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Compartmental epidemic models with dynamics that evolve over a graph network have gained considerable importance in recent years but analysis of these models is in general difficult due to their complexity. In this paper, we develop two…

Populations and Evolution · Quantitative Biology 2023-05-31 Sei Zhen Khong , Lanlan Su

Worldwide, many millions of people die suddenly and unexpectedly each year, either with or without a prior history of cardiovascular disease. Such events are sparse (once in a lifetime), many victims will not have had prior investigations…

Machine Learning · Computer Science 2023-09-06 Yola Jones , Fani Deligianni , Jeff Dalton , Pierpaolo Pellicori , John G F Cleland

We consider the challenges that arise when fitting complex ecological models to 'large' data sets. In particular, we focus on random effect models which are commonly used to describe individual heterogeneity, often present in ecological…

Methodology · Statistics 2022-05-17 Ruth King , Blanca Sarzo , Víctor Elvira

Model-based Bayesian inference for sample and population-level causal estimands has been growing in popularity. This literature routinely emphasizes clear specification of the target estimand, however blind implementation of standard…

Methodology · Statistics 2026-05-12 Arman Oganisian

The opioid crisis remains a critical public health challenge in the United States. Despite national efforts which reduced opioid prescribing rates by nearly 45\% between 2011 and 2021, opioid-related overdose deaths more than tripled during…

Computers and Society · Computer Science 2025-08-20 Andrew Deas , Adam Spannaus , Dakotah D. Maguire , Jodie Trafton , Anuj J. Kapadia , Vasileios Maroulas

Many people living in low- and middle-income countries are not covered by civil registration and vital statistics systems. Consequently, a wide variety of other types of data, including many household sample surveys, are used to estimate…

Breakthroughs in cancer biology have defined new research programs emphasizing the development of therapies that target specific pathways in tumor cells. Innovations in clinical trial design have followed with master protocols defined by…

Methodology · Statistics 2020-07-09 Alexander M. Kaizer , Joseph S. Koopmeiners , Nan Chen , Brian P. Hobbs

Auxiliary information is frequently utilized in survey sampling to improve the efficiency of estimators of the finite population mean. However, the simultaneous use of multiple auxiliary variables often induces multicollinearity, which…

Methodology · Statistics 2026-04-30 Rajesh Singh , Shobh Nath Tiwari

Reducing the global burden of stillbirths is important to improving child and maternal health. Of interest is understanding patterns in the timing of stillbirths -- that is, whether they occur in the intra- or antepartum period -- because…

Applications · Statistics 2022-12-14 Michael Y. C. Chong , Monica Alexander

A canonical desideratum for prediction problems is that performance guarantees should hold not just on average over the population, but also for meaningful subpopulations within the overall population. But what constitutes a meaningful…

Machine Learning · Computer Science 2024-12-10 Jessica Dai , Nika Haghtalab , Eric Zhao

Cluster-randomized trials (CRTs) on fragile populations frequently encounter complex attrition problems where the reasons for missing outcomes can be heterogeneous, with participants who are known alive, known to have died, or with unknown…

Methodology · Statistics 2025-05-06 Guangyu Tong , Chenxi Li , Eric Velazquez , Michael O. Harhay , Fan Li

We congratulate the authors for a stimulating and valuable manuscript, providing a careful review of the state-of the-art in cross-sectional and time-series benchmarking procedures for small area estimation. They develop a novel two-stage…

Other Statistics · Statistics 2014-05-27 Rebecca C. Steorts , M. Delores Ugarte

In areas of application, including actuarial science and demography, it is increasingly common to consider a time series of curves; an example of this is age-specific mortality rates observed over a period of years. Given that age can be…

Applications · Statistics 2020-09-29 Han Lin Shang

Multilevel or hierarchical data structures can occur in many areas of research, including economics, psychology, sociology, agriculture, medicine, and public health. Over the last 25 years, there has been increasing interest in developing…

Methodology · Statistics 2018-01-08 Bernet S. Kato , Carel F. W. Peeters

In this work we present a spatial approach to model and investigate mortality data referenced over a Lexis structure. We decompose the force of mortality into two interpretable components: a Markov random field, smooth with respect to time,…

Applications · Statistics 2018-10-23 Fabio Divino , Denekew Bitew Belay , Nico Keilman , Arnoldo Frigessi

Census data provide detailed information about population characteristics at a coarse resolution. Nevertheless, fine-grained, high-resolution mappings of population counts are increasingly needed to characterize population dynamics and to…

Machine Learning · Computer Science 2019-07-02 Guillaume Derval , Frédéric Docquier , Pierre Schaus

Complex systems are fascinating because their rich macroscopic properties emerge from the interaction of many simple parts. Understanding the building principles of these emergent phenomena in nature requires assessing natural complex…

Neurons and Cognition · Quantitative Biology 2022-11-17 Anna Levina , Viola Priesemann , Johannes Zierenberg

Many population genetic models have been developed for the purpose of inferring population size and growth rates from random samples of genetic data. We examine two popular approaches to this problem, the coalescent and the…

Populations and Evolution · Quantitative Biology 2014-08-29 Erik M. Volz , Simon DW Frost

Survival regression is widely used to model time-to-events data, to explore how covariates may influence the occurrence of events. Modern datasets often encompass a vast number of covariates across many subjects, with only a subset of the…

Methodology · Statistics 2024-09-18 Abhishek Mandal , Abhisek Chakraborty

The Lee Carter modelling framework is widely used because of its simplicity and robustness despite its inability to model specific cohort effects. A large number of extensions have been proposed that model cohort effects but there is no…

Populations and Evolution · Quantitative Biology 2010-03-10 Edouard Debonneuil
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