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Excess mortality, i.e. the difference between expected and observed mortality, is used to quantify the death toll of mortality shocks, such as infectious disease-related epidemics and pandemics. However, predictions of expected mortality…

Applications · Statistics 2025-02-18 Ainhoa-Elena Leger , Silvia Rizzi , Ugofilippo Basellini

Joint models (JMs) for longitudinal and time-to-event data are an important class of biostatistical models in health and medical research. When the study population consists of heterogeneous subgroups, the standard JM may be inadequate and…

Methodology · Statistics 2024-10-31 Sida Chen , Danilo Alvares , Marco Palma , Jessica K. Barrett

In the past six decades, lifespan inequality has varied greatly within and among countries even while life expectancy has continued to increase. How and why does mortality change generate this diversity? We derive a precise link between…

Populations and Evolution · Quantitative Biology 2013-11-22 Duncan O. S. Gillespie , Meredith V. Trotter , Shripad D. Tuljapurkar

Heterogeneity is a hallmark of complex diseases. Regression-based heterogeneity analysis, which is directly concerned with outcome-feature relationships, has led to a deeper understanding of disease biology. Such an analysis identifies the…

Methodology · Statistics 2022-11-29 Ziye Luo , Xinyue Yao , Yifan Sun , Xinyan Fan

Recent work has focused attention on statistical inference for the population distribution of the number of sexual partners based on survey data. The characteristics of these distributions are of interest as components of mathematical…

Disordered Systems and Neural Networks · Physics 2007-05-23 Mark S. Handcock , James Holland Jones , Martina Morris

We investigate the parameter estimation of regression models with fixed group effects, when the group variable is missing while group related variables are available. This problem involves clustering to infer the missing group variable…

Methodology · Statistics 2020-12-29 Matthieu Marbac , Mohammed Sedki , Christophe Biernacki , Vincent Vandewalle

High-frequency mortality data have attracted growing attention, but their use has largely been confined to specific applications rather than general modelling and forecasting. Such data pose new challenges to traditional mortality models…

Applications · Statistics 2026-05-14 Ziting Miao , Han Li , Yuyu Chen

Various stochastic models have been proposed to estimate mortality rates. In this paper we illustrate how machine learning techniques allow us to analyze the quality of such mortality models. In addition, we present how these techniques can…

Applications · Statistics 2017-05-10 Philippe Deprez , Pavel V. Shevchenko , Mario V. Wüthrich

Extreme value statistics provides accurate estimates for the small occurrence probabilities of rare events. While theory and statistical tools for univariate extremes are well-developed, methods for high-dimensional and complex data sets…

Methodology · Statistics 2021-01-06 Sebastian Engelke , Jevgenijs Ivanovs

Different ways of calculating mortality ratios during epidemics have yielded very different results, particularly during the current COVID-19 pandemic. We formulate both a survival probability model and an associated infection…

Populations and Evolution · Quantitative Biology 2020-10-06 Lucas Böttcher , Mingtao Xia , Tom Chou

Death events commonly arise from complex interactions among interrelated causes, formally classified in reporting practices as underlying and contributing. Leveraging information from death certificates, these interactions can be naturally…

Applications · Statistics 2025-10-03 Giovanni Romanò , Cristian Castiglione , Daniele Durante

An essential input of annuity pricing is the future retiree mortality. From observed age-specific mortality data, modeling and forecasting can be taken place in two routes. On the one hand, we can first truncate the available data to…

Applications · Statistics 2020-09-21 Han Lin Shang , Steven Haberman

The analysis of multivariate functional curves has the potential to yield important scientific discoveries in domains such as healthcare, medicine, economics and social sciences. However, it is common for real-world settings to present…

Methodology · Statistics 2024-07-23 Tui Nolan , Sylvia Richardson , Hélène Ruffieux

In demographic literature, forecast uncertainty is often quantified with a statistical model. This model-based approach may potentially suffer from drawbacks, namely model misspecification, selection effect, and lack of finite-sample…

Applications · Statistics 2026-05-29 Han Lin Shang

Survival models are used in various fields, such as the development of cancer treatment protocols. Although many statistical and machine learning models have been proposed to achieve accurate survival predictions, little attention has been…

Machine Learning · Computer Science 2020-03-26 Hrushikesh Loya , Pranav Poduval , Deepak Anand , Neeraj Kumar , Amit Sethi

Civil registration vital statistics (CRVS) data are used to produce national estimates of maternal mortality, but are often subject to substantial reporting errors due to misclassification of maternal deaths. The accuracy of CRVS systems…

Applications · Statistics 2019-09-19 Emily Peterson , Doris Chou , Ann-Beth Moller , Alison Gemmill , Lale Say , Leontine Alkema

We present some analytic results for the steady states of the Penna model of sen escence, generalised to allow genetically identical individuals to die at differ ent ages via an arbitrary survival function. Modelling this with a Fermi…

Soft Condensed Matter · Physics 2009-11-07 J. B. Coe , Y. Mao , M. E. Cates

In several countries, including Italy, a prominent approach to population health surveillance involves conducting repeated cross-sectional surveys at short intervals of time. These surveys gather information on the health status of…

Applications · Statistics 2025-04-10 Mattia Stival , Lorenzo Schiavon , Stefano Campostrini

Distribution regression has recently attracted much interest as a generic solution to the problem of supervised learning where labels are available at the group level, rather than at the individual level. Current approaches, however, do not…

Machine Learning · Statistics 2021-01-18 Ho Chung Leon Law , Danica J. Sutherland , Dino Sejdinovic , Seth Flaxman

Understanding how and why certain communities bear a disproportionate burden of disease is challenging due to the scarcity of data on these communities. Surveys provide a useful avenue for accessing hard-to-reach populations, as many…

Methodology · Statistics 2023-07-27 Stephanie M. Wu , Briana Joy K. Stephenson