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Pairwise models are used widely to model epidemic spread on networks. These include the modelling of susceptible-infected-removed (SIR) epidemics on regular networks and extensions to SIS dynamics and contact tracing on more exotic networks…

Populations and Evolution · Quantitative Biology 2018-09-24 István Z. Kiss , Joel C. Miller , Péter L. Simon

In this article, we consider a dynamic epidemiology model for the spread of the COVID-19 infection. Starting from the classical SEIR model, the model is modified so as to better describe characteristic features of the underlying pathogen…

Populations and Evolution · Quantitative Biology 2020-05-22 Daniela Calvetti , Alexander Hoover , Johnie Rose , Erkki Somersalo

Infectious disease epidemiologists routinely fit stochastic epidemic models to time series data to elucidate infectious disease dynamics, evaluate interventions, and forecast epidemic trajectories. To improve computational tractability,…

The surprisingly mercurial Covid-19 pandemic has highlighted the need to not only accelerate research on infectious disease, but to also study them using novel techniques and perspectives. A major contributor to the difficulty of containing…

Populations and Evolution · Quantitative Biology 2022-07-21 Aminur Rahman , Angela Peace , Ramesh Kesawan , Souparno Ghosh

Epidemic models are invaluable tools to understand and implement strategies to control the spread of infectious diseases, as well as to inform public health policies and resource allocation. However, current modeling approaches have…

Methodology · Statistics 2026-05-12 Caitlin Ward , Rob Deardon , Alexandra M. Schmidt

An individualized risk prediction model that dynamically updates the probability of a clinical event from a specific cause is valuable for physicians to be able to optimize personalized treatment strategies in real-time by incorporating all…

Methodology · Statistics 2019-04-22 Qing Liu , Gong Tang , Joseph P. Costantino , Chung-Chou H. Chang

During the early stage of the COVID-19 pandemic, many countries implemented non-pharmaceutical interventions (NPIs) to control the transmission of SARS-CoV-2, the causative pathogen of COVID-19. Among those NPIs, quarantine measures were…

Populations and Evolution · Quantitative Biology 2022-03-04 Renquan Zhang , Yu Wang , Zheng Lv , Sen Pei

In this paper, we propose a continuous-time stochastic intensity model, namely, two-phase dynamic contagion process(2P-DCP), for modelling the epidemic contagion of COVID-19 and investigating the lockdown effect based on the dynamic…

Physics and Society · Physics 2020-06-30 Zezhun Chen , Angelos Dassios , Valerie Kuan , Jia Wei Lim , Yan Qu , Budhi Surya , Hongbiao Zhao

Recent advances in interrupted time series analysis permit characterization of a typical non-linear interruption effect through use of generalized additive models. Concurrently, advances in latent time series modeling allow efficient…

Applications · Statistics 2025-11-11 RJ Waken , Fengxian Wang , Sarah A. Eisenstein , Tim McBride , Kim Johnson , Karen Joynt-Maddox

In 2005, Chen et al introduced a sequential importance sampling (SIS) procedure to analyze zero-one two-way tables with given fixed marginal sums (row and column sums) via the conditional Poisson (CP) distribution. They showed that compared…

Statistics Theory · Mathematics 2011-11-29 Jing Xi , Ruriko Yoshida , David Haws

This paper introduces a way of modeling the epidemic transmission rate using a stochastic process of the form $(\beta_t = \varphi(t)P_t : t \ge 0)$, where the positive deterministic function $\varphi(t)$ models the impact of a public health…

Probability · Mathematics 2026-04-03 Duvan Cataño , Raul Morán , Leon A. Valencia

Endpoint dilution (TCID50) assays cannot count the number of infectious virions (IVs), and instead are limited to counting the number of Specific INfections caused by the sample (SIN). The latter depends not only on whether virions are…

COVID-19 pandemic has brought to the fore epidemiological models which, though describing a wealth of behaviors, have previously received little attention in signal processing literature. In this work, a generalized time-varying…

Methodology · Statistics 2025-08-13 Barbara Pascal , Samuel Vaiter

Evaluating hospitals' performance and its relation to patients' characteristics is of utmost importance to ensure timely, effective, and optimal treatment. Such a matter is particularly relevant in areas and situations where the healthcare…

The novel Coronavirus disease (COVID-19) is a highly contagious virus and has spread all over the world, posing an extremely serious threat to all countries. Automatic lung infection segmentation from computed tomography (CT) plays an…

Image and Video Processing · Electrical Eng. & Systems 2021-07-29 Yichi Zhang , Qingcheng Liao , Lin Yuan , He Zhu , Jiezhen Xing , Jicong Zhang

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…

Methodology · Statistics 2026-01-21 Xiaoru Huang , Tonghui Yu , Xiaoyu Liu

Infectious disease modeling and forecasting have played a key role in helping assess and respond to epidemics and pandemics. Recent work has leveraged data on disease peak infection and peak hospital incidence to fit compartmental models…

The evolution of the COVID-19 epidemic has been accompanied by accumulating evidence on the underlying epidemiological parameters. Hence there is potential for models providing mid-term forecasts of the epidemic trajectory using such…

Applications · Statistics 2020-11-10 Peter Congdon

The rapidly spreading Covid-19 that affected almost all countries, was first reported at the end of 2019. As a consequence of its highly infectious nature, countries all over the world have imposed extremely strict measures to control its…

Populations and Evolution · Quantitative Biology 2020-07-13 Semra Ahmetolan , Ayse Humeyra Bilge , Ali Demirci , Ayse Peker-Dobie , Onder Ergonul

In matched observational studies with continuous treatments, individuals with different treatment doses but the same or similar covariate values are paired for causal inference. While inexact covariate matching (i.e., covariate imbalance…

Methodology · Statistics 2025-02-13 Anthony Frazier , Siyu Heng , Wen Zhou
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