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Heterogeneous, interconnected, systems-level, molecular data have become increasingly available and key in precision medicine. We need to utilize them to better stratify patients into risk groups, discover new biomarkers and targets,…

Other Quantitative Biology · Quantitative Biology 2024-05-17 Natasa Przulj , Noel Malod-Dognin

Integrating multi-omics datasets through data-driven analysis offers a comprehensive understanding of the complex biological processes underlying various diseases, particularly cancer. Graph Neural Networks (GNNs) have recently demonstrated…

Machine Learning · Computer Science 2025-08-11 Jielong Lu , Zhihao Wu , Jiajun Yu , Jiajun Bu , Haishuai Wang

Oral cancer presents a formidable challenge in oncology, necessitating early diagnosis and accurate prognosis to enhance patient survival rates. Recent advancements in machine learning and data mining have revolutionized traditional…

Machine Learning · Computer Science 2025-06-13 Mohammad Subhi Al-Batah , Muhyeeddin Alqaraleh , Mowafaq Salem Alzboon

Modern large-scale scientific discovery requires multidisciplinary collaboration across diverse computing facilities, including High Performance Computing (HPC) machines and the Edge-to-Cloud continuum. Integrated data analysis plays a…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-08-21 Renan Souza , Tyler J. Skluzacek , Sean R. Wilkinson , Maxim Ziatdinov , Rafael Ferreira da Silva

In cancer research, clustering techniques are widely used for exploratory analyses and dimensionality reduction, playing a critical role in the identification of novel cancer subtypes, often with direct implications for patient management.…

Medical imaging provides critical evidence for clinical diagnosis, treatment planning, and surgical decisions, yet most existing imaging models are narrowly focused and require multiple specialized networks, limiting their generalization.…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Guoxin Wang , Jun Zhao , Xinyi Liu , Yanbo Liu , Xuyang Cao , Chao Li , Zhuoyun Liu , Qintian Sun , Fangru Zhou , Haoqiang Xing , Zhenhong Yang

While high-capacity AI models have advanced state-of-the-art performance, their practical deployment is often hindered by high inference costs, environmental impact, and a "one-size-fits-all" approach that ignores varying sample complexity.…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Turkoglu Mikael , Bary Tim , Thielens Vincent , Dausort Manon , Macq Benoît

Breast cancer screening, primarily conducted through mammography, is often supplemented with ultrasound for women with dense breast tissue. However, existing deep learning models analyze each modality independently, missing opportunities to…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Yiqiu Shen , Jungkyu Park , Frank Yeung , Eliana Goldberg , Laura Heacock , Farah Shamout , Krzysztof J. Geras

Prediction tasks in digital pathology are challenging due to the massive size of whole-slide images (WSIs) and the weak nature of training signals. Advances in computing, data availability, and self-supervised learning (SSL) have paved the…

Image and Video Processing · Electrical Eng. & Systems 2026-02-02 Vishwesh Ramanathan , Tony Xu , Pushpak Pati , Faruk Ahmed , Maged Goubran , Anne L. Martel

Recently, Computer-Aided Diagnosis (CAD) systems have emerged as indispensable tools in clinical diagnostic workflows, significantly alleviating the burden on radiologists. Nevertheless, despite their integration into clinical settings, CAD…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Muwei Jian , Hongyu Chen , Zaiyong Zhang , Nan Yang , Haorang Zhang , Lifu Ma , Wenjing Xu , Huixiang Zhi

The demand of transparency of clinical research results, the need of accelerating the process of transferring innovation in the daily medical practice as well as assuring patient safety and product efficacy make it necessary to extend the…

Software Engineering · Computer Science 2013-01-10 Daniela Luzi , Fabrizio Pecoraro

Multimodal learning, integrating histology images and genomics, promises to enhance precision oncology with comprehensive views at microscopic and molecular levels. However, existing methods may not sufficiently model the shared or…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Huahui Yi , Xiaofei Wang , Kang Li , Chao Li

Combining images from multi-modalities is beneficial to explore various information in computer vision, especially in the medical domain. As an essential part of clinical diagnosis, multi-modal brain tumor segmentation aims to delineate the…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 Zhongzhen Huang , Linda Wei , Shaoting Zhang , Xiaofan Zhang

Breast cancer remains the most commonly diagnosed malignancy among women in the developed world. Early detection through mammography screening plays a pivotal role in reducing mortality rates. While computer-aided diagnosis (CAD) systems…

Computer Vision and Pattern Recognition · Computer Science 2025-10-30 Shunjie-Fabian Zheng , Hyeonjun Lee , Thijs Kooi , Ali Diba

Motivation: Tumor classification using Imaging Mass Spectrometry (IMS) data has a high potential for future applications in pathology. Due to the complexity and size of the data, automated feature extraction and classification steps are…

Machine Learning · Statistics 2018-06-28 Jens Behrmann , Christian Etmann , Tobias Boskamp , Rita Casadonte , Jörg Kriegsmann , Peter Maass

The current cancer treatment practice collects multimodal data, such as radiology images, histopathology slides, genomics and clinical data. The importance of these data sources taken individually has fostered the recent raise of radiomics…

Machine Learning · Computer Science 2023-06-16 Matteo Tortora , Ermanno Cordelli , Rosa Sicilia , Lorenzo Nibid , Edy Ippolito , Giuseppe Perrone , Sara Ramella , Paolo Soda

The synergistic interpretation of anatomical information from computed tomography (CT) and metabolic information from positron emission tomography (PET) is important to oncologic imaging. However, existing deep learning methods for PET/CT…

Image and Video Processing · Electrical Eng. & Systems 2026-05-22 Xiaofeng Liu , Qianru Zhang , Thibault Marin , Menghua Xia , Chi Liu , Georges El Fakhri , Jinsong Ouyang

Multimodal learning has been demonstrated to enhance performance across various clinical tasks, owing to the diverse perspectives offered by different modalities of data. However, existing multimodal segmentation methods rely on…

Image and Video Processing · Electrical Eng. & Systems 2026-02-04 Shiyun Chen , Li Lin , Pujin Cheng , ZhiCheng Jin , JianJian Chen , HaiDong Zhu , Kenneth K. Y. Wong , Xiaoying Tang

Motivation: Multi-omics integration can improve cancer subtyping, but modality informativeness and noise vary across cancer types and patients. Existing graph-based methods optimize modality weights jointly with the classification objective…

Machine Learning · Computer Science 2026-04-28 Boyang Fan , Hengchuang Yin , Siyu Yi , Yifan Wang , Zhicheng Li , Leijiyu Zhou , Jiancheng Lv , Wei Ju

There has been much research activity in recent times about providing the data infrastructures needed for the provision of personalised healthcare. In particular the requirement of integrating multiple, potentially distributed,…

Databases · Computer Science 2008-12-16 Andrew Branson , Tamas Hauer , Richard McClatchey , Dmitry Rogulin , Jetendr Shamdasani
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