · Statistics 2022-08-18 Yaotian Wang , Guofen Yan , Seiji Tanabe , Chang-Chia Liu , Shayan Moosa , Mark S. Quigg , Tingting Zhang

Epilepsy is one of the most prevalent neurological conditions, where an epileptic seizure is a transient occurrence due to abnormal, excessive and synchronous activity in the brain. Electroencephalogram signals emanating from the brain may…

Neurons and Cognition · Quantitative Biology 2023-12-05 Paul Grant , Md Zahidul Islam
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