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High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly with respect to the study of living cells and organisms.…

We present a multimodal approach for measuring the three-dimensional (3D) refractive index (RI) and fluorescence distributions of live cells by combining optical diffraction tomography (ODT) and 3D structured illumination microscopy (SIM).…

Optics · Physics 2018-01-04 Seungwoo Shin , Doyeon Kim , Kyoohyun Kim , Yongkeun Park

The integration of miniaturized optical spectrometers into mobile platforms will have an unprecedented impact on applications ranging from unmanned aerial vehicles (UAVs) to mobile phones. To address this demand, silicon photonics stands…

Applied Physics · Physics 2018-05-09 Mario C. M. M. Souza , Andrew Grieco , Newton C. Frateschi , Yeshaiahu Fainman

Many optical microscopy techniques rely on structured illumination by way of a projected image (eg. structured illumination microscopy) or a tailored angular distribution of light (eg. ptychography). Electro-optical equipment such as…

Physics Education · Physics 2020-09-23 Antony Orth

Spatial Heterodyne Spectroscopy (SHS) is a relatively novel interferometric technique similar to the Fourier transform spectroscopy with heritage from the Michelson Interferometer. An imaging detector is used at the output of a SHS to…

Point-scanning microscopy approaches are transforming super-resolution imaging. Despite achieving parallel high-speed imaging using multifocal techniques, efficient multi-color capability with high-quality illumination is currently lacking.…

Optics · Physics 2023-03-14 Ning Xu , Sarah E. Bohndiek , Zexing Li , Cilong Zhang , Qiaofeng Tan

Fluorescence microscopy and derived techniques are continuously looking for photodetectors able to guarantee increased sensitivity, high spatial and temporal resolution and ease of integration into modern microscopy architectures. Recent…

Free-space optical communication (FSO) can achieve fast, secure and license-free communication without need for physical cables, making it a cost-effective, energy-efficient and flexible solution when the fiber connection is unavailable. To…

Signal Processing · Electrical Eng. & Systems 2023-04-18 Yao Zhang , Hua-Ying Liu , Xiaoyi Liu , Peng Xu , Xiang Dong , Pengfei Fan , Xiaohui Tian , Hua Yu , Dong Pan , Zhijun Yin , Guilu Long , Shi-Ning Zhu , Zhenda Xie

We present the design of a productionized end-to-end stereo depth sensing system that does pre-processing, online stereo rectification, and stereo depth estimation with a fallback to monocular depth estimation when rectification is…

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

High accuracy 3D surface information is required for many construction robotics tasks such as automated cement polishing or robotic plaster spraying. However, consumer-grade depth cameras currently found in the market are not accurate…

Robotics · Computer Science 2022-09-05 Teng Foong Lam , Hermann Blum , Roland Siegwart , Abel Gawel

Taking photographs in low light using a mobile phone is challenging and rarely produces pleasing results. Aside from the physical limits imposed by read noise and photon shot noise, these cameras are typically handheld, have small apertures…

Computer Vision and Pattern Recognition · Computer Science 2019-10-28 Orly Liba , Kiran Murthy , Yun-Ta Tsai , Tim Brooks , Tianfan Xue , Nikhil Karnad , Qiurui He , Jonathan T. Barron , Dillon Sharlet , Ryan Geiss , Samuel W. Hasinoff , Yael Pritch , Marc Levoy

Blood oxygen saturation (SpO$_2$) is an important indicator for pulmonary and respiratory functionalities. Clinical findings on COVID-19 show that many patients had dangerously low blood oxygen levels not long before conditions worsened. It…

Signal Processing · Electrical Eng. & Systems 2025-02-04 Xin Tian , Chau-Wai Wong , Sushant M. Ranadive , Min Wu

Astronomical telescopes suffer from a tradeoff between field of view (FoV) and image resolution: increasing the FoV leads to an optical field that is under-sampled by the science camera. This work presents a novel computational imaging…

Instrumentation and Methods for Astrophysics · Physics 2025-08-07 Robin Swanson , Esther Y. H. Lin , Masen Lamb , Suresh Sivanandam , Kiriakos N. Kutulakos

Among super-resolution microscopy techniques, structured illumination microscopy (SIM) shows great advances of low phototoxicity, high speed, and excellent performance in long-term dynamic observation, making it especially suitable for live…

Optics · Physics 2025-02-07 Han Wang , Wenshu Wang , Xinzhu Xu , Meiqi Li , Peng Xi

This paper introduces an innovative approach to silicon and glass via inspection, which combines hybrid field microscopy with photometric stereo. Conventional optical microscopy techniques are generally limited to superficial inspections…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Gugeong Sung

Non-line-of-sight (NLOS) imaging enables monitoring around corners and is promising for diverse applications. The resolution of transient NLOS imaging is limited to a centimeter scale, mainly by the temporal resolution of the detectors.…

Optical spectrometers are widely used scientific equipment with many applications involving material characterization, chemical analysis, disease diagnostics, surveillance, etc. Emerging applications in biomedical and communication fields…

Vascular segmentation extracts blood vessels from images and serves as the basis for diagnosing various diseases, like ophthalmic diseases. Ophthalmologists often require high-resolution segmentation results for analysis, which leads to…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Yan Hu , Zhongxi Qiu , Dan Zeng , Li Jiang , Chen Lin , Jiang Liu
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