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Explainability is highly-desired in Machine Learning (ML) systems supporting high-stakes policy decisions in areas such as health, criminal justice, education, and employment. While the field of explainable ML has expanded in recent years,…

Machine Learning · Computer Science 2023-02-21 Kasun Amarasinghe , Kit Rodolfa , Hemank Lamba , Rayid Ghani

Deep learning methods have been very effective for a variety of medical diagnostic tasks and has even beaten human experts on some of those. However, the black-box nature of the algorithms has restricted clinical use. Recent explainability…

Computer Vision and Pattern Recognition · Computer Science 2020-05-29 Amitojdeep Singh , Sourya Sengupta , Vasudevan Lakshminarayanan

Explainability in AI and ML models is critical for fostering trust, ensuring accountability, and enabling informed decision making in high stakes domains. Yet this objective is often unmet in practice. This paper proposes a general purpose…

Statistical Finance · Quantitative Finance 2025-09-03 N. Jean , G. Le Pera

The trade-off between accuracy and interpretability has long been a challenge in machine learning (ML). This tension is particularly significant for emerging interpretable-by-design methods, which aim to redesign ML algorithms for…

Machine Learning · Computer Science 2025-05-28 Geyu Liang , Senne Michielssen , Salar Fattahi

Artificial Intelligence models are becoming increasingly more powerful and accurate, supporting or even replacing humans' decision making. But with increased power and accuracy also comes higher complexity, making it hard for users to…

Artificial Intelligence · Computer Science 2019-07-10 Vivian S. Silva , André Freitas , Siegfried Handschuh

We present a systematic study of medical-domain interpretability in Large Language Models (LLMs). We study how the LLMs both represent and process medical knowledge through four different interpretability techniques: (1) UMAP projections of…

Machine Learning · Computer Science 2026-02-24 Razvan Marinescu , Victoria-Elisabeth Gruber , Diego Fajardo

Transparency, user trust, and human comprehension are popular ethical motivations for interpretable machine learning. In support of these goals, researchers evaluate model explanation performance using humans and real world applications.…

Artificial Intelligence · Computer Science 2019-10-31 Bernease Herman

We provide a novel notion of what it means to be interpretable, looking past the usual association with human understanding. Our key insight is that interpretability is not an absolute concept and so we define it relative to a target model,…

Artificial Intelligence · Computer Science 2018-10-30 Amit Dhurandhar , Vijay Iyengar , Ronny Luss , Karthikeyan Shanmugam

The integration of Artificial Intelligence in the development of computer systems presents a new challenge: make intelligent systems explainable to humans. This is especially vital in the field of health and well-being, where transparency…

Explainability is an essential reason limiting the application of neural networks in many vital fields. Although neuro-symbolic AI hopes to enhance the overall explainability by leveraging the transparency of symbolic learning, the results…

Artificial Intelligence · Computer Science 2024-11-08 Xin Zhang , Victor S. Sheng

This paper presents a systematic review of benchmarks and approaches for explainability in Machine Reading Comprehension (MRC). We present how the representation and inference challenges evolved and the steps which were taken to tackle…

Computation and Language · Computer Science 2020-10-02 Mokanarangan Thayaparan , Marco Valentino , André Freitas

Interpretability and explainability have gained more and more attention in the field of machine learning as they are crucial when it comes to high-stakes decisions and troubleshooting. Since both provide information about predictors and…

Machine Learning · Computer Science 2024-04-26 Benjamin Leblanc , Pascal Germain

When quantitative models are used to support decision-making on complex and important topics, understanding a model's ``reasoning'' can increase trust in its predictions, expose hidden biases, or reduce vulnerability to adversarial attacks.…

Machine Learning · Computer Science 2019-07-09 Dimitris Bertsimas , Arthur Delarue , Patrick Jaillet , Sebastien Martin

The increasing availability of large collections of electronic health record (EHR) data and unprecedented technical advances in deep learning (DL) have sparked a surge of research interest in developing DL based clinical decision support…

Machine Learning · Computer Science 2021-12-07 Di Jin , Elena Sergeeva , Wei-Hung Weng , Geeticka Chauhan , Peter Szolovits

The impressive capabilities of deep learning models are often counterbalanced by their inherent opacity, commonly termed the "black box" problem, which impedes their widespread acceptance in high-trust domains. In response, the intersecting…

Machine Learning · Computer Science 2025-09-16 Mitali Raj

In this study, we present a novel clinical decision support system and discuss its interpretability-related properties. It combines a decision set of rules with a machine learning scheme to offer global and local interpretability. More…

Methodology · Statistics 2021-07-16 Francisco Valente , Simão Paredes , Jorge Henriques

Mechanistic interpretability (MI) aims to understand AI models by reverse-engineering the exact algorithms neural networks learn. Most works in MI so far have studied behaviors and capabilities that are trivial and token-aligned. However,…

Machine Learning · Computer Science 2024-07-15 Satvik Golechha , James Dao

As the use of deep learning techniques has grown across various fields over the past decade, complaints about the opaqueness of the black-box models have increased, resulting in an increased focus on transparency in deep learning models.…

Computation and Language · Computer Science 2024-03-19 Siwen Luo , Hamish Ivison , Caren Han , Josiah Poon

Deep learning has become popular because of its potential to achieve high accuracy in prediction tasks. However, accuracy is not always the only goal of statistical modelling, especially for models developed as part of scientific research.…

Machine Learning · Computer Science 2021-10-19 Thomas P Quinn , Sunil Gupta , Svetha Venkatesh , Vuong Le

We argue that existing definitions of interpretability are not actionable in that they fail to inform users about general, sound, and robust interpretable model design. This makes current interpretability research fundamentally ill-posed.…

Machine Learning · Computer Science 2025-08-04 Pietro Barbiero , Mateo Espinosa Zarlenga , Alberto Termine , Mateja Jamnik , Giuseppe Marra